Patient's G.I. tract should be barium free.
(Optional) Administer cimetidine prior to injecting the radiopharmaceutical:
Give 300 mg intravenously 30 minutes prior to the study. (Dilute to 20 mL and infuse over 5 minutes. or
Give 300 mg orally 60 minutes prior to the study.
Tc-99m-pertechnetate as sodium pertechnetate is given by standard intravenous injection. An adult dose of 5 mCi is administered. The critical organ is the thyroid (0.12-0.2 rad/mCi).
30 minutes to 1 hour.
The radiopharmaceutical is actively secreted by gastric mucosa. Although all Meckel's diverticula do not contain functioning gastric mucosa, most that bleed do. Patient's with active hemorrhage can also be studied with tagged red blood cells (see Gastrointestinal Bleeding Study). While only 20% of Meckel's Diverticula contain ectopic mucosa, greater than 90% of diverticula that bleed do.