Clinic Schedule
Tues: 1-5 PM

Contact Info for Appointments
(312) 996-1682

Professional Background
1976-1982 Assistant Professor of Medicine, University of Illinois Abraham Lincoln School of Medicine, Chicago, Illinois.

1982-1989 Associate Professor of Medicine, University of Illinois at Chicago College of Medicine.

1989-Present Professor of Medicine, University of Illinois at Chicago College of Medicine.

1989-1993 Acting Chief, Section of Respiratory and Critical Care Medicine, Department of Medicine, University of Illinois at Chicago College of Medicine.

1989-2000 Program Director, Section of Respiratory and Critical Care Medicine, Department of Medicine, University of Illinois at Chicago College of Medicine.

2005-Present Director of Clinical Services, Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Illinois Medical Center at Chicago.

Hospital Appointments:
1976-Present Attending Physician, University of Illinois Medical Center at Chicago.

1976-2003 Staff Physician, Veterans Affairs Chicago Health Care System-West Side Division, Chicago, Illinois.

1976-1991 Medical Director, Respiratory Therapy Section, Department of Veterans Affairs West Side Medical Center, Chicago, Illinois.

1979-1984 Director, Sleep and Ventilatory Disorders Center, University of Illinois Medical Center at Chicago.

1989-1993 Acting Chief, Section of Respiratory and Critical Care Medicine, University of Illinois Medical Center at Chicago.

1995-2003 Associate Chief, Medical Service, Veterans Affairs Chicago Health Care System-Westside Division, Chicago, Illinois.

EDUCATION AND TRAINING
Education:
1964-1970 M.D., University of Hacettepe Medical School, Ankara, Turkey.

Postdoctoral Training:
1970-1971 Medical Resident, University of Hacettepe Hospitals, Ankara, Turkey.

1971-1972 Medical Intern, University of Louisville Hospitals, Louisville, Kentucky.

1972-1974 Medical Resident, University of Illinois Hospitals, Chicago, Illinois.

1974-1976 Fellow in Pulmonary Medicine, University of Illinois Hospitals, Chicago, Illinois.

Personal Interests and accomplishments
Awards and Honors:
1980 Best Research Paper Award, American College of Chest Physicians.

1990 The Clifford G. Pilz, M.D. House Staff Award for Attending Physician of the Year, Department of Medicine, University of Illinois at Chicago College of Medicine.

1991 Alpha Omega Alpha Honor Medical Society, University of Illinois at Chicago College of Medicine.

1996 The Academy for Excellence in Teaching, University of Illinois at Chicago College of Medicine.

1997, 1999 Listed in Best Doctors in America, ed. Woodward/White, Inc.

1998 The Clifford G. Pilz, M.D. House Staff Award for Attending Physician of the Year, Department of Medicine, University of Illinois at Chicago College of Medicine.

1999 Fellows' Attending of the Year Award, Section of Respiratory and Critical Care Medicine, Department of Medicine, University of Illinois at Chicago College of Medicine.

2001 The Clifford G. Pilz, M.D. House Staff Award for Attending Physician of the Year, Department of Medicine, University of Illinois at Chicago College of Medicine.

2002 Fellows' Attending of the Year Award, Section of Respiratory and Critical Care Medicine, Department of Medicine, University of Illinois at Chicago College of Medicine.

Clinical Research
At the present time, I am a full-time clinician/teacher.

Representative Publications
Önal E, Lopata M, Lourenço RV. Disseminated pulmonary blastomycosis in an immuno-suppressed patient: diagnosis by fiberoptic bronchoscopy. Am Rev Respir Dis 1976; 113:83-86.

Önal E, Lopata M, Lourenço RV. Nodular pulmonary sarcoidosis: clinical, roentgenographic and physiological course in five patients. Chest 1977; 72:296-300.

Lopata M, Evanich MJ, Önal E, Zubillaga G, Lourenço RV. Airway occlusion pressure and respiratory nerve and muscle activity in studies of respiratory control. Chest 1978; 73:285-286.

Lopata M, Freilich R, Önal E, Pearle J, Lourenço RV. Ventilatory control and the obesity hypoventilation syndrome. Am Rev Respir Dis 1979; 119:165-168.

Önal E, Lopata M, Evanich MJ. Effects of electrode position on esophageal diaphragmatic EMG response to CO2 rebreathing in humans. J Appl Physiol 1979; 47:1234-1238.

Lopata M, Önal E, Evanich MJ, Lourenço RV. Respiratory neuromuscular response to CO2 rebreathing with inspiratory flow resistance in humans. Respiration Physiol 1980; 39:95-110.

