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Publications

  • Dr. Jose OberholzerJ. Oberholzer, T. Gross, U. Metzger: Traumatischer Chylothorax. Chir. Praxis 52, 19-29 (1997).

  • J. Oberholzer, J.M. Michel, S. Gueddi und Ph. Morel: Der Praxis-Fall: Vernichtende Bauchschmerzen ohne peritonitische Zeichen. Praxis (40), 1567-1569 (1997).

  • N. Cretin, L. Bühler, J. Oberholzer, B. Fournier, G. Mentha and Ph. Morel: Human islet allotransplantation - World experience and current status. Dig. Surg. 15, 656-662 (1998).

  • F. Triponez, J. Oberholzer, J. Lou, Ph. Morel : Transplantation of islets of Langerhans : Quo vadis ? Chirurgie ; 124, 5-12 (1999).

  • N. Cretin, L. Bühler, B. Fournier, A. Caulfield, J. Oberholzer, C. Becker, J. Philippe and Ph. Morel: Results of human islet allotransplantation in cystic fibrosis and type I diabetic patients. Transplant Proc 30, 315-316 (1998).

  • B. Fournier, E. Andereggen, L. Buhler, J. Oberholzer, R. Mage, C. Sinigaglia, G. Mentha, Ph. Morel: Long term evaluation of 9 islet autotransplantations after pancreatic resection. Schweiz. Med. Wochenschr. 128, 856-9 (1998).

  • K. Meyer, J.C. Irminger, L.G. Moss, L. Moitose de Vargas, J. Oberholzer, D. Bosco, Ph. Morel, Ph. Halban: Sorting human ß-cells by targeted expression of green fluorescent Protein (GFP). Diabetes 47, 1974-77 (1998).

  • J. Oberholzer, D. Yu, F. Triponez, N. Cretin, E. Andereggen, G. Mentha, D. White, L. Bühler, Ph. Morel and  J. Lou: Decomplementation with cobra venom factor prolongs survival of xenografted islets in a rat to mouse model. Immunology, 97, 173-180, (1999).

  • J. Oberholzer, F. Triponez, J. Lou, Ph. Morel: Clinical Islet Transplantation : a review. Ann N Y Acad Sci, 875, 189-99 (1999).

  • J. Lou, F. Triponez, J. Oberholzer, H. Wang, D. Yu, L. Bühler, N. Cretin, G. Mentha, C.B. Wollheim, Ph. Morel: Epression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells. Diabetes, 48, 1773-8  (1999).

  • J. Oberholzer , F. Triponez, R. Mage, E. Andereggen, L. Bühler, N. Crétin, B. Fournier, C. Goumaz, J. Lou, J. Philippe and Ph. Morel : Human islet transplantation: Lessons from 13 autologous and 13 allogeneic transplantations. Transplantation, 69, 1115-1123 (2000).

  • J. Oberholzer, F. Triponez, PY. Martin, C. Williamson, Ph. Morel : Daclizumab as escape therapy for late acute kidney rejection in the presence of FK506 nephrotoxicity. Transplant International, 13, 169-171 (2000).

  • T. Berney, T. Rüdisühli, J. Oberholzer, A. Caulfield, and Ph. Morel:
    Long-term metabolic results after pancreatic resection for severe chronic pancreatitis. Archives of Surgery, 135(9): 1106-11 (2000).

  • C. Toso, D. Brandhorst, J. Oberholzer, F. Triponez, L. Bühler, Ph. Morel: Isolation of adult porcine islets of Langerhans. Cell Transplant, 9(3): 297-305 (2000).

  • P. Salmon, J. Oberholzer, T. Occhiodoro, Ph. Morel, J. Lou, D. Trono :
    Reversible Immortalization of Human Primary Cells by Lentivector-Mediated Transfer of Specific Genes. Molecular Therapy, 2, 404-414, (2000).

  • A. Bonelo, D. Valmori, F. Triponez, J.M. Tiercy, G. Mentha, J. Oberholzer, P. Champagne, J.F. Romero, F. Esposito, I. Nebie, P. Romero, S. Herrera, G. Corradin, J.A. Lopez: Generation and characterization of malaria-specific human CD8(+) lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentation by liver cells. Eur J Immunol, 30, 3079-88, 2000.

  • F.Triponez, J.Oberholzer, Ph.Morel, C.Toso, D.Yu, N.Cretin, L.Buhler, P.Majno, G.Mentha, J. Lou: Xenogeneic islet re-transplantation in mice triggers an accelerated, species-specific rejection. Immunology, 101, 548-554, (2000).

  • P.Y. Benhamou, J. Oberholzer, C. Toso, L. Kessler, A. Penfornis, F. Bayle, C. Thivolet, X. Martin, N.Lefrançois, L. Badet, C. Colin, Ph. Morel : Human islet transplantation network for the treatment of type 1 diabetes: First (1999-2000) data from the swiss-french GRAGIL consortium. Diabetologia, 44, 859-864 (2001).

  • D.Pierucci, S. Cicconi, P.Bonini, F. Ferrelli, D.Pastore, C.Matteucci, L. Marselli, P. Marchetti, F. Ris, P. Halban, J. Oberholzer, M. Federici, F. Cozzolino, R. Lauro, P. Borboni and L. Marlier: NGF-Withdrawal Induces Apoptosis in Pancreatic -Cells in vitro. Diabetologia, 44:1281-95 (2001).

