Macular Hole
Macular holes may be caused by eye injuries, certain eye disease, and eye inflammation, but generally result from the normal aging process. Vitreous is firmly attached to the central portion of the retina (the macula) as the vitreous shrinks, as it does with normal aging, and moves a hole can be formed at the macula.
Signs and Symptoms
- Decreased central vision for both distance and reading activities
- Distortion in central vision, a small defect in the central vision where small letters may disappear
- Distorted "wavy" or blurred central vision
- Central gray area or blind spot in more severe cases
- Spontaneous, partial or total loss of sharp, central vision
Treatments and Prevention
- Vitrectomy
UIC Specialists
Jennifer Lim, MD
Norman Blair, MD
Michael Shapiro, MD
Any Vitreoretinal Specialist
Treatment Clinic/Service
Vitreoretinal Service
Clinical Treatment and Trials
A Multicenter, Randomized, Single-masked Study Comparing Reduced-fluence Visudyne-Lucentis Combination Therapies and Lucentis Monotherapy in Subjects with CNV Secondary to AMD (RADICAL)
Investigator: Jennifer Lim, MD
Sponsor: Qlt. Inc.
Ranibizumab Therapy for Choroidal Neovascularization Associated with Angoid Streaks
Investigator: Jennifer Lim, MD
Sponsor: PI Initiated.
An Experimental Approach to Maculopathy
Investigator: Jennifer Lim, MD
Sponsor: PI Initiated.
Intravitreal Ranibizumab or Triamcinolone Acetonide as Adjunctive Treatment to Panretinal Photocoagulation for Proliferative Diabetic Retinopathy
Investigator: Jennifer Lim, MD
Sponsor: NEI.
An Open-Label, Dose Escalation Study of the Safety and Tolerability of 20089 (Triamcinolone Acetonide Intravitreal Injection) in the Treatment of Patients with Cystoid Macular Edema Associated with Retinal Vein Occlusion or Cataract Surgery
Investigator: Jennifer Lim, MD
Sponsor: ICON Bioscience, Inc.
A Randomized, Double-Mask, Placebo-Controlled, Dose-Response, Phase 2 Study of the Safety and Efficacy of Thymosin Beta 4 in the Treatment of Diabetic Patients' Corneal Wounds Resulting from Epithelial Debridement During Vitrectomy
Investigator: Jennifer Lim, MD
Sponsor: RegeneRx.
This information is not intended to replace the advice of a doctor.