Organek HW, Önal E. A multifaceted approach to chronic obstructive lung disease. Drug Therapy 1980; 10:45-60.

Önal E, Lopata M, O'Connor TD. Diaphragmatic and genioglossal EMG responses to CO2 rebreathing in humans. J Appl Physiol 1981; 50:1052-1055.

Önal E, Lopata M, O'Connor TD. Diaphragmatic and genioglossal EMG responses to isocapnic hypoxia in humans. Am Rev Respir Dis 1981; 124:215-217.

Önal E, Lopata M, Ginzburg AS, O'Connor TD. Diaphragmatic EMG in studies of inspiratory "off-switch" mechanisms in humans. Lung 1981; 159:265-273.

Önal E, Lopata M, Ginzburg AS, O'Connor TD. Diaphragmatic EMG and transdiaphragmatic pressure measurements with a single catheter. Am Rev Respir Dis 1981; 124:563-565.

Önal E, Lopata M, O'Connor TD. Pathogenesis of apneas in hypersomnia-sleep apnea syndrome. Am Rev Respir Dis 1982; 125:167-174.

Lopata M, Önal E. Mass loading, sleep apnea, and the pathogenesis of obesity-hypoventilation. Am Rev Respir Dis 1982; 126:640-645.

Önal E, Lopata M. Periodic breathing and the pathogenesis of occlusive sleep apneas. Am Rev Respir Dis 1982; 126:676-680.

Önal E, Lopata M. Periodic breathing and sleep apnea. Am Rev Respir Dis 1983; 127:524-525.

Lopata M, Önal E, Ginzburg AS. Respiratory muscle function during CO2 rebreathing with inspiratory flow resistive loading. J Appl Physiol 1983: 54:475-482.

Mahadevia AK, Önal E, Lopata M. Effects of expiratory positive airway pressure on sleep-induced respiratory abnormalities in patients with sleep apnea syndrome. Am Rev Respir Dis 1983; 128:708-711.

Leech JA, Önal E, Lopata M. Recent developments in the understanding of the sleep apnea-hypersomnolence syndrome. Prac Cardiol 1984; 10:141-151.

Lopata M, O'Connor TD, Önal E. Effects of position on respiratory muscle function during CO2 rebreathing. Respiration 1985; 47:98-106.

Önal E, Leech JA, Lopata M. Relationship between pulmonary function and sleep-induced respiratory abnormalities. Chest 1985; 87:437-441.

Lopata M, Organek HW, Önal E. Comparison of magnetometer and inductive plethysmography derived Konno-Mead diagrams during CO2 rebreathing. Bull Physiopathol Respir 1985; 21:159-163.

Önal E, Leech JA, Lopata M. Dynamics of respiratory drive and pressure during NREM sleep in patients with occlusive apneas. J Appl Physiol 1985; 58:1971-1974.

Lopata M, Önal E, Cromydas G. Respiratory load compensation in chronic airways obstruction. J Appl Physiol 1985; 59:1947-1954.

Alex CG, Önal E, Lopata M. Upper airway occlusion during sleep in patients with Cheyne-Stokes respiration. Am Rev Respir Dis 1986; 133:42-45.

Önal E, Lourenço RV. Primary Alveolar Hypoventilation. In : Current Therapy of Respiratory Disease-2. Cherniack RM, ed, BC Decker Inc, Toronto. 1986, pp 269-271.

Önal E, Burrows DL, Hart RW, Lopata M. Induction of periodic breathing during sleep causes upper airway obstruction in man. J Appl Physiol 1986; 61:1438-1443.

Önal E, Lopata M. Respiratory timing during NREM sleep in patients with occlusive sleep apnea. J Appl Physiol 1986; 61:1444-1448.

Önal E, Lopata M. Respiratory muscle interaction during NREM sleep in patients with occlusive apnea. J Appl Physiol 1986; 61:1891-1895.

Alex CG, Aronson RM, Önal E, Lopata M. Effects of continuous positive airway pressure on upper airway and respiratory muscle activity. J Appl Physiol 1987; 62:2026-2030.

Leech JA, Önal E, Baer P, Lopata M. Determinants of hypercapnia in occlusive sleep apnea syndrome. Chest 1987; 92:807-813.

Aronson RM, Alex CG, Önal E, Lopata M. Changes in end-expiratory lung volume during sleep in occlusive apnea. J Appl Physiol 1987; 63:1642-1647.

Önal E. Central sleep apnea. Seminars in Respiratory Medicine 1988; 9:547-553.

Leech JA, Önal E, Dulberg C, Lopata M. A comparison of men and women with obstructive sleep apnea syndrome. Chest 1988; 94:983-988.