  • J. Oberholzer, C. Toso, F. Ris, P. Bucher, F. Triponez, A. Demirag, J. Lou and Ph. Morel: ß-cell replacement for the Treatment of Diabetes. Ann N Y Acad Sci, 944: 373-387 (2001).

  • T. Berney, A. Caulfield, J. Oberholzer, L. Buhler, C. Toso, Ph. Morel : Islet of Langerhans autotransplantation : Rationale, Results and New Developments. Graft, 4 : 535-543 (2001).

  • L. Buhler, T. Berney, A. Caulfield, J. Oberholzer, C. Toso, R. Alejandro, D. Cooper, C. Ricordi, Ph.Morel : Transplantation of islets of Langerhans: new developments. Swiss Med Wkly. 22 :131(47-48):671-80 (2001)

  • B. Ritz-Laser, J. Oberholzer, C. Toso, M.C. Brulhart, K. Zakrzewska, F. Ris, Ph. Morel, J. Philippe: Molecular detection of circulating ß-cells after islet transplantation. Diabetes, 51(3):557-61 (2002).

  • J.Oberholzer, C. Toso, F. Triponez, F. Ris, P. Bucher, A. Demirag, J. Lou, P. Majno, L. Buehler, J. Philippe and P. Morel : Human islet allotransplantation with basiliximab in type I diabetic patients with end-stage renal failure. Transpl Proc, 34(3):823-5, (2002).

  • C. Toso, J. Oberholzer, F. Ris, F. Triponez, P. Bucher, A. Demirag, E. Andereggen, L. Buehler, N. Cretin, B. Fournier, J. Lou, P. Majno, Y. Hong and Ph. Morel: Factors affecting human islet of Langerhans isolation yields. Transpl Proc, 34(3):826-7, (2002).

  • P. Majno, G. Mentha, P. Morel, C. Le Coultre, J. Oberholzer, C. Toso, B. Borisch, J. Fasel Left lobe splitting and full right-full left splitting: study of the portal anatomy on corrosion casts and on autopsy livers. Transpl Proc., 34(3):769-70, (2002).

  • F. Triponez, J. Oberholzer, C. Toso, P. Majno, P.-Y. Martin and Ph. Morel: Human islet re-transplantation in a patient with type I diabetes. Transplant International, 15 (4) : 200-2, (2002).

  • H. Yang, P. Majno, P. Morel, C. Toso, F. Triponez, J. Oberholzer, G. Mentha, J. Lou: Prostaglandin e(1) protects human liver sinusoidal endothelial cell from apoptosis induced by hypoxia reoxygenation. Microvasc Res  64(1):94-103, (2002).

  • K. Maedler, A. Fontana, F. Ris, P. Sergeev, C. Toso, J. Oberholzer, R. Lehmann, F. Bachmann, A. Tasinato, G. A. Spinas, P. A. Halban, and M. Y. Donath : FLIP switches Fas-mediated glucose signaling in human pancreatic ß-cells from apoptosis to cell replication. Proc Natl Acad Sci USA, 99 (12) : 8236-41, (2002).

  • F. Ris, E. Hammar, D. Bosco, C. Pilloud, J. Oberholzer, Ph. Morel, D. Rouiller and P.A. Halban: Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human ß-cells in vitro. Diabetologia, 45:841–850, (2002).

  • C. Toso, F. Ris, G. Mentha, J. Oberholzer, Ph. Morel and P. Majno : Potential impact of liver splitting on the number of available graft. Transplantation, 74(2):222-6, (2002).

  • T. H.Nguyen, J. Oberholzer, J. Birraux, P. Majno, Ph. Morel and D. Trono: Highly efficient lentiviral vector-mediated transduction of nondividing, fully re-implantable primary hepatocytes. Mol Ther, 6(2):199, (2002).

  • K. Maedler, P. Sergeev, F. Ris, J. Oberholzer, H. I. Joller-Jemelka, G. A. Spinas, N. Kaiser, P. A. Halban and M. Y. Donath: Glucose-induced b-cell production of interleukin-1b contributes to glucotoxicity in human pancreatic islets. Journal of Clinical Investigation, 110(6):851-860, (2002).

  • J. Oberholzer and Ph. Morel: Perspective in the treatment of diabetes by islet and pancreas transplantation. Diabetes and Metab, 28(4 Pt2): 27-32 (2002).

  • P. Majno, G. Mentha, P. Morel, A. Segalin, D. Azoulay, J. Oberholzer, C. Le Coultre, J. Fasel: Arantius' ligament approach to the left hepatic vein and to the common trunk. J Am Coll Surg, 195(5):737-9 (2002).

  • L. Kessler, R. Passemard, J. Oberholzer, P.Y. Benhamou, P. Bucher, C. Toso, P. Meyer, L. Meyer, F. Penfornis, L. Badet, P. Wolf, Ph. Morel and M. Pinget on behalf of the GRAGIL group: Reduction of Blood Glucose Variability in Type 1 Diabetic Patients Treated By Pancreatic Islet Transplantation: Interest of continuous glucose monitoring. Diabetes Care. 25(12):2256-2262 (2002).

