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Patricia W. Finn, MD. Department Chair

© Copyright 2014 The Board of Trustees of the University of Illinois

Israel (Rudi) Rubinstein, M.D.

Academic Title: Professor of Medicine

Administrative Positions: Medical Director, MICU, JBVAMC; Medical Director, Center for Narcolepsy, Sleep and Health Research, UIC

Division: Pulmonary, Critical Care, Sleep and Allergy Medicine

Location: 840 S. Wood St., CSB 913-N (MC 719), Chicago, IL 60612

Phone: (312) 996-8039  Fax: (312)996-4665



MD, Hebrew University - Hadassah School of Medicine, Jerusalem, Israel (1977)

Resident, The Chaim Sheba Medical Center, Tel-Hashomer, Israel (1981-1984)

Fellow, University of Toronto, Toronto, Canada (1985-1987)

Fellow, University of California, San Francisco, CA (1987-1989)

Faculty Positions:

Clinical Specialties

Research Interests

Selected Publications

  1. Onyüksel H, Sethi V, Weinberg GL, Dudeja PK and Rubinstein I. Bupivacaine, but not lidocaine, disrupts cardiolipin-containing small biomimetic unilamellar liposomes. Chem. Biol. Interact. 20;169(3):154-9, 2007.
  2. Lim SB, Rubinstein I and Onyüksel H. Freeze drying of peptide drugs self-associated with long-circulating, biocompatible and biodegradable sterically stabilized phospholipid nanomicelles. Int J Pharm. 22;356(1-2):345-50, 2008.
  3. Onyüksel H, Mohanty PS and Rubinstein I. VIP-grafted sterically stabilized phospholipid nanomicellar 17-allylamino-17-demethoxy geldanamycin: a novel targeted nanomedicine for breast cancer. Int. J. Pharm. 5;365(1-2):157-61, 2009.
  4. Sadikot RT and Rubinstein I. Long-acting, multi-targeted nanomedicine: addressing unmet medical need in acute lung injury. J. Biomed. Nanotechnol. 5(6):614-9, 2009.
  5. Gao XP and Rubinstein I. E. coli lipopolysaccharide attenuates adenosine A(1) receptor-mediated increase in plasma exudation from the hamster cheek pouch. Inflamm. Res. 60(2):195-201, 2011.
  6. Famuyiwa F and Rubinstein I. Chronic sinopulmonary inflammatory diseases in adults with undetectable serum IgE in inner-city Chicago: a preliminary observation. Lung. 190(3):291-4, 2012.
  7. Rubinstein I and Weinberg GL. Nanomedicines for chronic non-infectious arthritis: the clinician's perspective. Nanomedicine. 8 Suppl 1:S77-82, 2012.
  8. Krishnamoorthy V, Hiller DB, Ripper R, Lin B, Vogel SM, Feinstein DL, Oswald S, Rothschild L, Hensel P, Rubinstein I, Minshall R and Weinberg GL. Epinephrine induces rapid deterioration in pulmonary oxygen exchange in intact, anesthetized rats: a flow and pulmonary capillary pressure-dependent phenomenon. Anesthesiology.117(4):745-54, 2012.
  9. Dagar A, Kuzmis A, Rubinstein I, Sekosan M and Onyuksel H. VIP-targeted Cytotoxic Nanomedicine for Breast Cancer. Drug Deliv. Transl. Res.1;2(6):454-462, 2012.
  10. Fettiplace MR, Ripper R, Lis K, Lin B, Lang J, Zider B, Wang J, Rubinstein I and Weinberg G. Rapid Cardiotonic Effects of Lipid Emulsion Infusion. Crit. Care Med. 2013. Epub ahead of print.