Understanding the past. Empowering your future.
You, your family, and hereditary cancer.
@2013 Familial Gastrointestinal Cancer Unit, University of Illinois at Chicago
840 S. Wood Street (MC 716), Chicago. IL 60612 · Phone (312) 413-
Last Update: 10/22/2013
Genetics and Cancer
There are some genes which help protect humans from developing cancer. Examples of these genes are: APC, MLH1, MSH2, MSH6, STK11, or BRCA. These genes, and others like them, are located on the autosomes. This means that an inherited predisposition for cancer can come from either your mother or your father, because you have one gene from each.
Some people are born with an alteration (mutation) in one of these genes. A mutation
is essentially a mis-
If an individual has an inherited mutated copy of a gene, there is a 50% risk of passing the altered gene on to his or her children. The other 50% of the time, the working copy of the gene will be passed on to his or her children. Each child has a 50% risk of receiving the mutated gene.
For more information about specific hereditary cancer syndromes please click here.
We provide comprehensive state-
|Xavier Llor, MD, PhD|
|Areas of Specialization|
|Join The Team|
|Referring a Patient|
|Genetics and Cancer|
|Is This For Me?|
|What is Genetic Counseling?|
|Becoming a Patient|
|Location & Directions|
|Genetic Basis of Cancer|
|Genes and DNA|