Changing Medicine for Good

Age-related eye disease
Age-related macular and retinal degeneration
Corneal disease
Diabetic maculcar edema
Diabetic retinopathy
Glaucoma
Keratoconus
Neuro-ophthalmology
Retinal vein occlusion
Retinopathy of prematurity
Uveitis

Clinical Trials Coordinators for Retina and Uveitis

Misel Ramirez
1855 W. Taylor St., Room 1.65
Chicago, IL 60612
312-996-4747
312-996-5702 (fax)
misel@uic.edu

Marcia Niec
1855 W. Taylor St., Room L135
Chicago, IL 60612
312-355-3743
312-413-7929 (fax)
mniec@uic.edu

Age-related eye disease

Age Related Eye Disease Study 2 (AREDS2) PI
Lawrence J. Ulanski, MD

Age-related macular degeneration

A Multicenter, Randomized, Single-masked Study Comparing Reduced-fluence Visudyne-Lucentis Combination Therapies and Lucentis Monotherapy in Subjects with CNV Secondary to AMD (RADICAL)
Jennifer Lim, MD

Ranibizumab Therapy for Choroidal Neovascularization Associated with Angoid Streaks
Jennifer Lim, MD

Treatment of Neovascular Glaucoma with Intravitreal Bevacizumab
Michael Blair, MD

Posurdex Retinal Vein Occlusion
Lawrence Ulanski, MD

Measuring Reading Rehabilitation Outcomes
Department of Vetrans Affairs
Rehabilitation Research and Development Service
Janet Szlyk, PhD

Nighttime Simulator Driving with Ophthonix Wavefront Aberration Spectacles
Janet Szlyk, PhD
Sponsored by Ophthonix Inc

Comprehensive Functional Assessment Of The iZON Wavefront Guided Glasses
Janet Szlyk, PhD
Sponsored by Ophthonix Inc

Age-Related Eye Disease Study II
Lawrence Ulanski, MD
Sponsored by National Institutes of Health (NIH)

An Open-Label, Dose Escalation Study of the Safety and Tolerability of 20089 (Triamcinolone Acetonide Intravitreal Injection) in the Treatment of Patients with Cystoid Macular Edema Associated with Retinal Vein Occlusion or Cataract Surgery (ICON) PI
Jennifer I. Lim, MD

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Corneal disease

Cornea Donor Study (CDS)
Joel Sugar, MD
Sponsored by Rheumatology Research, International

A Multicenter, Double-masked, Randomized, Vehicle-controlled, Parallel-group
Joel Sugar, MD
Sponsored by National Eye Institute, JAEB Center for Health Research, Inc.

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Diabetic macular edema

Study of an Experimental Drug Delivery System in the treatment of subjects with Diabetic Macular Edema
Lawrence Ulanski, MD
Sponsored by Allergan, Inc

Intravitreal Ranibizumab or Triamcinolone Acetonide as Adjunctive Treatment to Panretinal Photocoagulation for Proliferative Diabetic Retinopathy (NIH)
Jennifer Lim, MD

An Open-Label, Dose Escalation Study of the Safety and Tolerability of 20089 (Triamcinolone Acetonide Intravitreal Injection) in the Treatment of Patients with Cystoid Macular Edema Associated with Retinal Vein Occlusion or Cataract Surgery
Jennifer Lim, MD

A Randomized, Double-Mask, Placebo-Controlled, Dose-Response, Phase 2 Study of the Safety and Efficacy of Thymosin Beta 4 in the Treatment of Diabetic Patients' Corneal Wounds Resulting from Epithelial Debridement During Vitrectomy
Jennifer Lim, MD

Posurdex Diabetic Macular Edema
Lawrence Ulanski, MD

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Diabetic Retinopathy

Intravitreal Ranibizumab or Triamcinolone Acetonide as Adjunctive Treatment to Panretinal Photocoagulation for Proliferative Diabetic Retinopathy (DRCR Protocol-J) PI
Jennifer I. Lim, MD

A Randomized, Double-Mask, Placebo-Controlled, Dose-Response, Phase 2 Study of the Safety and Efficacy of Thymosin Beta 4 in the Treatment of Diabetic Patients' Corneal Wounds Resulting from Epithelial Debridement During Vitrectomy (RegeneRx) PI
Jennifer I. Lim, MD

A 3 Year, Phase 3, Multicenter, Masked, Randomized, Sham Controlled Trial to Assess the Safety and Efficacy of 700μg and 350μg Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator System in the Treatment of Patients with Diabetic Macular Edema (Posurdex DME) PI
Lawrence J. Ulanski, MD

Intravitreal Ranibizumab or Triamcinolone Acetonide in Combination with Laser Photocoagulation for Diabetic Macular Edema (DRCR Protocol-I) PI
Michael P. Blair, MD

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Glaucoma

Randomized Controlled Trial of Lucentis in the Management of New Onset Neovascular Glaucoma PI
Michael P. Blair, MD

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Keratoconus

CLEK Study Corneal Topography Reading Center
Timothy McMahon, OD
Sponsored by National Eye Institute

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Neuro-Ophthalmology

Longitudinal Ocular Neuritis Study
Participating Clinical Center
James Goodwin, MD

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Retinal vein occlusion

Study of an Experimental Drug Delivery System the treatment of subjects with Macular Edema following Central Retinal Vein Occlusion or Branch Retinal Vein Occlusion
 Lawrence Ulanski, MD
Sponsored by Allergan, Inc

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Retinopathy of prematurity

Early Treatment of Retinopathy of Prematurity
Participating Clinical Center
Michael Shapiro, MD

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Uveitis

Multi-Center Uveitis Steroid Treatment (MUST) Trial
 Debra Goldstein, MD
Sponsored by National Eye Institute (NEI)

An Open-Label, Multicenter, Phase II Trial of Adalimumab (Humira) in the Treatment of Refractory Non-infectious Uveitis
Debra Goldstein, MD
Sponsored by Abbott

Study of an Experimental Drug Delivery System in the treatment of Non- infectious Ocular Inflammation of the Posterior Segment in Subjects with Intermediate Uveitis
 Howard Tessler, MD
Sponsored by Allergan, Inc

Study of an Experimental Drug Delivery System in the treatment of Non Infectious Ocular Inflammation of the Anterior Segment in Subjects with Anterior Uveitis
Howard Tessler, MD
Sponsored by Allergan, Inc

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