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University of Illinois College of Medicine at Chicago >> Education, Departments & Programs >> Departments >> Research >> Andrei L. Gartel, PhD
Academic Title: Associate Professor of Medicine and Molecular Genetics
Division: Gastroenterology and Hepatology
Location: 840 S. Wood St., (MC 787), Chicago, IL 60612
PhD, Institute of Virology, Academy of Medical Sciences of the USSR (1983)
Postdoctoral Research Associate, University of Illinois at Chicago, Chicago, IL (1991-
Research Assistant Professor, Department of Microbiology and Immunology, University
of Illinois at Chicago, Chicago, IL (1993-
Research Assistant Professor, Department of Molecular Genetics, University of Illinois
at Chicago, Chicago, IL (1994-
Assistant Professor, Department of Medicine, University of Illinois at Chicago, Chicago,
Associate Professor, Department of Medicine, University of Illinois at Chicago, Chicago,
Internal Medicine – Hepatology research
Positive and negative regulation of oncogenic transcription factor FoxM1.
Identification of novel anticancer drugs against human neoplasia.
Regulation and expression of the cyclin-
Gartel AL, Ye X, Goufman E, Shianov P, Hay N, Najmabadi F and Tyner AL. Myc represses
the p21WAF1/CIP1 promoter and interacts with Sp1/Sp3. Proc. Natl. Acad. Sci. USA.
Gartel AL and Tyner AL. The Role for the Cdk Inhibitor p21 in Apoptosis. Mol. Cancer
Ther. 1: 639-
Kandel ES, Skeen J, Majewski N, Di Cristofano A, Pandolfi PP, Feliciano CS, Gartel
AL and Hay N. Activation of Akt/PKB abrogates G2/M cell cycle checkpoint following
DNA damage. Mol. Cell Biol. 22(22):7831-
Gartel AL and Shchors K. Mechanisms of c-
Gartel AL, Feliciano C and Tyner AL. A new method for determining the status of p53
in tumor cell lines of different origin. Oncol. Res. 13:405-
Gartel AL, Radhakrishnan SK, Serfas MS, Kwon YH and Tyner AL. A novel p21WAF1/CIP1 transcript
is highly dependent on p53 for its basal expression in mouse tissues. Oncogene. 23(49):8154-
Radhakrishnan SK and Gartel AL. The PPAR-
Radhakrishnan SK, Bhat UG, Hughes DE, Wang IC, Costa RH and Gartel AL. Identification
of a chemical inhibitor of the ongocenic transcription factor Forkhead Box M1. Cancer
Nekhai S, Bhat UG, Ammosova T, Radhakrishnan SK, Jerebtsova M, Niu X, Foster A, Kayden
TJ and Gartel AL. Novel transcriptional inhibitor ARC antagonizes HIV-
Radhakrishnan SK, Bhat UG, Halasi M, and Gartel AL. P-
Halasi M and Gartel AL. A novel mode of FoxM1 regulation: Positive auto-
Gartel AL. A new target for proteasome inhibitors: FoxM1. Expert Opin. Investig.
Bhat U, Jagadeeswaran R, Halasi M and Gartel AL. Nucleophosmin interacts with FOXM1
and modulates the level and localization of FOXM1 in human cancer cells. J. Biol.
Wang M and Gartel AL. The suppression of FOXM1 and its targets in breast cancer xenograft
tumors by siRNA. Oncotarget. 2(12):1218-
Halasi M and Gartel AL. Suppression of FOXM1 sensitizes human cancer cells to cell death induced by DNA damage. PLoS One. 7(2):e31761, 2012.
Wang M, Halasi M, Kabirov K, Banerjee A, Landolfi J, Lyubimov AV and Gartel AL. Combination
treatment with bortezomib and thiostrepton is effective against tumor formation in
mouse models of DEN/PB-