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Patricia W. Finn, MD. Department Chair

© Copyright 2014 The Board of Trustees of the University of Illinois

Roberto F. P. Machado, M.D.

Academic Title: Associate Professor of Medicine

Administrative Positions: Director, Pulmonary Hypertension Clinic

Division: Pulmonary, Critical Care, Sleep and Allergy Medicine

Location: 909 S. Wolcott Ave., COMRB 3133 (MC 719), Chicago, IL 60612

Phone: (312)355-5894 (Office) Fax: (312)996-7193



MD, Universidade Federal do Rio Grande do Sul, Brazil (1993)

Intern, University of Miami, Miami, FL (1996-1997)

Resident, University of Miami, Miami, FL (1997-2000)

Fellow, Cleveland Clinic Foundation, Cleveland, Ohio (2000-2003)

Fellow, National Institutes of Health, Bethesda, MD (2003-2004)

Faculty Positions:

Clinical Specialties

Research Interests

Selected Publications

  1. Barnett CF, Hsue PY and Machado RF. Pulmonary hypertension: an increasingly recognized complication of hereditary hemolytic anemias and HIV infection. JAMA. 299(3):324-31, 2008.
  2. Nathan SD, Shlobin OA, Ahmad S, Barnett SD, Burton NA, Gladwin MT and Machado RF. Pulmonary hypertension in patients with bronchiolitis obliterans syndrome listed for retransplantation. Am. J. Transplant. 8(7):1506-11, 2008.
  3. Machado RF and Gladwin MT. Pulmonary hypertension in hemolytic disorders: pulmonary vascular disease: the global perspective. Chest. 137(6 Suppl):30S-38S, 2010.
  4. Machado RF, Barst RJ, Yovetich NA, Hassell KL, Kato GJ, Gordeuk VR, Gibbs JS, Little JA, Schraufnagel DE, Krishnamurti L, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Onyekwere O, Castro OL, Sachdev V, Waclawiw MA, Woolson R, Goldsmith JC and Gladwin MT; walk-PHaSST Investigators and Patients. Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood. 118(4):855-64, 2011.
  5. Vij R and Machado RF. Pulmonary complications of hemoglobinopathies. Chest. 138(4):973-83, 2010.
  6. Machado RF, Hildesheim M, Mendelsohn L, Remaley AT, Kato GJ and Gladwin MT. NT-pro brain natriuretic peptide levels and the risk of death in the cooperative study of sickle cell disease. Br. J. Haematol. 154(4):512-20, 2011.
  7. Gladwin MT and Machado RF. Pulmonary hypertension in sickle cell disease. N. Engl. J. Med. 365(17):1646-7; author reply 1648-9, 2011.
  8. Desai AA, Zhou T, Ahmad H, Zhang W, Mu W, Trevino S, Wade MS, Raghavachari N, Kato GJ, Peters-Lawrence MH, Thiruvoipati T, Turner K, Artz N, Huang Y, Patel AR, Yuan JX, Gordeuk VR, Lang RM, Garcia JG and Machado RF. A novel molecular signature for elevated tricuspid regurgitation velocity in sickle cell disease. Am. J. Respir. Crit. Care Med.  186(4):359-68, 2012.
  9. Sun X, Singleton PA, Letsiou E, Zhao J, Belvitch P, Sammani S, Chiang ET, Moreno-Vinasco L, Wade MS, Zhou T, Liu B, Parastatidis I, Thomson L, Ischiropoulos H, Natarajan V, Jacobson JR, Machado RF, Dudek SM and Garcia JG. Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury. Am. J. Respir. Cell. Mol. Biol. 47(5):628-36, 2012.
  10. Zhou T, Zhang W, Sweiss NJ, Chen ES, Moller DR, Knox KS, Ma SF, Wade MS, Noth I, Machado RF and Garcia JG. Peripheral blood gene expression as a novel genomic biomarker in complicated sarcoidosis. PLoS One. 7(9):e44818, 2012.
  11. Mehari A, Alam S, Tian X, Cuttica MJ, Barnett CF, Miles G, Xu D, Seamon C, Adams-Graves P, Castro OL, Minniti CP, Sachdev V, Taylor JG 6th, Kato GJ and Machado RF. Hemodynamic predictors of mortality in adults with sickle cell disease. Am. J. Respir. Crit. Care Med. 187(8):840-7, 2013.