  • A. Gamulin, J.Oberholzer (corresponding author), E. Bompas, L. Rubbia-Brandt, P. Majno, Ph. Morel, MD and G. Mentha: Use of Error : An unusual, presumably hepatic mass. Lancet, 360(9350):2066 (2002).
  • Oberholzer J, Shapiro AM, Lakey JR, Ryan EA, Rajotte RV, Korbutt GS, Morel P, Kneteman NM:  Current status of islet cell transplantation.  Adv Surg. 2003;37:253-82

  • K. Maedler, J. Oberholzer, P. Bucher, G. A. Spinas, and  Y. M. Donath. Monounsaturated Fatty Acids Prevent the Deleterious Effects of Palmitate and High Glucose on Human Pancreatic beta-Cell Turnover and Function. Diabetes, 52(3):726-33 (2003).

  • C. Toso, T. Berney, J. Oberholzer, J. Chave, PY. Martin, L. Buhler, E. Zeender, D. Bosco, Ph. Morel: Kidney-pancreas transplantation in a long term non-progressor HIV infected recipient. Am J Transplantation, 3(5):631-633 (2003).

  • C. Toso, J. Oberholzer (corresponding author), I. Ceausoglu, Ph. Morel, B. Rochat, F. Ris, A. Rehor, F. Triponez, P. Bucher, C. Wandrey, U. Schuldt, J. Belenger, J. Lou, P. Majno, D. Hunkeler : Intraportal injections of 400mm multicomponent microcapsules in a large animal model. Transplant International, 16(6):405-10 (2003).

  • J. Oberholzer, Z. Mathe, T. Berney, P. Bucher, L. Buhler, F. Triponez, D. Bosco, B. Fournier, P. Majno, J. Philippe and Ph. Morel : Islet autotransplantation after left pancreatectomy for non-enucleable insulinoma. Am J Transplantation. 3(10):1302-7 (2003).

  • C. Toso, Ph. Morel, P. Bucher, J. Shapiro, Z. Mathe, S. Demuylder, D. Bosco, T. Berney, J. Philippe and J. Oberholzer : Insulin-independence after conversion to tacrolimus and sirolimus-based immunosuppression in islet-kidney recipients. Transplantation, 15;76(7):1133-4 (2003).

  • E. Rafael, E.A. Ryan, B.W. Paty, J. Oberholzer, S. Imes, P. Senior, C. McDonald, J.R. Lakey, A.M. Shapiro. Changes in liver enzymes after clinical islet transplantation. Transplantation, 76(9):1280-4 (2003).

  • D. Hunkeler, R. Rajotte, D. Grey, P. Morel, G. Skjak-Break, G. Korbutt, R. Gill, J. Oberholzer: Bioartificial organ grafts: a view at the beginning of the third millennium. Artif Cells Blood Substit Immobil Biotechnol,  31(4):365-82 (2003).

  • J.G. Avila, T. Tsujimura, J. Oberholzer, T. Churchill, P. Salehi, AM James Shapiro, J.R.T. Lakey Intraductal glutamine administration improves pancreatic islet isolation outcomes. Cell Transplant, 12(8):877-81 (2003).

  • Oberholzer J. Treatment of insulin-dependent diabetes: new therapeutics. Cellular replacement: facts and perspectives. Bull Acad Natl Med. 2003;187(7):1297-306.

  • S. Sigrist, J. Oberholzer (corresponding author), A. Bohbot, G. Esposito, K. Mandes,  P. Lamartine, C. Toso, P. Bucher, T. Berney, A. Belcourt, M. Pinget, L. Kessler: Activation of human macrophages by allogeneic islet preparations: Inhibition by AOP-RANTES and heparinoids. Immunology, 111(4):416-21, 2004.

  • F. Ris, C. Toso, F. Unno Veith, P. Majno, Ph. Morel and J. Oberholzer (corresponding author): Are criteria for islet and pancreas donors sufficiently different to minimize competition? Am J Transplantation, 4(5):763-6, 2004.
  • A.Guignard, J. Oberholzer, P.Y. Benhamou, S. Touzet, P. Bucher, A. Penfornis, F. Bayle, L. Kessler, A. Thivolet, X.Martin, L. Badet, P. Morel,C. Colin. Cost-analysis of human islet transplantation for the treatment of type I diabetes in the Swiss-French consortium GRAGIL. Diabetes Care, 27(4):895-900, 2004.

  • Kessler L, Bucher P, Milliat-Guittard L, Benhamou PY, Berney T, Penfornis A, Badet L, Thivolet C, Bayle F, Oberholzer J, Renoult E, Brun MJ, Rifle G, Atlan C, Colin C, Morel P; GRAGIL Group. Influence of islet transportation on pancreatic islet allotransplantation in type 1 diabetic patients within the Swiss-French GRAGIL network. Transplantation. 2004 Apr 27;77(8):1301-4

  • Bucher P, Mathe Z, Bosco D, Oberholzer J, Toso C, Andres A, Buhler L, Morel P, Berney T. Microbial surveillance during human pancreatic islet isolation. Transplant Proc. 2004 May;36(4):1147-8.

