Lecture notesBe sure to take the CITI Research Ethics training this week. The link for instructions is here.
This week we talk about ethics in research. We will address several key issues:
- What researchers must do to ensure their study is ethical
- How the risk of harm get's weighed against the value of scientific data
- How we tell simple research error from fraud
- How can we ensure that research participants give informed consent
- What are / should be the benefits of research to participants & to the larger society
- Who the researcher is responsible to ... how do we separate self-interest & political pressure from science
Your discussion group reading (and lecture) also addresses whether the "business" of research creates incentives for fraud or shortcuts.
We will talk about the Tuskegee study, a 40 year study of syphilis in rural Alabama that led to over 400 poor, largely uneducated African-American men being left untreated. Tuskegee is the basis for some of our human subjects protections, and remains the most salient example of unethical research in the United States. Wikipedia has a nice overview of the study here.
We will spend a fair amount of time discussing the Common Rule, eight principles or procedures that underlie ethnical research
I will briefly touch on the Belmont Report and its conclusions; the CITI training will introduce that in more depth. I will also introduce the American Psychological Association rules for informed consent and IRB approval: you will all be including an informed consent document in your paper!
Lecture notes are here.
Discussion sections will meet in computer labs week 5.
Places to be announced.
- Your TA will show you how to search online for articles on your paper topic, so narrow down your topic prior to this meeting. E-mail me or your TA if you have questions about appropriate paper topics.
- Bring your laptop / Tablet if you have one ... if not we will ask students to share their laptops.
Readings: This is a few more pages than most weeks, but these raise compelling question about research.
First is an NYT piece on a massive scientific fraud in Social Psychology. Diederik Stapel faked 20 years (!) of research, producing 55 journal articles and 10 dissertations with made-up data. How did he go undetected for so long?
He was obviously a gifted con artist, but the investigating committee also noted "...a general culture of careless, selective and uncritical handling of research and data [in Behavioral Science]." According to the author: "What may be most troubling about the research culture the committees describe in their report are the plentiful opportunities and incentives for fraud."
Clinical research in developing countries discusses controversy HIV research in Malawi. Women in the control group of a parenatal (mother to child) HIV transmission study were given no treatment, even though effective treatments are available. Can investigators in a developing country use procedures that would be considered unethical in the developed world?
Discussion Group Assignment(Click for a Word copy of Week 4 assignment).
We will discuss the readings in discussion group this week, as well as ethics generally. To get ready, answer the following questions using not more than one typed page.
Reading 1: How skeptical should we be about findings in Psychology? Do you think the system "worked" in the case of Diederik Stapel, or are the temptations for ethically dubious shortcuts (or actual fraud) just too great?
Reading2: Is using a placebo - control research design in treatment trials in developing countries an example of a Tuskegee-like study? Why or why not? How do you balance the ethnic and scientific issues in this research? Hint: ethics not only concern potential harm to study participants, but the extent to which valid data will answer important questions that directly affect the target population.