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University of Illinois College of Medicine at Chicago >> Education, Departments & Programs >> Departments >> Research >> Xavier Llor MD PhD

Xavier Llor, M.D., Ph.D.

Academic Title: Associate Professor of Medicine

Administrative Positions: Director, Familial Gastrointestinal Cancer Unit; Founder and Executive Director, Chicago Coloretal Cancer Consortium

Division: Gastroenterology and Hepatology

Location: 840 S. Wood St., MC 716, Chicago, IL 60612

Phone: (312)413-8872 (Office) Fax: (312)413-4652



MD, Universitat Autonoma de Barcelona, Barcelona, Spain (1986)

Resident, University of Chicago/Lutheran General Hospital, Chicago, IL (1991-1994)

Fellow, University of Illinois at Chicago, Chicago, IL (1994-1997)

PhD, University of Barcelona, Barcelona, Spain (1999)

Faculty Positions:

Assistant Professor, Department of Medicine, Universitat Autonoma de Barcelona, Barcelona Spain (1997-2006)

Associate Professor of Medicine, Department of Medicine, University of Illinois at Chicago, Chicago, IL (2007-Present)

Clinical Specialties

Internal Medicine - Cancer Research

Research Interests

Molecular basis of hereditary colorectal cancer

Inherited gastrointestinal cancer syndromes in African Americans

Study of anticarcinogenic pathways of nutrients, particularly n-3 fatty acids and fiber, on colorectal cancer

Selected Publications

Sohn VR, Giros A, Xicola RM, Fluvià L, Grzybowski M, Anguera A and Llor X. Stool-fermented Plantago ovata husk induces apoptosis in colorectal cancer cells independently of molecular phenotype. Br. J. Nutr. 107(11):1591-602, 2011.

Xicola RM and Llor X. Cancer risk assessment in Lynch syndrome. Does the gene matter? JAMA. 305 (22): 2351-2352, 2011.

Bessa X, Alenda C, Paya A, Alvarez C, Iglesias M, Seoane A, Dedeu JM, Abulí A, Ilzarbe L, Navarro G, Pellise M, Balaguer F, Castellvi-Bel S, Llor X, Castells A, Jover R, Andreu M. Validation Microsatellite Path Score in a Population-Based Cohort of Patients With Colorectal Cancer. J. Clin. Onc. 29(25): 3374-80, 2011.

Llor X. When should we suspect a hereditary colorectal cancer syndrome? Clin. Gastroenterol. Hepatol. 10(4):363-7, 2012.

Xicola RM and Llor X. Methylation defects in sporadic and hereditary colorectal cancer. Gastroenterol. Hepatol. Epub ahead of print, 2012.

Giráldez MD, López-Dóriga A, Bujanda L, Abulí A, Bessa X, Fernández-Rozadilla C, Muñoz J, Cuatrecasas M, Jover R, Xicola RM, Llor X, Piqué JM, Carracedo A, Ruiz-Ponte C, Cosme A, Enríquez-Navascués JM, Moreno V, Andreu M, Castells A, Balaguer F and Castellví-Bel S; Gastrointestinal Oncology Group of the Spanish Gastroenterological Association. Susceptibility genetic variants associated with early-onset colorectal cancer. Carcinogenesis. Mar;33(3):613-9, 2012

Fernandez-Rozadilla C, Cazier JB, Moreno V, Crous-Bou M, Guinó E, Durán G, Lamas MJ, López R, Candamio S, Gallardo E, Paré L, Baiget M, Páez D, López-Fernández LA, Cortejoso L, García MI, Bujanda L, González D, Gonzalo V, Rodrigo L, Reñé JM, Jover R, Brea-Fernández A, Andreu M, Bessa X, Llor X, Xicola R, the EPICOLON consortium, Palles C, Tomlinson I,18, Castellví-Bel, Castells A, Ruiz-Ponte C and Carracedo A. Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration. Pharmacogenomics J. Epub ahead of print, 2012.

Fernandez-Rozadilla C, Brea-Fernández A, Bessa X, Alvarez-Urturi C, Abulí A, Clofent J, Payá A; The EPICOLON Consortium, Jover R, Xicola R, Llor X, Andreu M, Castells A, Carracedo A, Castellví-Bel S and Ruiz-Ponte C. BMPR1A mutations in early-onset colorectal cancer with mismatch repair proficiency. Clin. Genet. Epub ahead of print, 2012.

Castellví-Bel S, Ruiz-Ponte C, Fernádez-Rozadilla C, Abulí A, Muñoz J, Bessa X, Brea-Fernández A, Ferro M, Giráldez MD, Xicola RM, Llor X, Jover R, Piqué JM, Andreu M, Castells A and Carracedo A; for the Gastrointestinal Oncology Group of the Spanish Gastroenterological Association. Seeking genetic susceptibility variants for colorectal cancer: the EPICOLON consortium experience. Mutagenesis. 27(2):153-159, 2012.

Antelo M, Balaguer F, Shia J, Shen Y, Hur K, Moreira L, Cuatrecasas M, Bujanda L, Giraldez MD, Takahashi M, Cabanne A, Barugel ME, Arnold M, Roca EL, Andreu M, Castellvi-Bel S, Llor X, Jover R, Castells A, Boland CR and Goel A. A High Degree of LINE-1 Hypomethylation Is a Unique Feature of Early-Onset Colorectal Cancer. PLoS One. 7(9):e45357, 2012.