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University of Illinois College of Medicine at Chicago >> Education, Departments & Programs >> Departments >> Research >> Ravinder K Gill, PhD

Ravinder K. Gill, Ph.D.


Academic Title: Assistant Professor of Medicine                                                                                        

Administrative Positions:

Division: Gastroenterology and Hepatology

Location: 820 S. Damen Ave., Chicago, IL 60612

Phone: (312) 569-7463 (Office) Fax: (312)-569-6487

E-mail: rgill@uic.edu





Education:

PhD, Panjab University, Chandigarh, India (2000)


Faculty Positions:


Clinical Interests


Research Interests


Selected Publications

1. Gill RK, Saksena S, Syed IA, Tyagi S, Alrefai WA, Ramaswamy K and Dudeja PK. Regulation of NHE-3 by Nitric Oxide in Caco2 Cells. Am. J. Physiol. Gastrointest. Liver Physiol 283(3) G47-G756, 2002.

2. Gill RK, Saksena S, Alrefai WA, Sarwar Z, Goldstein JL, Carroll RE, Ramaswamy K and Dudeja PK. Expression and membrane localization of MCT isoforms along the length of the human intestine. Am. J. Physiol. Cell Physiol. 289(4):C846-52, 2005.

3. Gill RK, Saksena S, Tyagi S, Alrefai WA, Malakooti J, Sarwar, Z, Turner JR, Ramaswamy K and Dudeja PK. Serotonin regulates Na+/H+ exchange in Caco2 Cells by causing tyrosine phosphoryaltion of PLCg1 and activation of PKCa. Gastroenterology. 128 (4): 962-74, 2005.

4. Gill RK, Borthakur A, Hodges K, Saksena S, Turner J, Ramaswamy K, Hecht GA and Dudeja PK. Mechanisms underlying inhibition of apical Cl-/OH- exchange by Enteropathogenic E. coli. J. Clinical Investigation. 117(2): 428-37, 2007.

5. Gill RK, Pant N, Saksena S, Tyagi S, Alrefai WA, Dwivedi A, Ramaswamy K and Dudeja PK. Expression and Functional characterization of the enteric serotonin transporter (SERT) in the human intestine. Am. J. Physiol. 294(1): G254-62, 2008.  

6. Gill RK, Le Shen, Turner JR, Saksena S, Alrefai WA, Dwivedi A, Esmaili A, Ramaswamy K and Dudeja PK. Serotonin modifies actin cytoskeleton in human intestinal epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 295(4):G700-8, 2008.

7. Borthakur A, Gill RK, Tyagi S, Koutsouris A, Alrefai WA, Ramaswamy K, Hecht GA and Dudeja PK. The probiotic Lactobacillus acidophilus stimulates chloride hydroxyl exchange activity in human intestinalepithelial cells. J. Nutrition. 138: 1355–1359, 2008.

8. Walker NM, Simpson JE, Yen PF, Gill RK, Rigsby EV, Brazill JM, Dudeja PK, Schweinfest CW and Clarke LL. Down-regulated in adenoma Cl/HCO3 exchanger couples with Na/H exchanger 3 for NaCl absorption in murine small intestine. Gastroenterology. 135(5):1645-1653.e3, 2008.  

9. Walker NM, Simpson JE, Brazill JM, Gill RK, Dudeja PK, Schweinfest CW and Clarke LL. Role of Down-Regulated in Adenoma Anion Exchanger in HCO(3)(-) Secretion Across Murine Duodenum. Gastroenterology. 136(3):893-901, 2009.

10. Bhattacharyya S, Gill R, Chen ML, Zhang F, Linhardt RJ, Dudeja PK and Tobacman JK. Toll- like receptor 4 mediates induction of Bcl10-NFkappa B-IL-8 inflammatory pathway by Carrageenan in human intestinal epithelial cells. J. Biol. Chem. 283(16):10550-8, 2008.

11. Esmaili A, Nazir SF, Borthakur A, Yu D, Turner JR, Saksena S, Singla A, Hecht GA, Alrefai WA and Gill RK. Enteropathogenic Escherichia coli infection inhibits intestinal serotonin transporter function and expression. Gastroenterology. 137(6):2074-83, 2009.

12. Bhattacharyya S, Gill R, Chen ML, Zhang F, Linhardt RJ, Dudeja PK and Tobacman JK. B-cell CLL/lymphoma 10 (BCL10) is required for NF-kappaB production by both canonical and noncanonical pathways and for NF-kappaB-inducing kinase (NIK) phosphorylation. J. Biol. Chem. 285(1):522-30, 2010.

13. Gill RK, Anbazhagan AN, Esmaili A, Kumar A, Nazir S, Malakooti J, Alrefai WA and Saksena S. Epidermal Growth Factor Up-regulates Serotonin Transporter in Human Intestinal Epithelial Cells via Transcriptional Mechanisms. Am. J. Physiol. Gastrointest. Liver Physiol. 300(4):G627-36, 2011.

14. Gill RK and Dudeja PK. A novel facet to consider for the effects of butyrate on its target cells: Focus on "The short chain fatty acid butyrate is a substrate of BCRP." Am. J. Physiol. Cell Physiol. 301(5):C977-9, 2011.

15. Namachivayam K, Blanco CL, Mohankumar K, Jagadeeswaran R, Vasquez M, McGill- Vargas L, Garzon SA, Jain SK, Gill RK, Freitag NE, Weitkamp JH, Seidner SR and Maheshwari A. Smad7 Inhibits Autocrine Expression of TGF-b2 in Intestinal Epithelial Cells in Baboon Necrotizing Enterocolitis. Am. J. Physiol. GI. Physiol. 304(2):G167-80, 2012.

16. Gill RK, Kumar A, Malhotra P, Maher D, Singh V, Alrefai WA, Dudeja PK and Saksena S. Regulation of Intestinal Serotonin Transporter (SERT) Expression via Epigenetic Mechanisms: Role of HDAC2. Am. J. Physiol. Cell Physiol. 304(4):C334-41, 2013.

17. Saksena S, Priyamvada S, Kumar A, Akhtar M, Soni V, Anbazhagan AN, Alakkam A, Alrefai WA, Dudeja PK and Gill RK. Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 304(6):G615-22, 2013.