| Caption: |
The Actin-Myosin Contraction Cycle: The cycle of attachment and powerstroke are shown in this three-dimensional molecular animation based on X-ray crystallographic imagery. Muscle myosin is shown in blue (head piece) and the myosin lever arm changes from yellow to red during the power stroke. The binding site on the actin filament is colored green. The animation begins with the attachment of the myosin head to actin and proceeds with the release of pre-hydrolyzed Pi, the power stroke, the release of ADP, the binding of new ATP, and the cocking of the head with concomitant hydrolysis of the ATP. The actin filament clearly is moved laterally as a result of the cycle. See text Fig 7.34. Run time: 0:30 |