UIC Section of Hepatology

SCOTT J. COTLER, MD
Associate Professor of Medicine
Chief, Section of Hepatology

Education and Training
College: The University of Michigan (BS, Psychology, 1982-1986)
Medical School: The University of Chicago, Pritzker School of Medicine (MD, 1986-1990)
Internship & Residency: The University of Chicago (Internal Medicine 1990-1993)
Fellowship: RUSH-Presbyterian-St. Luke's Medical Center (Gastroenterology 1993-1995)
Fellowship: University of Washington Medical Center (Hepatology 1995-1996)

Basic Research Interests
In the Section of Hepatology, we are studying a number of aspects of Non-Alcoholic Fatty Liver Disease (NAFLD). We are working to develop noninvasive ways to measure fat in the liver that does not require a liver biopsy. We are examining the mechanisms that lead to liver damage in Non-Alcoholic Steatohepatitis (NASH). We are also studying new therapies for NASH. We hope that our research efforts will lead to a better understanding of, and better treatment for the most common cause of liver disease in the United States.

Contact Information
Section of Hepatology (MC 787)
Department of Medicine
840 South Wood Street
Chicago, IL 60612-7323
(312) 355-4267

Select Publications
• Jensen DM, Cotler SJ, Lam H, Harb G, Shillington A. A comparison of hepatitis C treatment and outcomes at academic, private, and Veterans' Affairs treatment centres. Aliment Pharmacol Ther 2004;19:69-77.
• Cotler SJ, Cotler S, Gambera M, Benedetti E, Jensen DM, Testa G. Adult living donor liver transplantation: Perspectives from 100 liver transplant surgeons. Liver Transpl 2003;9:637-644.
• Cotler SJ, Morrissey MJ, Wiley TE, Layden TJ, Jensen DM. A pilot study of the combination of cyclosporine A and interferon alfacon-1 for the treatment of hepatitis C in previous nonresponder patients. J Clin Gastroenterol, 2003;36:352-355.
• Cotler SJ, Layden JE, Neumann AU, Jensen DM. First phase hepatitis C viral kinetics in previous nonresponder patients. J Viral Hepat 2003;10:43-49.
• Tung BY, Emong MJ, Bronner MP, Raaka SD, Cotler SJ, Kowdley KV. Hepatitis C, iron status, and disease severity: relationship with HFE mutations. Gastroenterology 2003;124:318-326.
• Cotler SJ, Diaz G, Gundlapalli S, Jakate S, Chawla A, Mital D, Jensik S, Jensen DM. Characteristics of hepatitis C in renal transplant candidates. J Clin Gastroenterol 2002;35:191-195.
• Cotler SJ, Craft T, Ferris MW, Morrissey, M. McCone J, Reddy KR, Conrad A, Jensen DM, Albrecht J, Taylor MW. Induction of Il-1ra in resistant and responsive hepatitis C patients following treatment with IFN-con1. J Interferon Cytokine Res 2002;22:549-554.
• Cotler SJ, Reddy KR, McCone J, Wolfe DL, Liu A, Craft TR, Ferris MW, Conrad AJ, Albrecht J, Morrissey M, Ganger DR, Rosenblate H, Blatt LM, Jensen DM, Taylor MW. An analysis of acute changes in interleukin-6 levels after treatment of hepatitis C with consensus interferon. J Interferon Cytokine Res 2001;21:1011-1019.
• Cotler SJ, Patil R, McNutt RA, Speroff T, Banaad-Omiotek G, Ganger DR, Rosenblate H, Kaur S, Cotler S, Jensen DM. Patients' values for health states associated with hepatitis C and physicains' estimates of those values. Am J Gastroenterol 2001;96:2730-2736.
• Patil R, Cotler SJ, Banaad-Omiotek G, McNutt RA, Brown MD, Cotler S, Jensen DM. Physicians' preference values for hepatitis C health states and antiviral therapy: A survey. BMC Gastroenterol 2001;1:6.
• Cotler SJ, McNutt R, Patil R, Banaad-Omiotek G, Morrissey M, Abrams R, Cotler S, Jensen DM. Adult living donor liver transplantation: preferences about donation outside of the medical community. Liver Transpl 2001;7:335-340.
• Cotler SJ, Jakate S, Jensen DM. Resolution of cirrhosis in autoimmune hepatitis with corticosteroid therapy. J Clin Gastroenterol 2001;32:428-430.
• Cotler SJ, Ganger DR, Kaur S, Rosenblate H, Jakate S, Sullivan DG, Ng KW, Gretch DR, Jensen DM. Daily interferon therapy for hepatitis C virus infection in liver transplant recipients. Transplantation 2001;71:261-266.
• Mahajani RV, Cotler SJ, Uzer MF. Efficacy of endoscopic management of anastomotic biliary strictures after hepatic transplantion. Endoscopy 2000;32:943-949.
• Polyak SJ, Nousbaum JB, Larson AM, Cotler S, Carithers RL, Gretch DR. The PKR-interacting domain in the hepatitis C virus second envelope glycoprotein gene is highly conserved in genotype 1-infected patients treated with interferon. J Infect Dis 2000;182:397-204.
• Cotler SJ, Wartelle CF, Larson AM, Gretch DR, Jensen DM, Carithers RL. Pretreatment symptoms and dosing regimen predict side effects of interferon therapy for hepatitis C. J Viral Hepat 2000;7:211-217.
• Cotler SJ, Taylor SL, Gretch DR, Bronner MP, Rizk R, Perkins JD, Carithers RL. Hyperbilirubinemia and cholestatic liver injury in hepatitis C-infected liver transplant recipients. Am J Gastroenterol 2000;95:753-759.
• Chang M, Marquardt AP, Wood BL, Williams O, Cotler SJ, Taylor SL, Carithers RL, Gretch DR. In situ distribution of hepatitis C virus replicative-intermediate RNA in hepatitic tissue and its correlation with liver disease. J Virol 2000;74:944-955.
• Cotler SJ, Emond MJ, Gretch DR, Wilson, JJ, Lin M, Bronner, MP, Kowdley KV. Relation between iron concentration and hepatitis C virus RNA level in liver tissue. J Clin Gastroenterol 1999;29:322-326.
• Cotler SJ, Jensen DM, Kesten S. Hepatitis C virus infection and lung transplantation: A survey of practices. J Heart Lung Transplant 1999;18:456-459.
• Cotler SJ, Gaur LK, Gretch DR, Wile M, Strong DM, Bronner MP, Carithers RL, Emond MJ, Perkins JD, Nelson KA. Donor-recipient sharing of HLA class II alleles predicts earlier recurrence and accelerated progression of hepatitis C following liver transplantation. Tissue Antigens 1998;52:435-443.
• Cotler SJ, Bronner MP, Press RD, Carlson TH, Emond MJ, Perkins JD, Carithers RL, Kowdley KV. End-stage liver disease without hemochromatosis associated with elevated hepatic iron index. J Hepatol 1998;29:257-262.
• Cotler SJ, Gretch DR, Bronner MP, Tateyama H, Emond MJ, dela Rosa C, Perkins JD, Carithers RL. Hepatitis G virus co-infection does not alter the course of recurrent hepatitis C virus infection in liver transplantation recipients. Hepatology 1997;26:432-436.
• Lloyd DM, Cotler SJ, Letai AG, Stuart FP, Thistlethwaite JR Jr. Pancreas-graft immunogenicity and pretreatment with anti-class II monoclonal antibodies. Diabetes 1989;38(Suppl. 1):104-108.