|
Campus Address
Rm
2171 University of Illinois
Hospital
1740 West Taylor Street
Chicago, Illinois
60612
Clinical & Research
Interests
alpha-1
antitrypsin deficiency in homozygotes and symptomatic heterozygotes,
COPD,
interstitial
lung disease including
novel therapies for idiopathic pulmonary fibrosis and anti-TNF
antibody strategies in Sarcoidosis
Alternate
strategies for sedation in ventilated patients
Clinical
Services
Fiberoptic bronchoscopy including diagnostic
and therapeutic procedures including argon-plasma and cryo intraluminal
ablation, stent placements
Pulmonary function testing
Bronchoprovocational testing
Outpatient Pulmonary
diagnostic and therapeutic clinics
Critical Care Medicine
Special
Interests
Alpha-1
antitrypsin deficiency, COPD, interstitial lung disease, critical
care medicine, interventional bronchoscopy
Clinic
Schedule
Tues:
1-5 (Arlington
Heights)
Wednesday 1-5 (Jesse
Brown Veterans
Administration Hospital)
Thursday 8-12 UIMC Outpatient Care Center
Contact
Info for Appointments
Call
Arlington Heights: (847) 690-0727
Jesse Brown VAH: (312) 569-6906
UIMC Outpatient Care
Center (312) 996-1682
Professional
Background
2000-Present
Associate Professor, Section of Pulmonary, Critical Care
and Sleep Medicine, Department of Medicine, University of Illinois
at Chicago (UIC), Chicago, IL
1993-2000
Assistant Professor, Section of Respiratory and Critical
Care Medicine, Department of Medicine and Department of Genetics,
UIC, Chicago, IL
1986-1993
Senior Staff Fellow, Division of Intramural Research,
National Heart Lung and Blood Institute, Bethesda,
MD
1977-1979
National Cancer Institute Summer Research Associate and
Toxicology Technician and Phlebotomist, Georgetown
University Hospital, Washington,
DC
1976-1977
Research Technician, Department of Immunoparasitology,
Naval Medical Research Institute and Department of Medicine,
Uniformed University of the Health Sciences, Bethesda, MD
1975-1976
Tissue Culture Technician, Department of Pharmacology,
George Washington University Medical Center, Washington DC
EDUCATION
AND TRAINING
1984-1986 Postdoctoral Fellow, Division of Respiratory Medicine,
Department of Medicine, Johns Hopkins School of Medicine, Baltimore,
MD
1981-1984 Intern, Junior and Senior Resident, Osler
Medical Service, Johns
Hopkins Hospital,
Baltimore,
MD
1977-1981 Medical Student, Georgetown University Medical
School
1969-1975 BA Biology: Undergraduate Student,
University of Rochester, Rochester
NY
Personal
Interests and accomplishments
Active in Congregation Beth Shalom
Married
and father of 2 sons
Active
member of Congregation Beth Shalom
Avid
reader
Clinical
Research
interests include:
anti-neutrophil
elastase screen in alpha-1 antitrypsin heterozogotes
Prevalence
of alpha-1 antitrypsin in the Veterans
Administration Hospital Population
Novel
therapies for idiopathic pulmonary fibrosis
Anti-TNF
alpha strategies in Sarcoidosis
The
efficacy of anti-IgE strategies in severe, steroid-dependent
asthma
The
role of atopy and immunoglobin E in COPD
Alternate
strategies for sedation in ventilated patients
Representative
Publications
Panepinto
J, Liu, L Ramos J, Xhu X, Valyi-Nagy T, Eksi S, Fu J, Jaffe
HA, Wickes B, Williamson PR. 1,5 The DEAD-box RNA helicase
Vad1 regulates multiple virulence-associated genes in Cryptococcus
neoformans. J. Clin.
Invest. 115(3):632-641, 2005.
Ramirez
AM, Takagawa S, Sekosan M. Jaffe HA, Varga J, Roman J. Smad3 deficiency
ameliorates experimental obliterative bronchiolitis in a heterotopic
tracheal transplantation model. American Journal of Pathology. 165(4):1223-32, 2004.
Pechkovsky
DV, Zissel G, Jaffe HA, Stamme C, Einhaus M, Taube C, Magnussen H, Schlaak M,
Müller-Quernheim J Human
alveolar epithelial cells type II induce nitric oxide synthase-2
expression in alveolar macrophages by an interferon-gamma-dependent
pathway. European Respiratory Journal
19:672-83, 2002
Mack
DG, Jaffe HA.
Effect of admiminstration of a recombinant adenovirus expressing
the genes for interferon-g and
interleukin-12 on acute murine toxoplasmosis. J Interferon & Cytokine Res 21:777-783,
2001.
Jaffe
HA, Gao ZC, Mori Y, Li-Ye L, Varga J. Selective inhibition of collagen gene expression in fibroblasts
by and interferon-g transgene. Exp
Lung Res 25:199-215, 1999
MEDLINE
LINK
|
