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Publications

Dr. Amelia Bartholomew

 

  • Wang, J., Pollak, R., Bartholomew, A., "Sustained Reduction of Serum Cholesterol level Following Allotransplantation of Parenchymal Hepatocytes in WHHL Rabbits."  Transplantation Proceedings, 1991; 23:894-5.

  • Powelson J, Bailin M, Bartholomew A, Boskebick S, Colvin R, Hong HZ, Johnson M, Kimikawa M, Sablinski T, Wee SL, Sachs D, Cosimi AB A mixed chimerism approach to renal transplantation between concordant nonhuman primate species.Transplant Proc 1996; 28(2):761

  • Bartholomew, A., Latinne, D., Sachs, D., Gianello, P., De Bruyere, M., Sokal, G., Squifflet, J., Alexandre,G., Comerford, C., Saidman, S., Cosimi, A. “Utility of Xenografts: Lack of Correlation between PRA and Natural Antibodies to Swine.” Xenotransplantation, 1997; 4:34-39.

  • Kimikawa, M., Kawai, T., Sachs, DH, Colvin, RB, Bartholomew, A, Cosimi,AB. “Mixed Chimerism and Transplantation Tolerance Induced by a Non-lethal Preparative Regimen in Cynomolgus Monkeys.” Transplantation Proceedings, 1997; 29:1218

  • Bartholomew, A.,Cosimi, AB, Sachs, M., Bailin, M.,Boskovic, R., Colvin, R.,Hong, H., Johnson, M.,Kimikawa, M., Leguern,A., Meehan,S., Sablinski, T., Wee, S.,Powelson, J. “A Study of Tolerance in a Concordant Xenograft Model.”  Transplantation Proceedings, 1997; 29:923-4

  • Kimikawa, M., Sachs, D., Colvin, R., Bartholomew, A., Kawai, T., Cosimi, A.  “Modifications of  the Conditioning Regimen for Achieving Mixed Chimerism and Donor Specific Tolerance in Cynomolgus Monkeys.”  Transplantation, 1997; 64: 709-716

  • Benedetti, E., Coady, N., Asolati, M.,Dunn, T., Stormoen, B., Bartholomew, A., Vasquez, E., Pollak, R. “Peri-operative Treatment with Octreotide in Pancreas Transplantation: Results of a Prospective Randomized Clinical Trial.” Am J Surg., 1998; 175(1):14-7

  • Benedetti, E., Asolati, M.,Dunn, T., Walczak, D., Papp, P., Bartholomew, A., Smith, Y., Washington, A., Pollak, R. “Kidney Transplantation in Recipients with Mental Retardation: Clinical Results in a Single Center Experience.” Am J Kidney Dis., 1998; 31(3):509-12.

  • Hoffman, R., Rozler,E., Chute,J., Nelson, M., Chen, L.,Turian, J., Bartholomew, A., Brandt, J.  “Ex vivo Expansion of Human Hematopoietic Stem Cells: Implications for the Modern Blood Bank.” Vox Sang 1998; 74 Suppl 2:259-64

  • Ko DS, Bartholomew A, Poncelet AJ, Sachs DH, Huang C, LeGuern A, Abraham KI, Colvin RB, Boskovic S, Hong HZ, Wee SL, Winn HJ, Cosimi AB Demonstration of multilineage chimerism in a nonhuman primate concordant xenograft model. Xenotransplantation 1998; 5(4):298-304

  • Benedetti,E.,Dunn,T.,Massad,M.G.,Raofi,V.,Bartholomew,A.,Gruessner,R.W.G., Brecklin,C.,”Successful Living Related Simultaneous Pancreas-Kidney Transplant Between Identical Twins.” Transplantation. 1999; 67(6):915-918.

  • Brandt, J., Bartholomew, A., Nelson, M., Bruno, E., Moss, S.,Davis, T.,Chen, L., Fortman, J., Hoffman,R. “Ex Vivo Stem Cell Expansion Results in a Graft Capable of Hematologically Rescuing Lethally Irradiated Non-human Primates.” Blood. 1999; 94(1):106-13.

  • Medin, Jeffrey A., Brandt, John E., Rozler,Elen.,Nelson, Mary, Bartholomew, Amelia, Li,Congfen, Turian,Julius, Chute,John, Chung, Theodore, Hoffman, Ronald, “Ex vivo Expansion and Genetic Marking of Primitive Human and Baboon Hematopoietic Cells.” Ann N Y Acad Sci. 1999; 872:233-40; discussion 240-2.

