Selected Manuscripts & Publications
ALI B., H. BLOOM, E. VELEDAR, D. HOUSE, R. NORVEL, S.C. DUDLEY, Jr., A.M. ZAFARI. Automated External Cardioversion Defibrillation Monitoring in Cardiac Arrest: A Randomized Trial. (2008). Trials. vol. 9:36. view pdf
SHANG L.L., G. GAO, S.C. DUDLEY, Jr. The Tail of the Cardiac Sodium Channel. Channels. (2008). vol. 2: 161 - 162. view pdf
IRAVANIAN, S., S.C. DUDLEY, Jr. The Renin-Angiotensin-Aldosterone System (RAAS) and Cardiac Arrhythmias. Heart Rhythm. (2008). vol. 5:S12-S17. view pdf
DUDLEY, S.C., Jr., and D. SIMPSON. An Imperfect Syllogism: Granulocyte Colony Stimulating Factor Mobilization and Cardiac Regeneration. (2008). J. Am. Coll. Cardiol.vol 51:1438-1439. view pdf
SHANG, L.L., A.E. PFAHNL, Z. JIAO, J. ALLEN, H. LIU, S.C. DUDLEY, Jr. NF-κB-Dependent Transcriptional Downregulation of Cardiac SCN5A Sodium Channel by Angiotensin II and H2O2. (2008). Am. J. Physiol., vol. 294:C372-9. view pdf
LONDON, B., M. MICHALEC, H. MEHDI, X. ZHU, L. KERCHNER, S. SANYAL, P.C. VISWANATHAN, A.E. PFAHNL, L.L. SHANG, M. MADHUSUDANAN, S. LAGANA, R. ALEONG, R. GUTMANN, M. J. ACKERMAN, D.M. MCNAMARA, R. WEISS, S.C. DUDLEY, Jr. A Mutation in GPD1-L Disrupts Na+ Channel Trafficking and Causes Inherited Arrhythmias. (2007). Circulation, vol. 116:2260-8. view pdf
CHOUDHARY, G., M.P. ALISTE, D.P. TIELEMAN, R.J. FRENCH, S.C. DUDLEY, Jr. Docking Orientation of µ-Conotoxin GIIIA in the Sodium Channel. (2007). Channels, vol. 1:344-352. view pdf
SHANG, L.L., A.E. PFAHNL, S. SANYAL, Z. JIAO, J. ALLEN, K. BANACH, J. FAHRENBACH, D. WEISS, W.R. TAYLOR, A.M. ZAFARI, S.C. DUDLEY, Jr. Human Heart Failure is Associated with Abnormal C-Terminus Splicing Variants in the Cardiac Sodium Channel. (2007). Circ. Res., vol. 101,1146-1154. view pdf
BLOOM, H.L., I. SHUKRULLAH, J.R. CUELLAR, M.S. LLOYD, S.C. DUDLEY Jr., A.M. ZAFARI. Long-Term Survival after Successful In-Hospital Cardiac Arrest Resuscitation. (2007). Am. Heart. J vol. 153, 831-836.
SIMPSON, D., H. LIU, T.M. FAN, R. NEREM, S.C. DUDLEY, Jr. A Tissue Engineering Approach to Progenitor Cell Delivery Results in Significant Cell Engraftment and Improved Myocardial Remodeling. (2007). Stem Cells, vol. 25:2350-2357. view pdf
KASI, V.S., H.D. XIAO, L.L. SHANG, S. IRAVANIAN, J. LANGBERG, E.A. WITHAM, Z. JIAO, C.J. GALLEGO, K.E. BERNSTEIN, S.C. DUDLEY Jr. Cardiac Restricted Angiotensin Converting Enzyme Overexpression Causes Conduction Defects and Connexin Dysregulation. (2007). Am. J. Physiol. vol. 293, H182-H192. view pdf
NEUMAN, R.B., H.L. BLOOM, I. SHUKRULLAH, L.A. DARROW, D. KLEINBAUM, D.P. JONES, S.C. DUDLEY, Jr. Oxidative Stress Markers are Associated with Persistent Atrial Fibrillation. (2007). Clin. Chem. vol. 53, 1652-1657. view pdf
PFAHNL, A.E., P.C. VISWANATHAN, R. WEISS, L.L. SHANG, S. SANYAL, V. SHUSTERMAN, C. KORNBLIT, B. LONDON, S.C. DUDLEY, Jr. A Sodium Channel Pore Mutation Causing Brugada Syndrome. (2007). Heart Rhythm vol. 4, 46-53. view pdf
IRAVANIAN, S. and S.C. DUDLEY, Jr. Oxidative Stress and the Pathogenesis of Atrial Fibrillation. (2006). Current Cardiology Reviews vol. 2, 247-254. view pdf
JIAO, Z., V.R. De JESUS, S. IRAVANIAN, D.P. CAMPBELL, J. XU, J.A. VITALI, K. BANACH, J. FAHRENBACH, S.C. DUDLEY, Jr. A Possible Mechanism of Halocarbon-Induced Cardiac Sensitization Arrhythmias. (2006). J. Mol. Cell. Cardiol. vol. 41, 698-705. view pdf
BOULDEN, B.M., J.C. ALLEN, D.A. SMITH, R.N. Al-BALDAWI, H. JO, S.C. DUDLEY, Jr. H2O2-Induced Endothelial Dysfunction Requires the NAD(P)H Oxidase. (2006). Free Radic. Biol. Med vol. 41, 810-817. view pdf
DUDLEY, Jr., S.C. Beware of Cells Bearing Gifts: Cell Replacement Therapy and Arrhythmic Risk. (2005). Circ. Res. vol. 97, 99-101. view pdf