  • Berney T, Mathe Z, Bucher P, Demuylder-Mischler S, Andres A, Bosco D, Oberholzer J, Majno P, Philippe J, Buhler L, Morel P. Islet autotransplantation for the prevention of surgical diabetes after extended pancreatectomy for the resection of benign tumors of the pancreas. Transplant Proc. 2004 May;36(4):1123-4.

  • Berney T, Bucher P, Mathe Z, Andres A, Bosco D, Mage R, Toso C, Oberholzer J, Becker C, Philippe J, Buhler L, Morel P. Islet of Langerhans allogeneic transplantation at the University of Geneva in the steroid free era in islet after kidney and simultaneous islet-kidney transplantations. Transplant Proc. 2004 May;36(4):1121-2.

  • Bucher P, Mathe Z, Bosco D, Becker C, Kessler L, Greget M, Benhamou PY, Andres A, Oberholzer J, Buhler L, Morel P, Berney T. Morbidity associated with intraportal islet transplantation. Transplant Proc. 2004 May;36(4):1119-20.

  • Mathe Z, Bucher P, Bosco D, Andres A, Fux C, Toso C, Oberholzer J, Wandrey C, Sainz-Vidal D, Espinosa D, Buhler L, Morel P, Berney T. Short-term immunosuppression reduces fibrotic cellular infiltration around barium-M-alginate microbeads injected intraportally. Transplant Proc. 2004 May;36(4):1199-200.

  • Tsujimura T, Kuroda Y, Avila JG, Kin T, Oberholzer J, Shapiro AM, Lakey JR.Influence of pancreas preservation on human islet isolation outcomes: impact of the two-layer method. Transplantation. 2004 Jul 15;78(1):96-100.

  • Dong G, Sankary HN, Malago M, Oberholzer J, Panaro F, Knight PS, Jarzembowski TM, Benedetti E, Testa G. Cadaver iliac vein outflow reconstruction in living donor right lobe liver transplantation. J Am Coll Surg. 2004 Sep;199(3):504-7

  • T. Jarzembowski, H. Sankary, D. Bogetti, A. Manzelli, E. Ong, J. Oberholzer, E. Benedetti and G. Testa: Living Donor Liver Graft Salvage After Rupture Of Hepatic Artery Pseudoaneurysm. Accepted for publication, International Surgery, 2004.

  • Kneteman NM, Oberholzer J, Al Saghier M, Meeberg GA, Blitz M, Ma MM, Wong WW, Gutfreund K, Mason AL, Jewell LD, Shapiro AM, Bain VG, Bigam DL  Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma. Liver Transpl. 2004 Oct;10(10):1301
  • J. Oberholzer, M. Alsaghier, N. Kneteman: Steroid-avoidance in Liver Transplantation. Canadian Journal of Gastroenterology. In press. 
  • Oberholzer J, Testa G, Sankary H, John E, Thielke J, Benedetti E. Kidney transplantation at the University of Illinois at Chicago from 1988-2004.  Clin Transpl. 2004;143-9

