Analysis of Signal-to-Noise Ratio for RF Scroll Microcoils, B.Gimi, S.C.Grant, R.L Magin and G.Friedman, ENC 2000, 4/9/2000

In the investigation of mass-limited samples by high resolution NMR spectroscopy, the principal concern has been the optimization of the radio frequency (RF) transceiver coil to improve the signal-to-noise ratio (SNR) for the sample volume under investigation [1,2]. This challenge has been met successfully through the application of solenoidal wire microcoils, having dimensions of less than 2 mm, that are tailored to samples of less than 1 microliter. Another microcoil configuration, known as the scroll coil, also has been investigated recently [3,4]. The scroll coil, consisting of a single ribbon bilayer of conductor and insulator wound upon itself, takes advantage of the high sensitivity of a cylindrical geometry while incorporating additional sensing layers. Furthermore, this configuration offers more flexibility and accuracy in coil design, especially with the incorporation of microfabrication techniques, for RF coils of greatly reduced diameters (< 50 microns)..

Giorgio A. Moresi, Richard L. Magin, Brian Roman, "MicroCatheter Coils for In Vivo 31P NMRS: Applications to Genetic Models." International Society of Magnetic Resonance in Medicine, Tenth Scientific Meeting, Honolulu, Hawaii (in review).

Richard L. Magin, Samuel C. Grant, Giorgio Moresi, Brian Roman, Barjor Gimi, "Microcoil NMR: Theory and Applications." Talk at Biomedical Engineering Society Annual Meeting. Artificial Cells and Nanotechnology Track. October 2001.