Research Interests
Laboratory: Model systems: Caulobacter crescentus and Agrobacterium tumefaciens, model organisms for studying the bacterial cell cycle. Studies of the role of DNA methylation in bacteria, specifically its effects on cellular physiology and its potential as a novel antimicrobial drug target, and of the maintenance of complex bacterial genomes. We are expanding this research into Vibrio cholerae.
Clinical: Flat and early neoplasms of the gastrointestinal tract. Enhancement of routine upper and lower endoscopy screening techniques using chromoendoscopy. |
Education
& Training |
College: Harvard University (1982-1986)
Medical School: University of California, San Francisco (1987-1992)
Internship & Residency:
Internal Medicine, University of California, San Francisco (1992-1995)
Gastroenterology Clinical & Research Fellowships:
Stanford University (1995-2002) |
Select Publications
1. Reisenauer A, Kahng LS, McCollum S, and Shapiro, L. Bacterial DNA methylation: a cell cycle regulator? Journal of Bacteriology, 1999. 181(17): 5135-5139. 2. Kahng LS and Shapiro L. The CcrM DNA methyltransferase of Agrobacterium tumefaciens is essential, and its activity is cell cycle regulated. Journal of Bacteriology, 2001. 183(10):3065-3075. 3. Soetikno RM, Kahng LS, Ono A, and Fujii T. Flat and Depressed Colorectal Neoplasms. Current Opinion in Gastroenterology, 2003. 19(1):69-75. 4. Kahng LS and Shapiro L. Polar localization of replicon origins in the multipartite genomes of Agrobacterium tumefaciens and Sinorhizobium meliloti Journal of Bacteriology, 2003. 185(11):3384-91. 5. Friedland S, Kahng LS, Torosis J, and Soetikno RM. Ligate and let go. Gastrointestinal Endoscopy, 2003. 58(3):473-4.
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