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Bioengineering Technology Services

The UIC Department of Bioengineering has developed unique resources in this exciting and growing area. The faculty and staff are at the forefront of the biomedical field, and our close affiliation with the University of Illinois Medical Center at Chicago enables us to offer quality support to address your most challenging projects. This department currently partners with many major biomedical manufacturers (Abbott, Baxter, Biomet, General Electric and Siemens, for example) in the Chicago and northwest Indiana areas. This service offers you the unique opportunity to work on projects by using UIC resources as an extension of your development activities in a very cost-effective way.

The bioengineering department has the capability and resources to provide industry support in the following interdisciplinary areas:


Cell and Tissue Engineering

We have developed several systems for studying the effects of mechanical forces at the cellular level.  We have systems to expose cells to transitional fluid shear stress, laminar fluid shear stress, vibration and ultrasound.  These systems are compatible with one another so that they can be combined to expose cells to more than one stimulus.

The Laboratory for Biomolecular Imaging has several imaging and testing systems uniquely integrated to probe and determine molecular, cellular and physiological responses from nanometer-scale to millimeter-scale.  Multiple biological and physiological tasks can be accomplished, including toxicity tests, controlled drug release, real-time 3D tumor cell invasion, and tissue functionality.  The multiphoton microscope, one of a few available in the Chicago area, offers nonlinear optical techniques to scan and image in 3D.  In addition, our mechanical probes (laser optical tweezers and atomic force microscope) are ideal to elucidate how cells and tissues physically interact with and are controlled by nano- and micro-scale topological features of an extracellular environment.

Faculty experts:

Michael Cho, PhD, Associate Professor
Susan McCormick, PhD, Assistant Professor

Cellular Labs & Special Equipment

  • Cellular Transitional Flow Shear Stress System
  • Cellular Transitional Cylindrical Flow System
  • Cellular Vibration Exposure System
  • Cellular Ultrasound Treatment System

Biomolecular Imaging Special Equipment

  • Multiphoton microscope
  • Confocal microscope
  • Nanovid microscope
  • Laser optical tweezers
  • Atomic force microscope

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Chemical, Biomolecular and Nanobioengineering

Our faculty excel in nano, micro and batch processing using nanoparticles, viral, bacterial and eukaryotic cells that produce and process new and raw materials for product recovery, development of pharmaceuticals, nano-drug delivery and environmental protection. They also use applications of principles of nanotechnology in developing bioengineering processes, systems and products.

These include:

  • Biological nanoparticles design and manufacturing
  • Drug design, targeting and delivery
  • Gene delivery and therapy
  • Cancer diagnosis, prevention and treatment research and development through nanotechnology

Faculty experts:

Andreas Linninger, PhD, Associate Professor
G. Ali Mansoori, PhD, Professor
Christos Takoudis, PhD, Professor

Labs & Special Equipment

Equipment

  • Gel permeation, HPLC, GC chromatography (WATERS) - Columns need to be acquired by user 
  • Atomic Force Microscopes  (tips need to be acquired by user)
  • Supercritical fluids screening unit  (up to 15,000 psia and 100 Oc)
  • Ebuliometer
  • pH Meter
  • Microelectrophoresis – Zetha Meter
  • Viscometers
  • Potentiometers
  • Nano/Micro Laser Particle Counter
  • Calorimeters
  • Interfacial Tensiometers
  • Microscope

Software

  • Supercritical fluid/liquid solubility prediction
  • Heavy organics deposition from petroleum fluids
  • Phase equilibrium prediction of multicomponent mixtures: ionic and liquid metals solutions, colloidal solutions, petroleum fluids, polymer solutions and miscibility.

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Neural Engineering

The Laboratory of Neurotronic Communication specializes in information transfer between living neural systems and electronics, for monitoring or inducing neural activity, especially in the vision and olfaction sensory systems. We use traditional and novel electrophysiological techniques to evaluate animal models of disease, investigate novel therapeutic approaches, and exploit properties of living systems for sensor applications. We have expertise with in vivo and in vitro stimulation / recording protocols.

Faculty experts:

John Hetling, PhD, Associate Professor

Labs & Special Equipment

  • Electrophysiology of the eye (electroretinography, single-cell recording)
  • Ocular surgery, intraocular injection for pharmacology studies
  • Electrical stimulation of the retina / ocular tissues in vivo
  • Multielectrode array for cell culture / tissue recording and stimulation in vitro
  • Instrumentation development (analog electronics, microfabrication)
  • Finite element modeling of bioelectric tissue and hybrid neural systems
  • Culture of olfactory receptor neurons
  • Fluorescence microscopy

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CONTACT INFORMATION

Kenneth Brezinsky
UIC Engineering Corporate Relations 
Office 851 S. Morgan St. Rm 812
Chicago, IL 60607-7043 
Telephone: 312-996-5843 
Email: kenbrez@uic.edu