Scientists
 |
Thanis A. Field Professor of Ophthalmology |
| beatyue@uic.edu | |
| Phone | 312-996-6125 |
| Fax | 312-996-7773 |
| Office | LIERI Building, Room 243 |
| Address | University of Illinois at Chicago Department of Ophthalmology and Visual Sciences 1855 W. Taylor Street M/C 648 Chicago, IL 60612 |
Research Interests
Molecular basis for keratoconus; characterization and functions of glaucoma genes
Education
- 1968 B.S. (Chemistry) National Taiwan University, Taipei, Taiwan
- 1969-1970 M.S. (Biochemistry) Yale University, New Haven, CT
- 1974 Ph.D. (Biological Chemistry) Washington University School of Medicine, St. Louis, MO
- Professor, Department of Ophthalmology and Visual Sciences
- Professor, Department of Pathology
Representative Publications
Shen X, Koga T, Park BC, SundarRaj N and Yue BYJT: Rho GTPase and cAMP/PKA signaling mediates myocilin induced alterations in cultured human trabecular meshwork cells. J Biol Chem 283:603-612, 2008.
Sakai H, Shen X, Koga T, Park BC, Noskina Y, Tibudan M and Yue BYJT: Mitochondrial association of myocilin in human trabecular meshwork cells. J Cell Physiol 213:775-784, 2007.
Park BC, Shen X, Samaraweera M and Yue BYJT: Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild type and mutant optineurin in two ocular cell types. Am J Pathol 169:1976-1989, 2006.
Nakamura H, Siddiqui SS, Shen X, Malik AB, Pulido JS, Kumar NM and Yue BYJT: RNA interference targeting transforming growth factor- type II receptor suppresses ocular inflammation and fibrosis. Mol Vis 10:703-711, 2004.
Maruyama Y, Wang X, Li Y, Sugar J and Yue BYJT: Involvement of Sp1 element in the promoter activity of genes affected in keratoconus. Invest Ophthalmol Vis Sci 42:1980-1985, 2001.