  • Raofi V, Holman DM, Coady N, Vazquez E, Dunn TB, Bartholomew AM, Pollak R, Benedetti EA prospective randomized trial comparing the efficacy of tacrolimus versus cyclosporine in black recipients of primary cadaveric renal transplants. Am J Surg 1999; 177(4):299-302

  • Bartholomew, A.,  Cosimi, A. B., Sachs, D., Bailin, M., Boskovic, S., Colvin, R., Hong, H., Johnson, M., Kimikawa, M., LeGeurn, A., Meehan, S., Sablinski, T, Wee, S. L.,Powelson, J. “Tolerance in a Concordant Non-human Primate Model.”  Transplantation 1999; 68(11):1708-16

  • Halliday, L.C., Fortman, J.D., Nelson, M.C., Bartholomew, A., Hoffman,R., Bennett, B.T.,”A Modified Cage to Minimize Catheter Contamination in the Chronically Catheterized Baboon.” Contemporary Topics in Laboratory Animal Science. 1999; 38(4):16-19.

  • Kawai T, Poncelet A, Sachs DH, Mauiyyedi S, Boskovic S, Wee SL, Ko DS, Bartholomew A, Kimikawa M, Hong HZ, Abrahamian G, Colvin RB, Cosimi AB “Long-term Outcome and Alloantibody Production in a Non-Myeloablative Regimen for Induction of Renal Allograft Tolerance,” Transplantation. 1999; 68(11): 1767-75.

  • Gojo S, Bartholomew A, Xu Y, Neethling FA, Awwad M, Saidman S, Cosimi AB, Cooper DK Anti-Galalpha1-3Gal antibody levels in organ transplant recipients receiving immunosuppressive therapy Transplantation 2000; 69(5):914-7

  • VanBesien, K., Bartholomew, A., Stock, W., Peace, D., Devine, S., Scherr, D., Sosman, J., Chen, Y., Hoffman, R. “Fludarabine-based conditioning for allogeneic transplantation in adults with sickle cell disease.” Bone Marrow Transplant. 2000; 26(4):445-9

  • McIntosh, K., Bartholomew, A., “Stromal Cell Modulation of the Immune System.” Graft. 2000 3(6):324-328

  • Devine, S., Bartholomew, A., Hoffman, R. “Studies of Mesenchymal Stem Cell Transplantation in Non-Human Primates.” Graft. 2000 3(6):311-314

  • Devine, S., Bartholomew, A., Nelson, M., Mahmud, N.,Moran, S.,Hardy, W.,Sturgeon, C., Hewitt, T.,Chung, T.,Sher, D.,Weissmna, S., Deans, R., Moseley, A., Hoffman, R., “Homing and Engraftment of Culture Expanded Mesenchymal Stem Cells in a Non-Human Primate Model,” Exp Hematol. 2001 29(2):244-55

  • Bartholomew,A., Patil, S., Mackay, A., Nelson,M., Buyaner,D. , Hardy,W., Mosca,J., Sturgeon,C., Siatskas,M., Mahmud, N., Ferrer,K., Deans,R., Moseley,A., Hoffman,R. ,Devine,S. “Baboon mesenchymal Stem Cells Can Be Genetically Modified to Secrete Human Erythropoietin in Vivo,” Hum Gene Ther. 2001; 12(12):1527-41.  (cited >90 times)

  • Bartholomew, A., Sher, D., Sosler, S., Stock, W., Lazda, V.,Koshy, M., VanBesien, K. “Elimination of Allosensitization with Stem cell transplantation.” Transplantation. 2001 27;72(10):1653-5

  • Bartholomew, A, Sturgeon, C., Siatskas, M., Ferrer, K., McIntosh, K., Moran, S., Hardy, W., Devine, S., Deans, R., Moseley, A., Hoffman, R., “Mesenchymal Stem Cells Suppress Lymphocyte Proliferation In Vitro and Prolong Skin Graft Survival In Vivo,” Exp Hematol. 2002; 30(1): 1-7 (cited >500 times)

  • Devine,S., Cobbs, C., Jennings, M., Bartholomew,A., Hoffman,R., “Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into non-human primates,” Blood. 2003 Apr 15;101(8):2999-3001. Epub 2002 Dec 12.

