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University of Illinois College of Medicine at Chicago >> Education, Departments & Programs >> Departments >> Research >> Alip Borthaur PhD

Alip Borthaur, Ph.D.

Academic Title: Research Assistant Professor of Medicine

Administrative Positions:

Division: Gastroenterology and Hepatology

Location: 840 S. Wood St., 718E CSB (MC 716), Chicago, IL 60612

Phone: (312)569-7463 (Office) Fax: (312)996-5103



Faculty Positions:

Clinical Specialties

Research Interests

Selected Publications

  1. Borthakur A and Ramadoss CS. Aerobic formation of ketodiene from linoleic acid by one of the two forms of lipoxygenase isolated from Bengal gram.  J. Agric. Food Chem. 34:1016-1018, 1986.
  2. Borthakur A, Bhat BG and Ramadoss CS. Positional specificities of oxygenation of linoleic acid by two forms of Bengal gram lipoxygenase. J. Biosci 11:257-263, 1987.
  3. Ramadoss CS, Shenoy BC and Borthakur A. Isolation and characterization of a novel haemoprotein b559 from Bengal gram. Biochem. J. 243:723-728, 1987.
  4. Borthakur A, Appu Rao AG and Ramadoss CS. Physico-chemical studies on two forms of Bengal gram lipoxygenase: Implications for structural differences. Biochim. et Biophys. Acta. 958:40-51, 1988.
  5. Borthakur A, Appu Rao AG and Ramadoss CS. Bengal gram lipoxygenase: Fluorescence quenching study of the interaction of the interaction of linoleic acid and 13- and 9- hydroperoxylinoleic acid with two forms of the enzyme. J. Agric. Food Chem. 38:1487-1490, 1990.
  6. Borthakur A, Gill RK, Hodges K, Ramaswamy K, Hecht G and Dudeja PK. Enteropathogenic E. coli inhibits butyrate uptake in Caco-2 cells by altering apical membrane MCT1 level. Am. J. Physiol. Gastrointest. Liver Physiol. 290:G-30-35, 2006.
  7. Borthakur A, Bhattacharyya S, Dudeja PK and Tobacman JK. Carrageenan induces interleukin-8 production through distinct BCL-10 pathway in normal intestinal epithelial cells.  Am. J. Physiol. Gastrointest. Liver Physiol. 292:G829-38, 2007.
  8. Borthakur A, Gill RK, Tyagi S, Koutsouris A, Alrefai WA, Hecht GA, Ramaswamy K and Dudeja PK. The probiotic Lactobacillus acidophilus stimulates Cl-/OH- exchange activity in human intestinal epithelial cells. J. Nutr. 138:1355-1359, 2008.
  9. Tobacman JK, Bhattacharyya S, Borthakur A and Dudeja PK. The carrageenan diet : Not recommended. Science. 321:1040-1041, 2008.
  10. Esmaili A, Nazir SF, Borthakur A, Yu D, Turner JR, Saksena S, Singla A, Hecht GA, Alrefai WA and Gill RK. Enteropathogenic E. coli inhibits intestinal serotonis transporter (SERT) function and expression. Gastroenterology. 137:2074-2083, 2009.
  11. Borthakur A, Anbazhagan AN, Kumar A, Raheja G, Singh V, Ramaswamy K and Dudeja PK. The Probiotic Lactobacillus plantarum counteracts TNF-a­induced down-regulation of SMCT1 expression and function. Am. J. Physiol. Gastrointest. Liver Physiol. 299:G928-934, 2010.
  12. Borthakur A, Bhattacharyya S, Anbazhagan AN, Dudeja PK and Tobacman JK. Sustained inflammation in response to carrageenan exposure in colonic epithelial cells attributed to activation of NF-.B-Bcl10 loop. Biochim. Biophys. Acta. (Molecular basis of Disease) 1822:1300-1307, 2012.
  13. Borthakur A, Priyamvada S, Kumar A, Gill RK, Alrefai WA and Dudeja PK. A novel nutrient sensing mechanism underlies substrate-induced regulation of Monocarboxylate transporter 1. Am. J. Physiol. Gastrointest. Liver Physiol. 303:G1126-1133, 2012.