DUDLEY, Jr., S.C., N.E. HOCH, L.A. McCANN, C.HONEYCUTT, L.DIAMANDOPOULOS, T. FUKAI, D.G. HARRISON, S.I. DIKALOV, J. LANGBERG. Atrial Fibrillation Increases Production of Superoxide by the Left Atrium and Left Atrial Appendage: Role of the NADPH and Xanthine Oxidases. (2005). Circulation vol. 112, 1266-1273. view pdf
SHANG, L. and S.C. DUDLEY, Jr. Tandem Promoters and Developmentally Regulated 5' and 3' mRNA Untranslated Regions of the Mouse scn5a Cardiac Sodium Channel. (2005). J. Biol. Chem vol. 280, 933-940. view pdf
XIAO, H.D., S. FUCHS, D.J. CAMPBELL, W. LEWIS, S.C. DUDLEY, Jr., V.S. KASI, B.D. HOIT, G. KESHELAVA, H. ZHAO, M.R. CAMPECCHI, K.E. BERNSTEIN. Mice with Cardiac Restricted Angiotensin Converting Enzyme (ACE) have Atrial Enlargement, Cardiac Arrhythmia and Sudden Death. (2004). Am. J. Pathol. vol. 165, 1019-1032. view pdf
ZAFARI, A.M., S.K. ZARTER, V. HEGGEN, P. WILSON, R.A. TAYLOR, K. REDDY, A.G. BACKSCHEIDER, S.C. DUDLEY, Jr. A Program Encouraging Early Defibrillation Results in Improved In-Hospital Resuscitation Efficacy. (2004). J. Am. Coll. Cardiol. vol. 44, 846-852. view pdf
YOTSU-YAMASHITA, M., Y.H. KIM, S.C. DUDLEY, Jr., G. CHOUDHARY, A. PFANHL, Y. OSHIMA, J.W. DALY. The Structure of Zetekitoxin AB, a Saxitoxin Analog from the Panamanian Golden Frog Atelopus zeteki: A Potent Sodium-Channel Blocker. (2004). Proc.Nat'l.Acad.Sci USA vol. 101, 4346-4351. view pdf
ZHANG, Y.M., L. SHANG, C. HARTZELL, M. NARLOW, L. CRIBBS, S.C. DUDLEY, Jr. Characterization and Regulation of T-type Ca2+ Channels in Embryonic Stem Cell-Derived Cardiomyocytes. (2003). Am. J. Physiol. vol. 285, H2770-2779. view pdf
CHOUDHARY, G., M. YOTSU-YAMASHITA, L. SHANG, T. YASUMOTO, S.C. DUDLEY, Jr. Interactions of the C-11 Hydroxyl of Tetrodotoxin with the Sodium Channel Outer Vestibule. (2003). Biophys. J. vol. 84, 287-294. view pdf
CAI, H.,Z. LI, M.E. DAVIS, W. KANNER, D.G. HARRISON,S.C. DUDLEY, Jr. Akt-Dependent Phosphorylation of Serine 1179 and MEK/ERK1/2 Cooperatively Mediate Activation of the Endothelial Nitric Oxide Synthase by Hydrogen Peroxide. (2003). Mol. Pharmacol. vol. 63, 325-333. view pdf
CHOUDHARY, G., L. SHANG, X. LI,S.C. DUDLEY, Jr. Energetic Localization of Saxitoxin in its Channel Binding Site. (2002). Biophys. J vol. 83, 912-919. view pdf
ZHANG, Y.M., C. HARTZELL, M. NARLOW, S.C. DUDLEY, Jr. Stem Cell Derived Cardiomyocytes Demonstrate Arrhythmic Potential. (2002). Circulation vol. 106, 1294-1299. view pdf
CAI, H.,Z.M. LI, A. GOETTE, F. MERA, C. HONEYCUTT, K. FERERIK, J.N. WILCOX, S.C. DUDLEY, Jr., D.G. HARRISON,J.J. LANGBERG. Downregulation of Nitric Oxide Synthase Expression and Nitric Oxide Production in Atrial Fibrillation: Potential Mechanisms of Atrial Thrombosis and Stroke. (2002). Circulation vol. 106, 2854-2858. view pdf
CAI, H., Z. LI, S. DIKALOV, S.C. DUDLEY, Jr., D.G. HARRISON. NAD(P)H Oxidase Derived Hydrogen Peroxide Mediates Endothelial Nitric Oxide Production Stimulated by Angiotensin II. (2002). J. Biol. Chem. vol. 277, 48311-48317. view pdf
PENZOTTI, J.L.,G. LIPKIND, H.A. FOZZARD,S.C. DUDLEY, Jr. Specific Neosaxitoxin Interactions with the Na+ Channel Outer Vestibule Determined by Mutant Cycle Analysis. (2001). Biochemistry vol. 80, 698-706. view pdf
CHOUDHARY, G., S.C. DUDLEY. Heart Failure, Oxidative Stress and Ion Channel Modulation. (2001). Congestive Heart Failure vol. May/June 2002, 148-155. view pdf
DUDLEY, Jr., S.C., N. CHANG, J. HALL, G. LIPKIND, H.A. FOZZARD, & R.J. FRENCH. µ-Conotoxin GIIIA Interactions with the Voltage-Gated Na+ Channel Predict a Clockwise Arrangement of the Domains. (2000). J. Gen. Physiol. vol. 116, 679-689. view pdf
