Scientists

Robert Chang , PhD Assistant Professor

Research Interests

Matrix metalloproteinases and anti-angiogenic factors in corneal neovascularization

Education

• 1990 Ph.D. Biochemistry, University of Mississippi Medical Center, Jackson, MS

• 1980 BS, Food Sciences, National Taiwan Ocean University, Taiwan

Employment History

• 2000-2006 Instructor of Ophthalmology, Mass Eye and Ear Infirmary, Harvard Medical School.

• 1998-1999 Instructor of Pediatrics, Dana Farber Cancer Institute, Department of Pediatric oncology, Harvard Medical School.

• 1994-1997 Postdoctoral Scientist, Dana Farber Cancer Institute, Department of Pediatric oncology, Harvard Medical School.

• 1990-1994 Postdoctoral Scientist, Department of Microbiology, University of Virginia.
  

UIC Appointments

2006-present Assistant Professor, Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago

Representative Publications

1. Albe` E, Escalona E, Rajagopal R, Javier JA, Chang JH, and Azar DT. Proteomic Identification of ALK1 as a Differentially-Expressed Protein During Hyaloid Vascular System Regression, FEBS Lett. 2005, 24;579(25):5481-6.

2. Chang JH, Javier JA, Chang GY, Oliveira HB, and Azar DT.  Functional characterization of neostatins, the MMP-derived, enzymatic cleavage products of type XVIII collagen, FEBS Lett. 2005, 4;579(17):3601-6.

3. Gabison, E.E., Chang, J.-H., Herna`ndez-Quintela, E., Lu, P.C.S., Ye, H.Q., Kure, T., Kato, T., Azar, D.T. Anti-angiogenic role of angiostatin in the cornea during wound healing. 2004, Exp Eye Res. 2004 Mar;78(3):579-89.

4. Kure T, Hernandez-Quintela H, Ye H, Lu P S-H, Jain S, Matrisian LM, Shapiro SD, Chang, J.-H and Azar DT. Corneal neovascularization after excimer keratectomy wounds in MMP-7 knockout mice. Invest Ophthalmol Vis Sci. 2003;44:137-44.

5. Kato, T., Chang, J.-H., Azar, D.T. Expression of Type XVIII collagen during Wound healing of corneal incisions and keratectomy wounds Invest Ophthalmol Vis Sci. 2003, 44:78-85.