Scientists

Beatrice Y.J.T. Yue, PhD Thanis A. Field Professor of Ophthalmology Director, Ocular Cell Biology Laboratory

Research Interests

Molecular basis for keratoconus; function of myocilin, a glaucoma gene

Education

• 1968 B.S. (Chemistry) National Taiwan University, Taipei, Taiwan

• 1969-1970 M.S. (Biochemistry) Yale University, New Haven, CT

• 1974 Ph.D. (Biological Chemistry) Washington University School of Medicine, St. Louis, MO

UIC Appointments

Professor, Department of Ophthalmology and Visual Sciences

Professor, Department of Pathology http://www.uic.edu/depts/mcpt/

Click here to visit Ocular Cell Biology Lab Site

Representative Publications

Whitelock RB, Li Y, Zhou L, Sugar J and Yue BYJT: Expression of transcription factors in keratoconus, a cornea-thinning disease. Biochem Biophys Res Commun 235:253-258, 1997.

Li Y, Zhou L, Twining SS, Sugar J and Yue BYJT: Involvement of Sp1 element in promoter activities of the a1-proteinase inhibitor gene.  J Biol Chem 273:9959-9965, 1998.

Wentz-Hunter K, Shen X, Okazaki K, Tanihara H and Yue BYJT: Overexpression of myocilin in cultured human trabecular meshwork cells.  Exp Cell Res 297:39-48, 2004.

Nakamura H, Siddiqui SS, Shen X, Malik AB, Pulido JS, Kumar NM and Yue BYJT: RNA interference targeting transforming growth factor-² type II receptor suppresses ocular inflammation and fibrosis.  Mol Vis 10:703-711, 2004.

Yue BYJT: Cellular mechanisms in the trabecular meshwork affecting aqueous humor outflow pathway.  In: Principles and Practice of Ophthalmology.  2^nd edition.  Albert D and Jakobiec F, editors.  W.B. Sauders Co., Philadelphia, PA.  Vol. 4, pp 2596-2613, 1999.

Click here to view Dr. Yue’s abbreviated on-line CV