html> NanoBioTechnology

BioE 505: NanoBioTechnology

University of Illinois at Chicago
Department of BioEngineering
Spring Semester 2010

Class Schedule: Tuesdays & Thursdays, 11:00 am - 12:15 pm,

Class Meeting Rm: Room 200 SEO Building

Call No. 26858 LCD (4 Credit Hours)
Prerequisite(s): Consent of the instructors.
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COURSE CONTENTS:

MAJOR TOPICS: (HRS).

  • Fabrication of Nanoscale Structures for Applications in BioEngineering (3.0)

  • Fundamentals of Nanofabrication (3.0)

  • Nanoscale Markers: Synthesis and Uses (4.0)

  • Fundamental Properties Underlying the Design and Uses of Nanostructures in BioEngineering(12.0)
    - Thermodynamics and statistical mechanics of small bio systems
    - Transport phenomena (momentum, heat & mass transfer) in nanobio systems
    - Monte Carlo simulation methods for nanobio systems
    - Molecular dynamics simulation methods for nanobio systems
    - Computer based simulations and optimizations for nanobio systems
    - Phase transitions in nanobio systems

  • Nanoscale Sensors for Applications in BioEngineering: Current Successes and New Concepts (3.0)

  • Fundamental Properties of Biomolecules that are Foundational to Understanding Integrated Nanostructure-Biostructure Complexes and to Drug Delivery (8.0)
    - Nanobio systems intermolecular forces and potentials.
    - Molecular Positional- and self-assembly of biomolecules.
    - Dynamic combinatorial chemistry / Dynamic combinatorial library for drug design.
    - Biomolecular building blocks, protein-nanoparticle attachment.
    - Drug delivery - drug targeting - gene therapy.
    - Nanotechnology-based disease diagnostic methods and therapeutic agents

  • Integrating Manmade Nanostrcutures with Biological Structures including Biomolecules (4.0)
    - Monitoring Biomolecular Processes
    - Altering and Controlling Biomolecular Processes

  • Presentations/Examinations (8.0)

  • TOTAL NUMBER OF HOURS: (45.0)
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    RECOMMENDED BOOKS:

    1. PRINCIPLES OF NANOTECHNOLOGY - Molecular-Based Study of Condensed Matter in Small Systems, by G Ali Mansoori, (World Scientific Pub. Co, 2005).

    2. BIOLOGICAL NANOSTRUCTURES AND APPLICATIONS OF NANOSTRUCTURES IN BIOLOGY: Electrical, Mechanical & Optical Properties, by Michael A. Stroscio and Mitra Dutta, editors, (Kluwer Academic Publishers, 2004)

    3. Molecular Building Blocks for Nanotechnology, by G.A. Mansoori et al., editors, (Springer, New York), Topics in Applied Physics 109, 2007)