  • J. Oberholzer, J. Thielke, B. Hatipoglu, G. Testa, H. N. Sankary, E. Benedetti.  IMMEDIATE CONVERSION FROM TACROLIMUS TO CYCLOSPORINE IN THE TREATMENT OF POST-TRANSPLANT DIABETES MELLITUS. Transplant Proc, 2005 Mar;37(2):999-1000.
  • Andres A, Toso C, Morel P, Bosco D, Bucher P, Oberholzer J, Mathe Z, Mai G, Wekerle T, Berney T, Buhler LH: Macrophage depletion prolongs discordant but not concordant islet xenograft survival.  Transplantation. 2005 Mar 15; 79(5):543-9.
  • Bucher P, Oberholzer J, Bosco D, Mathe Z, Toso C, Buhler LH, Berney T, Morel P:  Microbial surveillance during human pancreatic islet isolation. Transpl Int. 2005 May; 18(5):584-9.
  • Toso C, Mathe Z, Morel P, Oberholzer J, Bosco D, Sainz-Vidal D, Hunkeler D, Buhler LH, Wandrey C, Berney T: Effect of microcapsule composition and short-term immunosuppression on intraportal biocompatibility.  Cell Transplant. 2005; 14(2-3):159-67.
  • Rondelli D, Abbasian J, Arpinati M, Panaro F, Porubsky M, Manzelli A, Oberholzer J, Benedetti E, Testa G: Different reconstitution of peripheral blood lymphocytes and dendritic cells in liver and kidney transplant patients. Transplant Proc. 2005 Jan-Feb;37(1):49-50 
  • Bogetti D, Jarzembowski TM, Sankary HN, Manzelli A, Knight PS, Chejfec G, Cotler S, Oberholzer J, Testa G, Benedetti EHepatic ischemia/reperfusion injury can be modulated with thymoglobulin induction therapy.  Transplant Proc. 2005 Jan-Feb;37(1):404-6
  • Andres A, Toso C, Morel P, Bosco D, Bucher P, Oberholzer J, Mathe Z, Mai G, Wekerle T, Berney T, Buhler LH:  Phylogenetic disparity influences the predominance of direct over indirect pathway of antigen presentation in islet xenotransplantation.  Transplant Proc. 2005 Jan-Feb;37(1):463-5.
  • Bucher P, Oberholzer J, Bosco D, Mathe Z, Toso C, Buhler LH, Berney T, Morel P: Microbial surveillance during human pancreatic islet isolation.  Transpl Int. 2005 May; 18(5):584-9.
  • Thielke J, DeChristopher PJ, Sankary H, Oberholzer J, Testa G, Benedetti E:  Highly successful living donor kidney transplantation after conversion to negative of a previously positive flow-cytometry cross-match by pretransplant plasmapheresis.  Transplant Proc. 2005 Mar; 37(2):643-4.
  • Walczak D, Calvert D, Oberholzer J, Testa G, Sankary H, Benedetti E: Effect of race on the occurrence of posttransplant diabetes in kidney transplant recipients treated with early steroid discontinuation.  Transplant Proc. 2005 Mar; 37(2):819-21.
  • Pham K, Kraft K, Thielke J, Oberholzer J, Sankary H, Testa G, Benedetti E:  Limited-dose Daclizumab versus Basiliximab: a comparison of cost and efficacy in preventing acute rejection.  Transplant Proc. 2005 Mar; 37(2):899-902.
  • Toso C, Mathe Z, Morel P, Oberholzer J, Bosco D, Sainz-Vidal D, Hunkeler D, Buhler LH, Wandrey C, Berney T: Effect of microcapsule composition and short-term immunosuppression on intraportal biocompatibility.  Cell Transplant. 2005; 14(2-3):159-67. 
  • Nguyen T, Mai G, Villiger P, Oberholzer J, Salmon P, Morel P, Bühler L, Trono D: Treatment of acetaminophen-induced acute liver failure in the mouse with conditionally immortalized human hepatocytes.. J of Hepatology, 2005 Sep 15.
  • Walczak DA, Calvert D, Jarzembowski TM, Testa G, Sankary HN, Thielke J, Oberholzer J, Benedetti E.  Increased risk of post-transplant diabetes mellitus despite early steroid discontinuation in Hispanic Kidney transplant recipients.  Clinical Transplantation  2005: 19: 527-531
  • J. Oberholzer, E. John, A. Lumpaopong, G. Testa, H. N. Sankary, L. Briars, K. A. Kraft, P. S. Knight, P. Verghese, E. Benedetti: Early discontinuation of steroids is safe and effective in pediatric kidney transplant recipients. Pediatric Transplantation, 2005 Aug;9(4):456-63.
  • Bogetti D, Sankary HN, Jarzembowski TM, Manzelli A, Knight PS, Thielke J, Chejfec G, Cotler S, Oberholzer J, Testa G, Benedetti E:  Thymoglobulin induction protects liver allografts from ischemia/reperfusion injury.  Clinical Transplantation 2005: 19: 507-511
  • Hatipoglu B, Benedetti E, Oberholzer J.: Islet transplantation: current status and future directions. Curr Diab Rep. 2005 Aug;5(4):311-6.

  • M. Marinov, S. Di Domenico, P.  Mastrodomenico, G Jacobsen, H Sankary, G. Testa, J. Oberholzer, M. Porubsky, E. Benedetti: Use of the splenic vessels for an ABO incompatible renal transplant in a patient with thrombosis of the vena cava. Am J Transplant. 2005 Sep;5(9):2336-7.

  • Villiger P, Ryan EA, Owen R, O'kelly K, Oberholzer J, Saif FA, Kin T, Wang H, Larsen I, Blitz SL, Menon V, Senior P, Bigam DL, Paty B, Kneteman NM, Lakey JR, Shapiro AM.  Prevention of bleeding after islet transplantation: lessons learned from a multivariate analysis of 132 cases at a single institution. Am J Transplant, 2005 Dec;5(12):2992-8.

  • J. Avila, B. Barbaro, A. Gangemi, T. Romagnoli, J. Kuechle, M. Hansen, J. Shapiro, G. Testa, H. Sankary,  E. Benedetti, J. Lakey and J. Oberholzer: Intraductal Glutamine Administration Reduces Oxidative Injury During Human Pancreatic Islet Isolation. Am J Transplant, 2005, 05 Dec;5(12):2830-7.
  • José G. Avila, Yong Wang, Barbara Barbaro, Antonio Gangemi,  Merigeng Qi,  Joseph Kuechle, Nicole Doubleday, Marc Doubleday, Thomas Churchill, Payam Salehi, James Shapiro,  Louis H. Philipson, Enrico Benedetti, Jonathan RT Lakey and José Oberholzer. Improved Outcomes in Islet Isolation and Transplantation by the Use of a Novel Hemoglobin-based O2 Carrier. American Journal of Transplantation, 2006; 6: 2861–2870.

  • Verónica Gorodner, Santiago Horgan, Carlos Galvani, Antonio Manzelli, José Oberholzer, Howard Sankary, Giuliano Testa,  Enrico Benedetti.  Routine left robotic assisted laparoscopic donor nephrectomy is as effective regardless of the presence of vascular anomalies.  Transplant International, 19 (2006) 636–640.
  • Rokstad AM, Donati I, Borgogna M, Oberholzer J, Strand BL, Espevik T, Skjak-Braek G Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate.  Biomaterials. 2006 Sep;27(27):4726-4737.
  • Gimi B, Leoni L, Oberholzer J, Braun M, Avila J, Wang Y, Desai T, Philipson LH, Magin RL, Roman BB. Functional MR microimaging of pancreatic beta-cell activation.
    Cell Transplant. 2006;15(2):195-203.