  • Mahmud N, Pang W, Cobbs C, Alur P, Borneman J, Dodds R, Archambault M, Devine S, Turian J, Bartholomew A, Vanguri P, Mackay A, Young R, Hoffman R. “Studies of the route of administration and role of conditioning with radiation on unrelated allogeneic mismatched mesenchymal stem cell engraftment in a nonhuman primate model.,” Exp Hematol. 2004 May;32(5):494-501

  • Kaput J, Ordovas JM, Ferguson L, van Ommen B, Rodriguez RL, Allen L, Ames BN, Dawson K, German B, Krauss R, Malyj W, Archer MC, Barnes S, Bartholomew A, Birk R, van Bladeren P, Bradford KJ, Brown KH, Caetano R, Castle D, Chadwick R, Clarke S, Clement K, Cooney CA, Corella D, Manica da Cruz IB, Daniel H, Duster T, Ebbesson SO, Elliott R, Fairweather-Tait S, Felton J, Fenech M, Finley JW, Fogg-Johnson N, Gill-Garrison R, Gibney MJ, Gillies PJ, Gustafsson JA, Hartman Iv JL, He L, Hwang JK, Jais JP, Jang Y, Joost H, Junien C, Kanter M, Kibbe WA, Koletzko B, Korf BR, Kornman K, Krempin DW, Langin D, Lauren DR, Ho Lee J, Leveille GA, Lin SJ, Mathers J, Mayne M, McNabb W, Milner JA, Morgan P, Muller M, Nikolsky Y, van der Ouderaa F, Park T, Pensel N, Perez-Jimenez F, Poutanen K, Roberts M, Saris WH, Schuster G, Shelling AN, Simopoulos AP, Southon S, Tai ES, Towne B, Trayhurn P, Uauy R, Visek WJ, Warden C, Weiss R, Wiencke J, Winkler J, Wolff GL, Zhao-Wilson X, Zucker JD. The case for strategic international alliances to harness nutritional genomics for public and personal health.
    Br J Nutr. 2005 Nov;94(5):623-32.

  • Moadsiri A, Polchert D, Genrich K, Napoles P, Reina E, Turian J, Sith B, Bartholomew A.  “Mesenchymal Stem Cells Enhance Xenochimerism in NK Depleted Hosts,” Surgery. 2006 Aug;140(2):315-21.

  • Beggs, K, Lyubimov, A, Borneman, J, Bartholomew, A, Moseley, A, Dodds, R, Archambault, M, Smith, A, McIntosh, K. “Immunologic Consequences of Multiple, High-Dose Administration of Allogeneic Mesenchymal Stem Cells to Baboons” Cell Transplantation. 2006 15:711-721

  • Kaput J, Noble J, Hatipoglu B,Kohrs K, Dawson K, Bartholomew A. Application of nutrigenomic concepts to Type 2 diabetes mellitus. Nutr Metab Cardiovasc Dis. 2007 Feb;17(2):89-103.

  • Kaput J, Perlina A, Hatipoglu B, Bartholomew A, Nikolsky Y.Nutrigenomics: concepts and applications to pharmacogenomics and clinical medicine. Pharmacogenomics. 2007 Apr;8(4):369-90.

  • Sudan, D, Bacha, E, John, E, Bartholomew A “What’s New In Childhood Organ Transplantation,” Pediatrics In Review, 2007;28:439-453

  • LaStayo PC, McDonagh P, Napoles P, Bartholomew A, Lindstedt SL: Aging adults and high force resistance exercise: a descriptive report of whether an anabolic, muscle growth response can occur without a muscle damage or inflammatory response. J Geriatric Phys Ther. 2007; 30(3):128-34

  • Polchert, D, Sobinsky, J., Douglas, GW, Kidd, M, Moadsiri, A, Reina, E ., Genrich, K., Mehrota, S., Setty, S., Smith, B. and Bartholomew A. IFN-g Activation of Mesenchymal Stem Cells For Treatment and Prevention of Graft versus Host Disease. European Journal of Immunology 2008 Jun  (accompanied by editorial)

  • Bartholomew A, Polchert, D.,Szilagyi,E.,Douglas,GW, Kenyon, N. “Mesenchymal Stem Cells in the Induction of Transplantation Tolerance,” in press.

  • Bartholomew A, Siatskas,M, Sturgeon,C, Vidanovic,V, Zarev,P, Sosler,S,  Ferrer, K, Chong, A, Yin, D, Garcia, C, Hoffman, R, Devine, S.Peripheral Blood Stem Cell Grafts Mobilized By Recombinant Human Stem Cell Factor and Recombinant Granulocyte Colony-Stimulating Factor Suppress Host Anti-Donor Responses More Effectively Than Whole or Growth Factor Primed Bone Marrow Grafts,”  submitted

  • Ada Moadsiri, David Polchert, Phyllis Napoles, Christopher Garcia, John Karavitis, Andrew Maniotis, Amelia Bartholomew, “Factors Which Influence Mesenchymal Stem Cell Migration in Response to Tissue Injury,”submitted

  • Polchert, D, Maniotis, A, Moadsiri, A, Napoles,P, Turian,J, Ho, E.,Pundy,T, Yu,Z, Reina, E, Witte, P, Bartholomew A “Engineered Stem Cell Grafts Rescue Lethally Irradiated Hosts,” submitted

 




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