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PDF is a format for output and review, not a source format
intended for editing. Thus you can only do minor changes in
it, such as:
- re-typing some text with the text-touchup tool
- move text or graphics — but only on a per-line basis!
- change font face, size, color for (part of) a line of
text
- delete graphics with the object select tool
- insert a new line of text: Ctrl-click with the text-touchup
tool
For all major editing, you should go back to the original
source document and afterwards re-create the PDF output.
   
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