  • Eberhardt M, Salmon P, von Mach MA, Hengstler JG, Brulport M, Linscheid P, Seboek D, Oberholzer J, Barbero A, Martin I, Muller B, Trono D, Zulewski H. Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets.
    Biochem Biophys Res Commun. 2006 Jul 7;345(3):1167-76.
  • Testa G, Malago M, Porubsky M, Marinov M, Sankary H, Oberholzer J, Nadalin S, Benedetti E. Hilar early division of the hepatic duct in living donor right hepatectomy: The probe-and-clamp technique. Liver Transpl. 2006 Sep;12(9):1337-41.
  • Maedler K, Schumann DM, Schulthess F, Oberholzer J, Bosco D, Berney T, Donath MY. Aging Correlates With Decreased {beta}-Cell Proliferative Capacity and Enhanced Sensitivity to Apoptosis: A Potential Role for Fas and Pancreatic Duodenal Homeobox-1. Diabetes. 2006 Sep;55(9):2455-62.

  • Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, Donath MY. Low Concentration of Interleukin-1{beta} Induces FLICE-Inhibitory Protein-Mediated {beta}-Cell Proliferation in Human Pancreatic Islets. Diabetes. 2006 Oct;55(10):2713-22.
  • Salehi P, Hansen MA, Avila JG, Barbaro B, Gangemi A, Romagnoli T, Wang Y, Qi, M, Murdock P, Benedetti E, Oberholzer J. Human Islet Isolation Outcomes From Pancreata Preserved with Histidine-Tryptophan Ketoglutarate versus University of Wisconsin Solution. Transplantation. 2006 Oct 15;82(7):983-5.
  • Benedetti E, Holterman M, Asolati M, Di Domenico S, Oberholzer J, Sankary H, Abcarian H, Testa Living related segmental bowel transplantation: from experimental to standardized procedure.  Ann Surg. 2006 Nov;244(5):694-9.
  • Grim SA, Slover CM, Sankary H, Oberholzer J, Benedetti E, Clark NM. Risk factors for wound healing complications in sirolimus-treated renal transplant recipients. Transplant Proc. 2006 Dec;38(10):3520-3

  • Kaplan B, Gangemi A, Thielke J, Oberholzer J, Sankary H, Benedetti E. Successful rescue of refractory, severe antibody mediated rejection with splenectomy.  Transplantation. 2007 Jan 15;83(1):99-100. 
  • Asolati M, Testa G, Gangemi A, Sankary H, Oberholzer J, Benedetti E.  'Prope' tolerance in a noncompliant living related small bowel transplant recipient after severe rejection.  Transplantation. 2007 Jan 15;83(1):77-9. 
  • Horgan S, Galvani C, Gorodner M, Jacobsen G, Oberholzer J, Fisichella P, Moser F, Testa G, Sankary H, Bogetti D, Manzelli A, Benedetti E. Effect of Robotic Assistance on the “Learning Curve” for Laparoscopic Hand-Assisted Donor Nephrectomy (RHADN). Surg. Endosc. 2007 Feb 8.

  • Lumpaopong A, Mathew AV, John E, Jelnin V, Benedetti E, Testa G, Oberholzer J, Sankary H, Ruiz C. Early coronary calcification in children and young adults with end-stage renal disease. Transplant Proc. 2007 Jan-Feb;39(1):37-9.
  • Toso C, Meeberg GA, Bigam DL, Oberholzer J, Shapiro AM, Gutfreund K, Ma MM, Mason AL, Wong WW, Bain VG, Kneteman NM. De novo sirolimus-based immunosuppression after liver transplantation for hepatocellular carcinoma: long-term outcomes and side effects.  Transplantation. 2007 May 15;83(9):1162-8

  • West P, Schmiedeskamp M, Neeley H, Oberholzer J, Benedetti E, Kaplan B. Use of high-dose ganciclovir for a resistant cytomegalovirus infection due to UL97 mutation. Transpl Infect Dis. 2007 Jul 1

  • Grim SA, Pham T, Thielke J, Sankary H, Oberholzer J, Benedetti E, Clark NM.  Infectious complications associated with the use of rituximab for ABO-incompatible and positive cross-match renal transplant recipients. Clin Transplant. 2007 Sep-Oct;21(5):628-32.

  • Horgan S, Galvani C, Gorodner V, Bareato U, Panaro F, Oberholzer J, Benedetti E. Robotic distal pancreatectomy and nephrectomy for living donor pancreas-kidney transplantation. Transplantation. 2007 Oct 15;84(7):934-6.

  • Barbaro B, Salehi P, Wang Y, Qi M, Gangemi A, Kuechle J, Hansen MA, Romagnoli T, Avila J, Benedetti E, Mage R, Oberholzer J. Improved Human Pancreatic Islet Purification With the Refined UIC-UB Density Gradient. Transplantation. 2007 Nov 15;84(9):1200-3.

