ANSWERS TO PHARMACOKINETICS

PRACTICE PROBLEMS

1) 10/1; 1/10

2) 0.22 L/kg

3) V_d = 15 L; K_E = 0.17 hr ^-1; T_1/2 = 4 hr; Cl = 2.6 L/hr

4) 9.99 days (10.4 days as an estimate)

5) 15.5 mg/L; 15.1 hr (15.8 hr as an estimate)

6) 4 hr; 2.33 hr

7) 180 min

8) 25 mg/L; 120 mg

9) 25.9 hr (27 hr as an estimate)

10) 72 mg; 100 mg every 6 hours