Lopata M, Önal E, Aronson RM, Carley DW. Effects of inspiratory loading on 31phosphorus magnetic resonance spectroscopy of the inspiratory intercostal muscles in humans. Trans Assoc Amer Physicians 1988; 101:203-211.

Aronson RM, Önal E, Carley DW, Lopata M. Upper airway and respiratory muscle responses to continuous negative airway pressure. J Appl Physiol 1989; 66:1373-1382.

Ginzburg AS, Lopata M, Önal E. Effects of loading and unloading of the respiratory system on respiratory control and muscle function. Respiration 1989; 55:16-27.

Carley DW, Önal E, Aronson RM, Lopata M. Breath by breath interactions between inspiratory and expiratory duration in occlusive sleep apnea. J Appl Physiol 1989; 66:2312-2319.

Ginzburg AS, Önal E, Aronson RM, Schild JA, Mafee MF, Lopata M. Successful use of nasal-CPAP for obstructive sleep apnea in hunter syndrome with diffuse airway involvement and hypoventilation. Chest 1990; 97:1496-1498.

Lopata M, Aronson RM, Carley DW, Önal E. Role of the genioglossus in periodic breathing during sleep. In: Sleep and Respiration. Issa FG, Remmers JE, Suratt PM, eds, Wiley-Liss Inc, New York, 1990; pp 227-232.

Aronson RM, Carley DW, Önal E, Wilborn J, Lopata M. Upper airway muscle activity and the thoracic volume dependence of upper airway resistance. J Appl Physiol 1991; 70:430-438.

Leech JA, Aronson RM, Önal E, Lopata M. Voluntary hyperventilation in obesity hypoventilation. Chest 1991; 100:1334-1338.

Boomsma JD, Önal E. Perioperative Pulmonary Assessment and Management. In: General Surgery , ed. Sayek, I. Günes Kitabevi Ltd. Sti., Ankara, Turkey. 1991; pp: 443-448.

Carley DW, Önal E, Lopata M. Quantitative analyses of state of vigilance in periodic breathing. In: Sleep and Respiration in Aging Adults. Kuna ST, Suratt PM, Remmers JE, eds, Elsevier Science Publishing Co., Inc., New York, 1991; pp 287-293.

Leech JA, Önal E, Lopata M. Nasal CPAP continues to improve sleep-disordered breathing and daytime oxygenation over long-term follow-up of occlusive sleep apnea syndrome. Chest 1992; 102:1651-1655.

Önal E. Sleep-disordered breathing in patients with end-stage renal disease. Kidney 1993; 2:309-311.

Carlson DM, Carley DW, Önal E, Lopata M, Basner RC. Acoustically induced cortical arousal increases phasic pharyngeal muscle and diaphragmatic EMG. J Appl Physiol 1994; 76:1553-1559.

Basner RC, Önal E. Dealing with the differential diagnosis of obstructive sleep apnea syndrome. Comprehensive Therapy 1994; 20:273-276.

Basner RC, Önal E, Carley DW, Stepanski EJ, Lopata M. Effect of induced transient arousal on obstructive apnea duration. J Appl Physiol 1995; 78:1469-1476.

Carlson DM, Önal E, Carley DW, Lopata M, Basner RC. Palatal muscle electromyogram activity in obstructive sleep apnea. Am J Respir Crit Care Med 1995; 152:1022-1027.

Baris B, Önal E. Lungs and surgery. In: General Surgery, ed. Sayek, I. Günes Kitabevi Ltd. Sti., Ankara, Turkey. 1996; pp: 757-763.

Carley DW, Applebaum R, Basner RC, Önal E, Lopata M. Respiratory and electrocortical responses to acoustic stimulation. Sleep 1996; 19:S189-S192.

Carley DW, Applebaum R, Basner RC, Önal E, Lopata M. Respiratory and arousal responses to acoustic stimulation. Chest 1997; 112:1567-1571.

Crisostomo I, Zayyad A, Carley DW, Abubaker J, Önal E, Stepanski EJ, Lopata M, Basner RC. Chemo- and baroresponses differ in african-americans and caucasians in sleep. J Appl Physiol 1998; 85:1413-1420.

Basner RC, Önal E. Disordered breathing during sleep. In: Rehabilitation of the Patient with Respiratory Disease. Cherniack NS, Homma I, Altose M.D., eds, McGraw-Hill, New York; 1999, pp 169-184.

Khurshid A, Barnett VT, Sekosan M, Ginzburg AS, Önal E. Disseminated pseudallescheria boydii infection in a non-immunocompromised host. Chest 1999; 116:572-574.

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