  • Shu L, Sauter NS, Schulthess FT, Matveyenko AV, Oberholzer J, Maedler K. TCF7L2 regulates -cell survival and function in human pancreatic islets. Diabetes. 2007 Dec 10
  • Meirigeng Qi, Berit Lokensgard Strand, Yrr Morch, Igor Lacik. Yong Wang, Payam Salehi, Barbara Barbaro, Antonio Gangemi, Joseph Kuechle, Travis Romagnoli, Michael A.Hansen, Lisette A.Rodriguez, Enrico Benedetti, David Hunkeler, Gudmund Skjak-Braek and Jose Oberholzer. "Encapsulation of human islets in novel inhomogeneous alginate-Ca2+/Ba2+ microbeads: in vitro and in vivo function" Artif Cells Blood Substit Immobil Biotechnol. 2008;36(5):403-20.
  • B. Kaplan, P. West, H. Neely, J. Martellotto, R. Iqbal, A. Gangemi, B. Hatipoglu, E. Benedetti and J. Oberholzer.”Use of Low dose tacrolimus, mycophenolate mofetil and maintenance IL-2 receptor blockade in an islet transplant recipient. Clinical Transplantation 2008: 22:250-253
  • A. Gangemi, P. Salehi, B. Hatipoglu, J. Martellotto, B. Barbaro, J.B. Kuechle, M. Qi, Y. Wang, P. Pallan, C. Owens, J. Bui, D. West, B. Kaplan, E. Benedetti and J. Oberholzer. Islet Transplantation for Brittle Type 1 Diabetes: The UIC Protocol.  American Journal of Transplantation 2008; 8: 1- 12
  • Beier UH, Kaplan B, Setty S, Samuel S, Mathew AV, Oberholzer J, Benedetti E, John E.  Electrolyte imbalances in pediatric living related small bowel transplantation.  Transplantation. 2008 Jan 27;85(2):217-23.
  • West-Thielke P, Herren H, Thielke J, Oberholzer J, Sankary H, Raofi V, Benedetti E, Kaplan B. Results of positive cross-match transplantation in African American renal transplant recipients. Am J Transplant. 2008 Feb;8(2):348-54
  • Raofi V, Beatty E, Testa G, Abcarian H, Oberholzer J, Sankary H, Grevious M, Benedetti E. Combined living-related segmental liver and bowel transplantation for megacystis-microcolon-intestinal hypoperistalsis syndrome. J Pediatr Surg. 2008 Feb;43(2):e9-e11.
  • Salehi P, Stull MA, Martellotto J, Gangemi A, Hatipoglu B, Benedetti E, Oberholzer J. Case report: diabetic myonecrosis of the neck complicated by infection in an islet transplanted patient. J Diabetes Complications. 2008 Mar 20
  • Barbaro B, Kuechle J, Salehi P, Rodriguez L, Qi M, Gangemi A, Benedetti E, Oberholzer J. Increased albumin concentration reduces apoptosis and improves functionality of human islets.  Artif Cells Blood Substit Immobil Biotechnol. 2008;36(1):74-81
  • Mehrabian M, Schulthess FT, Nebohacova M, Castellani LW, Zhou Z, Hartiala J, Oberholzer J, Lusis AJ, Maedler K, Allayee H. Identification of ALOX5 as a gene regulating adiposity and pancreatic function. Diabetologia. 2008 Jun; 51(6):978-88.
  • Maya Campara, James Thielke, Thuy Ommert, Patricia West-Thielke, Jose Oberholzer, Enrico Benedetti and Bruce Kaplan: ABO Incompatible Renal Transplantation in an HIV- Seropositive Patient.  Transplantation: volume 86, number1, July 15, 2008
  • Pier Cristoforo Giulianotti, M.D.; Joseph Kuechle; Payam Salehi, M.D., Ph.D.; Veronica
    Gorodner; Carlos Galvani, M.D.; Enrico Benedetti, M.D.; Jose Oberholzer, M.D..  "Robotic-Assisted Laparoscopic Distal Pancreatectomy of a Redo Case Combined with Autologous Islet Transplantation for Chronic Pancreatitis," Pancreas Journal.(in press January 2009).
  • Kaplan B, West-Thielke P, Herren H, Gill J, Knoll GA, Oberholzer J, Sankary H, Benedetti E. Reported isolated pancreas rejection is associated with poor kidney outcomes in recipients of a simultaneous pancreas kidney transplant. Transplantation. 2008 Nov 15;86(9):1229-33.
  • Marzban L, Tomas A, Becker TC, Rosenberg L, Oberholzer J, Fraser PE, Halban PA, Verchere CB. Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture. Diabetes. 2008 Nov;57(11):3045-55. Epub 2008 Aug 11
  • Kuechle JB, Pasha S, Sadat K, Tran J, Hatipoglu B, Bui JT, Chejfec G, Oberholzer J.  Pulmonary Sequestration With CCAM Type II Appearing as Adrenal Tumor Protruding Through a Bochdalek Hernia.  Int J Surg Pathol. 2008 Aug 12.
  • Ricordi C, Hering BJ, Shapiro AM; Clinical Islet Transplantation Consortium.Markmann J, Larsen CP, Kaufman D, Stock P, Korsgren O, Oberholzer J, Naji A, Hering BJ.  Beta-cell transplantation for diabetes therapy. Lancet. 2008 Jul 5;372(9632):27-8; author reply 29-30.
  • Grevious MA, Iqbal R, Raofi V, Beatty E, Oberholzer J, Cohen M, Abcarian H, Testa G, Benedetti E.  Staged approach for abdominal wound closure following combined liver and intestinal transplantation from living donors in pediatric patients.  Pediatr Transplant. 2008 Jun 4.
  • Campara M, West-Thielke P, Thielke J, Ommert T, Oberholzer J, Benedetti E, Kaplan B. ABO incompatible renal transplantation in an HIV-seropositive patient.  Transplantation. 2008 Jul 15;86(1):176-8
  • Qi M, Strand BL, Mørch Y, Lacík I, Wang Y, Salehi P, Barbaro B, Gangemi A, Kuechle J, Romagnoli T, Hansen MA, Rodriguez LA, Benedetti E, Hunkeler D, Skjåk-Braek G, Oberholzer J.  Encapsulation of human islets in novel inhomogeneous alginate-ca2+/ba2+ microbeads: in vitro and in vivo function.  Artif Cells Blood Substit Immobil Biotechnol. 2008;36(5):403-20
  • Giulianotti PC, Kuechle J, Salehi P, Gorodner V, Galvani C, Benedetti E, Oberholzer J.  Robotic-assisted laparoscopic distal pancreatectomy of a redo case combined with autologous islet transplantation for chronic pancreatitis.  Pancreas. 2009 Jan; 38(1):105-7.
  • Thielke JJ, West-Thielke PM, Herren HL, Bareato U, Ommert T, Vidanovic V, Campbell-Lee SA, Tzvetanov IG, Sankary HN, Kaplan B, Benedetti E, Oberholzer J.  Living donor kidney transplantation across positive crossmatch: the University of Illinois at Chicago experience.  Transplantation. 2009 Jan 27;87(2):268-73
  • Schulthess FT, Paroni F, Sauter NS, Shu L, Ribaux P, Haataja L, Strieter RM, Oberholzer J, King CC, Maedler K.  CXCL10 Impairs beta Cell Function and Viability in Diabetes through TLR4 Signaling.  Cell Metab. 2009 Feb; 9(2):125-39.

