Hypothalamus and Pituitary

Hypothalamus and Pituitary

Hypothalamus and Pituitary

Posterior Pituitary: neurohypophysis

Anterior pituitary: adenohypophysis

Hypothalamus and pituitary gland

Hypothalamus and pituitary gland

Regulation
of Hypothalamus

Anatomical and functional organization

Hypothalamic releasing factors for anterior pituitary hormones

Hypothalamic releasing hormones

Characteristics of  hypothalamic releasing hormones

Anterior pituitary

Anterior pituitary cells and hormones

Hypothalamus and anterior pituitary

Anterior pituitary hormones

Feedback regulation of hypothalmus/pituitary

Hypothalamus-pituitary axis

Feedback control

Feedback control of thyroid function

Feedback and restoration of homeostasis

Feedback control of growth hormone

Growth hormone vs. metabolic state

Growth hormone vs. metabolic state

Growth hormone and metabolic state

ACTH: adrenocorticotropic hormone: synthesis and regulation of secrtion

ACTH synthesis

ACTH

Addison’s Disease

b-endorphin

Regulation of ACTH secretion

Regulation of ACTH

ACTH

Regulation of ACTH

ACTH

Glycoprotein hormones

Glycoprotein hormones

Gonadotrophs

LH/FSH

Pulsitile secretion of GnRH and LH

Regulation of LH/FSH

Regulation of LH/FSH

Regulation of LH/FSH

Regulation of gonadotropin secretion

Thyrotrophs

Feedback control of thyroid function

Lacotrophs

Prolactin

Posterior pituitary hormones: ADH (AVP) and Oxytocin (really hypothalamic hormones)

Hypothalamus and posterior pituitary

Structures of ADH and oxytocin

Oxytocin: stimulates myoepithelial contractions

Oxytocin: milk ejection from lactating mammary gland

Oxytocin: uterine contractions

Oxytocin secretion is stimulated  by nursing

ADH: conserve body water and regulate tonicity of body fluids

Regulation of ADH secretion

ADH increases renal tubular absorption of water

ADH and plasma osmolality

ADH and blood pressure