Campus Address
1740 W Taylor St (Medical Center Building)
Chicago, Illinois 60612-7323
cosolopa@uic.edu

Clinical & Research Interests
Clinical
Asthma
Obstructive Lung Diseases
Sleep Disorders

Research
Impact of compromised cerebral blood flow in OSA on cognitive performance
Environmental and genetic influences on asthma expression
Health Policy implication of obesity and health disparities

Clinical Services
Highly specialized bronchoscopy services, including fiberoptic bronchoscopy
Pulmonary function testing
Bronchoprovocational testing
Cardiopulmonary exercise testing
Overnight polysomnography
Multiple sleep latency tests

Special Interests
Asthma, obstructive lung diseases and sleep disorders;

Clinic Schedule
Tues: 1-5
Thursday and Friday (alternating weekly): 9-1, 1-5

Contact Info for Appointments
Call 312-996-1682 - scheduling.

Professional Background
Academic Appointments
1988-1991
Clinical Fellow in Medicine, Mayo Clinic, Rochester, Minnesota

1989-1991
Clinical Instructor in Medicine, Mayo Medical School, Rochester, Minnesota

1991 to 1997
Assistant Professor of Medicine,
University of Illinois at Chicago, Chicago, IL

1997
Associate Professor of Medicine
University of Illinois at Chicago, Chicago, IL
Hospital Appointments

1991 to date
Attending Physician, University of Illinois Hospital, Chicago, IL

1991-1993
Director, Respiratory Therapy,
West Side VA Medical Center, Chicago, IL
Deputy Chief, Section of Respiratory and Critical Care
Medicine, West Side VA Medical Center, Chicago, IL

1993 to date
Director, Asthma Clinical Research, University of Illinois,
Chicago, Chicago, IL

1995 to 1996
Physician Advisor, Utilization Management,
University of Illinois Hospital, Chicago, IL

1996 to 2000
Director, Pulmonary Outpatient Services,
University of Illinois at Chicago, Chicago, IL

1996 to 1999
Director, Respiratory Services,
Vencor Hospital of Chicago, Chicago, IL

2000 to 2004
Medical Director, Center for Sleep and Ventilatory Disorders,
University of Illinois at Chicago, Chicago, IL

EDUCATION AND TRAINING
1975-80 University of Ibadan, Nigeria. M.B.B.S
2003-2005 University of Illinois at Chicago School of Public Health
MPH (Health Policy and Administration).

Internship and Residencies
1980-1981 Rotating Internship, University College Hospital, Ibadan, Nigeria.
1984-1985 Intern in Medicine, Cook County Hospital, Chicago, IL
1985-1986 Resident in Medicine, Cook County Hospital, Chicago, IL
1986-1987 Chief Medical Resident, Cook County Hospital, Chicago, IL

Fellowship
1988-1991 Division of Thoracic Diseases, Mayo Graduate School of
Medicine, Mayo Clinic, Rochester, Minnesota

Personal Interests and accomplishments
Outside of my work at the University, my personal interests include leadership and capacity building efforts to support Higher Education in Nigeria. I currently serve as the President of The Nigeria Higher Education Foundation, a MacArthur supported Foundation based in New York, charged with the responsibility of making the case for support of higher education in 4 designated Institutions in Nigeria (www.thenhef.org link for details).
I am also the Founder and President of Healthy Life for All Foundation (www.hlfonline.org), a Non Governmental Foundation based in Nigeria with the objectives of promoting healthy lifestyles, capacity building through technology transfer and collaborative research, development of a clinical trial infrastructure and to develop private/public partnership in achieving the aforementioned goals.
I have 3 wonderful children and love to travel and bike. I played cricket for Nigeria decades ago

Clinical Research
My research in asthma focuses on the determination of appropriate or best practice for asthma management through collaborative and multi-center clinical research projects as part of the American Lung Association designated Asthma Clinical Research Centers.
I am also interested in the relationship between environmental and genetic factors on the expression of asthma especially in a developing country setting such as Nigeria, focusing on regional differences between rural and urban settings and ultimately comparing to similar settings in inner city Chicago

My research work in Sleep deals with the understanding of the impact of compromised cerebral blood flow (using near infra-red spectroscopy) and intermittent hypoxemia, which characterizes obstructive apnea events in OSA on cognitive function and performance.

Representative Publications
Olopade CO, Staats BA. Time course of recovery from "Frost Bitten Phrenics" following Coronary Artery Bypass Graft Surgery. Chest 1991, 99: 1112-1115.

Olopade CO, Viggiano RW, Beck KC, Staats BA. Exercise limitation and pulmonary rehabilitation in COPD. Mayo Clin Proc 1992, 67:144-157.

Olopade CO, Crotty TB, Douglas WW, Colby TV, Sur S. Chronic eosinophilic pneumonia and idiopathic bronchiolitis obliterans organizing pneumonia: comparison of eosinophil number and degranulation by immunofluorescence staining for eosinophil major basic protein. Mayo Clin Proc 1995, 70: 137-142.

Gao X-p, Suzuki H, Olopade CO, Rubinstein I. Short-term exposure to lipopolysaccharide is associated with microvascular contractile dysfunction in vivo. Life Sci 1995, 56(15): 1243-49

Gao X-p, Jaffe HA, Olopade CO, Rubinstein I. Stable VIP analogue Ro-24-9981, potentiates substance P-induced plasma exudation in hamster cheek pouch. J Appl Physio 1995, 79(3):968-974.

Suzuki H, Gao X-p, Olopade CO, Jaffe HA, Pakhlevaniants S, Rubinstein I. Aqueous smokeless tobacco extract impairs endothelium-dependent vasodilation in the oral mucosa. J Appl Physio 1996, 81(1): 225-231.

Suzuki H, Gao X-p, Olopade CO, Rubinstein I. Neutral endopeptidase modulates VIP-induced vasodilatation in hamster cheek pouch vessels in situ. Am J Physio 1996, 271: R393-R397.

Sekosan M, Zakkar M, Wenig B, Olopade CO, Rubinstein I. Inflammation is in the uvula mucosa of patients with obstructive sleep apnea. Laryngoscope 1996, 106: 1018-1020.

Gao X-p, Vishwanatha JK, Conlon JM, Olopade CO, Jaffe HA, Rubinstein I. Mechanisms of smokeless tobacco-induced buccal mucosa inflammation: role of bradykinin. J Immunol 1996, 157: 4624-4633

Zakkar M, Sekosan M, Wenig B, Olopade CO, Rubinstein I. Immunoreactive neutral endopeptidase is decreased in uvula epithelium of patients with obstructive sleep apnea. Ann Otol Rhinol and Laryngol 1997, 106: 474-477.

Olopade CO, M Zakkar, Swedler WI, Rubinstein I. Exhaled pentane levels in acute asthma. Chest 1997, 111: 862-865

Olopade CO, Christon JA, Zakkar M, Hua C-w, Swedler WI, Scheff PA, Rubinstein I. Exhaled pentane and nitric oxide levels in patients with obstructive sleep apnea. Chest 1997, 111:1500-1504.

Gao X-p, Suzuki H, Pakhlevaniants S, Olopade CO, Rubinstein I. Purified ACE attenuates smokeless tobacco induced macromolecular efflux from the oral mucosa. J Appl Physio 1997, 83: 74-81.

Gao X-p, Suzuki H, Olopade CO, Pakhlevaniants S, Rubinstein I. Angiotensin-converting enzyme and neutral endopeptidase modulate smokeless tobacco-induced increase in macromolecular efflux from the oral mucosa in vivo. J Lab Clin Med 1997, 130: 395-400.

MEDLINE LINK