Thursday, June 26

07.00

Breakfast

08.00 

EOSINOPHIL DEVELOPMENT, SURVIVAL AND DEATH
Session Chairs – Steven Ackerman and Leo Koenderman

08.00-08.10

Welcome and Introduction on Behalf of the Organizers
Steven Ackerman, Redwan Moqbel and Judah Denburg

08.10- 08.30

Steven Ackerman (University of Illinois, Chicago, IL, USA)
“Transcriptional regulation of the eosinophil developmental pathway: Eosinophilopoiesis 101 – a short course”

08.30-08.50

Atsushi Iwama (University of Tokyo, Tokyo, Japan)
“Role of GATA family transcription factors in eosinophil development”

08.50-09.10   

Paul Coffer (University Medical Center, Utrecht, The Netherlands)
"Divide, differentiate or die? Molecular mechanisms regulating the fate of eosinophil progenitors"

09.10-09.30

Stephane Esnault (University of Wisconsin, Madison, WI, USA)
“GM-CSF gene regulation/expression and autocrine survival functions in eosinophils”

09.30-09.50 

Kim Hamann (University of Chicago, Chicago, IL, USA)
“Cytokine, cellular and molecular mechanisms regulating eosinophil apoptosis”

09.50-10.10

Hans Uwe Simon (University of Bern, Bern, Switzerland)
“New pathogenic and therapeutic insights into eosinophilic diseases”

10.10

Refreshments and Open Poster Viewing

10.40

EOSINOPHIL PRIMING AND ACTIVATION I: RECEPTOR SIGNALING, INTEGRINS AND ADHESION
Session Chairs – Peter Weller and Paul Bertics

10.40-11.00

Leo Koenderman (University Medical Center, Utrecht, The Netherlands)
“Inside-out control of eosinophil integrins in vitro and in vivo”

11.00-11.20   

Nives Zimmermann (Children’s Hospital Medical Center (Cincinnati, OH, USA)
“Regulation of CCR3 expression and function on eosinophils”

11.20-11.40   

Rafeul Alam (National Jewish Medical and Research Center, Denver, CO, USA)
“IL-5 signal transduction pathways regulating eosinophil development/function”

11.40-12.00 

Paul Bertics (University of Wisconsin, Madison, WI, USA)
“Mechanisms and crosstalk of interleukin-5 signaling processes associated with eosinophil priming and activation”

12:00-12:.20

William Busse (University of Wisconsin, Madison, WI, USA)
“Effects of asthma treatment on airway eosinophils”

12.30-16.00 

Unscheduled Time for the 3Rs – Rest, Relaxation, Recreation

16:00 

EOSINOPHIL PRIMING AND ACTIVATION II: MECHANISMS OF MEDIATOR SECRETION IN INNATE VERSUS ADAPTIVE IMMUNE RESPONSES
Session Chairs – Redwan Moqbel and Marc Rothenberg

16.00-16.20 

K. Ravi Acharya - (University of Bath, Bath, UK)
“Structure-function relationships of eosinophil granule proteins”

16.20-16.40

Redwan Moqbel (University of Edmonton, Alberta, Canada)
“Regulatory pathways and mechanisms of eosinophil degranulation/secretion”

16.40-17.00

Christianne Bandeira-Melo (Fundação Oswaldo Cruz, Rio de Janeiro, Brasil)
“The role of leukocyte immunoglobulin-like receptors (LIRs) in eosinophil function:  Activation of human eosinophils through LIR-7”

17.00-17.20

Peter Weller (Beth Israel Deaconess Medical Center, Boston, MA, USA)
"Intracrine eicosanoid regulation of eosinophil secretion"

17.20-18.20 

Poster Viewing of Submitted Abstracts - Session I
(presenting authors of EVEN numbered posters available for discussion)

18.20 

Dinner and Free Concert on the Mountain (Snowmass Mountain)

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