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Course Description:
I. Course Description
The purpose of PR 651, the first of a two course sequence, is to integrate
the pathophysiologic abnormalities of disease states with concepts of drug action and
therapy. State-of-the art pharmacotherapy will be reviewed with pertinent pathophysiology.
Emphasis will be placed on drug preparation selection, dosing regimen design, and
therapeutic drug monitoring to assess the attainment of therapeutic efficacy and avoidance
of adverse reactions. Identification and treatment of significant drug-drug or
drug-disease state interactions will also be covered.
Pharmacotherapy of selected disease states will be illustrated using patient cases.
Students will be presented with clinical situations frequently encountered in a patient
care setting. Other areas that will be discussed include therapeutic problems which
require assessment, selection of appropriate alternatives and development of therapeutic
monitoring plans.
II. Goals
- Enhance the student's knowledge of all aspects of drug therapy and his(her)
understanding of how drugs cure disease or ameliorate signs and symptoms of disease.
- Enhance the student's therapeutic problem-solving skills so that he(she) can integrate
and apply pathophysiologic and pharmacotherapeutic knowledge in the development of drug
therapy plans.
III. Textbooks
A. Required texts
- DiPiro JT, Talbert RL, Hayes PE, Yee GC, Matzke GR and Posey LM. Pharmacotherapy: A
Pathophysiologic Approach. Third edition. Appleton & Lange; Norwalk, Connecticut.
1996.
B. Supplemental texts
- Ravel R. Clinical Laboratory Medicine: Clinical Application of Laboratory Data.
6th ed. Chicago: Year Book Medical Publishers. 1995.
- Isselbacher KJ, Braunwald E, Wilson, et al. Harrison's Principles of Internal
Medicine. 14th ed. New York: McGraw-Hill Book Co., 1994.
- Other texts as listed in handouts.
IV. Course Implementation
A self-study course syllabus is the primary source material, and may be purchased from
the University of Illinois at Chicago Health Sciences Center Bookstore [Phone:(312)
413-5550]. Included in the syllabus are goals, objectives and reading lists for each
therapeutic area. The students are expected to complete the reading assignment, understand
the course materials, and prepare the answers for the case studies.
The College of Pharmacy
The University of Illinois at Chicago
UICPHARM@UIC.EDU
Last modified: July 23, 1999
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