 

Other journals

  1. N. Cretin, L. Bühler, B. Fournier, A. Caulfield, J. Oberholzer, C. Becker, J. Philippe et Ph. Morel: Allotransplantation d‘îlots de Langerhans chez l‘humain. Méd et Hyg 55, 1284-6 (1997). 

  2. J. Oberholzer, F. Triponez, A. Caulfield, N. Cretin, B. Fournier, E. Andereggen, J. Lou, L. Bühler et J. Philippe, Ph. Morel: Transplantation d’îlots de Langerhans: Quo vadis? Med. et Hyg. (56), 1337-41 (1998).

  3. F. Triponez, J.M. Mégavand, J. Oberholzer, K. Francis, K. Djeballi, Ph. Morel et O. Huber : Résultats de la Chirurgie Laparoscopique du Reflux Gastro-Oesophagien. Med. et Hyg. (57), 1310-3 (1999).

  4. C. Toso, J. Oberholzer, F. Ris, F. Triponez, C. Becker, J. Philippe, Ph. Morel : Le traitement du diabète par transplantation : quelles sont les indications ? Méd et Hyg 58, 2218-22 (2000)

  5. J. Oberholzer, C. Toso, P.Y. Benhamou, C. Becker, P.Y. Martin, J. Philippe, Ph. Morel : Die Inselzelltransplantation zur Behandlung des Typ I Diabetes : Neue klinische Studie am Genfer Universitätspital. Schweizerische Aerztezeitung, 8, 395-400, 2001

 

Books and Book-chapter

  • Guide to Safety and Quality Assurance for Organs, Tissue and Cells. Council of Europe Publishing, 1st Edition, June 2002. ISNB 92-871-4891-0.

  • J. Oberholzer, AMJ Shapiro, JRT Lakey, E. A. Ryan, R. V. Rajotte, G. S. Korbutt, Ph. Morel and N. M Kneteman: Current Status of Islet Cell Transplantation. In J. L.Cameron’s Textbook of Advances in Surgery. Elsevier Science. 37: 253-82, 2003.

  • Guide to Safety and Quality Assurance for Organs, Tissue and Cells. Council of Europe Publishing, 2nd Edition, September 2004. ISNB 92-871-5518-6.

  • J. Oberholzer, G. Testa, H. Sankary, E. John, J. Thielke, E. Benedetti: Kidney Transplantation at the University of Illinois at Chicago from 1988 to 2004. In J. M. Cecka and P. I. Terasaki, Clinical Transplants 2005 (UCLA 2004) 143-149. Published by: UCLA Immunogenetics Center, Los Angeles, CA 90095

  • J. Oberholzer, J. Avila, E. Benedetti: “Standard (Open) Distal Pancreatectomy for Living Pancreas Donation”, Chapter 19, Pancreas Transplantation: The Donor in  Gruessner / Living Donor Organ Transplantation, McGraw-Hill Medical, 2007.

 

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