Yong Zhao, MD, Ph.D.

Assistant Professor

Phone: 312-996-8950
Fax: 1-312-413-0437
E-mail: yongzhao@uic.edu

Office and Laboratory Location:
University of Illinois at Chicago, Department of Medicine
Section of Endocrinology, Diabetes and Metabolism
Mailing Address: 1819 West Polk St., M/C 640
Express Delivery (Fed Ex-UPS): 835 S. Wolcott, 6th Floor, Room E625

Chicago, IL 60612

MD - Shandong Weifang Medical Science, China
MS - Shandong Academy of Medical Science, China
PhD - Shanghai Second Military Medical University, China

Research Objectives:

Yong Zhao and Theodore Mazzone. Human cord blood stem cells and the journey to a cure for type 1 diabetes. (2010) Autoimmunity Reviews. 10 (2): 103-107.

Zhao Y, Guo C, Hwang D, Lin B, Dingeldein M, Mihailescu D, Sam S, Sidhwani S, Zhang Y, Jain S, Skidgel RA, Prabhakar BS, Mazzone T, Holterman MJ. (2010). Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model. Biochem Biophys Res Commun. 399 (4): 629-36.

Yong Zhao, Brian Lin, Michael Dingeldein, Chengshan Guo, David Hwang, Mark J. Holterman. (2010) The new type of human blood stem cell: a double-edged sword for the treatment of type 1 diabetes. Translational Research 155: 211-16.

Yong Zhao, Brian Lin, Robert Darflinger, Yongkang Zhang, Mark Holterman, Randal A. Skidgel. (2009) Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice. Plos ONE. 4 (1): e4226.

Yong Zhao. (2007) New hope for diabetics: adult blood stem cells can make insulin. Discovery Medicine.7:63-67. Invited review article.

Zhao Y, Huang Z, Lazzarini P, Wang Y, Di A, Chen M. (2007) A unique human blood-derived cell population displays high potential for producing insulin. Biochem Biophys Res Commun. 360: 205-211.

Zhao Y, Huang Z, Qi M, Lazzarini P, Mazzone T. (2007) Immune regulation of T lymphocyte by a newly characterized human umbilical cord blood stem cell. Immunology Letters 108:78-87.

Zhao Y and Mazzone T. (2006) Turning "waste" into gold: Identification of novel stem cells from human umbilical cord blood. Discovery Medicine 6:87-89. Invited review article.

Zhao Y, Wang H and Mazzone T. (2006) Identification of pluripotent stem cells from umbilical cord blood with embryonic and hematopoietic characteristics. Experimental Cell Research 312: 2454-2464.

Zhao Y, Mazzone T. (2005) Human umbilical cord blood-derived f-macrophages retin pluripotentiality after thromobopoietin expansion. Experimental Cell Research310: 311-318.

Zhao Y, Glesne D, Huberman E. (2003) A human peripheral blood monocyte-derived subset acts as pluripotent stem cells as pluripotent stem cells. Proc. Natl. Acad. Sci. USA 100:2426.

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