Fluoride
Calculations(2)
Fluoride Content
of Toothpastes:
-
-0.221% NaF(45% F) = 0.1%F = 1000 ppm = 1 mg/gm of toothpaste.
- -0.41%
SnF2(24% F) = 0.1%F = 1000 ppm =1 mg/gm of toothpaste.
-
Sn = 120, F=l9 X 2 = 38, total MW =158-- 38/158= 0.25X 0.4 = 0.1%F
-
-0.76% MFP (14% F) = 0.1%F = 1000 ppm =1mg/gm of toothpaste.
Fluoride Content
of Gels and Liquids:
-
-1.23% F (APF) = 12,300 ppm =12.3 gm/L =12.3mg F/ml.
-
Large fluoride tray may hold 5 ml or 61 mg F total.
-
-0.05% NaF = 0.023%F = 230 ppm = 230 mg/L= 0.23 mg/ ml.
-
Na= 23mw, F= 19 mw total=42 , 19/42= 0.45 X 0.05=0.023
Lethal Dosage:
-Adult = 1.25
gms F or 2.5 gms of NaF is lethal. (8-16 mg/kg of body weight). Best to consider
8 mg of F/kg body weight as lethal adult dose.
e.g. 80Kg
adult x 8mg/Kg =640 mg of F.
-For a child
5 mg of F/kg body weight considered toxic.
-
e.g. 20 Kg child X 5 mg/Kg body weight= 100 mg of F toxic.
-
Small F tray may hold 2 ml each. APF = 12.3 mg F/ml,
-
2 trays = 4 ml x 12.3 mg= about 50 mg. This is half the toxic dose.