This volume of the AIDS Clinical Review is the eighth to be published since 1989, "focusing on specific areas in which important new advances have occurred in the diagnosis, therapy, and prevention of HIV infection and HIV-associated complications." Each of the reviews is written by the researcher who is directly involved in the research that is being reported. The first review provides the latest information concerning behavioral interventions to prevent HIV transmission, while the second review presents the current status of HIV vaccine development. Review three outlines what is known about the mechanism of mother-child vertical HIV transmission and number four assesses the risk of occupational HIV infection to health care workers. Review five presents an optimistic picture of the potential for preserving HIV-specific immunity when antiretroviral therapy is initiated early in the course of acute HIV infection.
The sixth review reports on the effect of new potent antiretroviral drug regimens, while the next two reviews deal specifically with the newly emerging antiretroviral regimens for treating HIV infection. The ninth review explains the current state of knowledge regarding cytokine and other immune-based therapies for HIV disease and the last review delves into an exploration of the problem of hepatitis B and C coinfection with HIV. These are excellent reviews that continue to add to the growing mass of clinical research data that is being created by the physicians, nurses, microbiologists, therapists, pharmacists, and epidemiologists who deal directly with patients suffering from HIV disease. This is a highly recommended book for all health science libraries and other research facilities.
1077. Out Here By Ourselves: The Stories of Young People Whose Mothers Have AIDS, by Diane Duggan. 2000. Garland Publishing/Taylor & Francis, 19 Union Square West, New York, NY 10003. 179p., bibliog., index. (Children of Poverty). ISBN 0-8153-3621-7. $50.00. (Descriptors: Children of AIDS Patients; Interviews Family Relationships; Mothers)
At the beginning of the AIDS epidemic in the U.S., the gay male was the most devastated group to be infected with the HIV virus. By 1997, women accounted for 20% of new AIDS cases, compared to 6% in 1982. More significantly, however, is that deaths from AIDS in 1996 decreased by 15% for men and increased by 3% for women. Many of these women are single mothers who sometimes transmit the infection to their unborn babies. Fortunately the majority of children of women with AIDS are not infected by HIV. They are, however, are profoundly affected by the illness and in many cases the death of their mothers.
This book reports on a study of "the impact of a mother's illness or death from AIDS on their adolescent and young adult children." The study wanted answers to two research questions: "What is the experience of adolescents and young adults who have a family member with AIDS?" and "What impact does this experience have on their feelings about themselves and on their behavior?" The first three chapters provide information on the purpose of the study, background for the study, and how the study was conducted. The young people's stories are presented in the fourth chapter and the fifth chapter discusses some of the common themes, such as "We're Out Here by Ourselves," "My Mother Had a Problem," "Me and My Mother Didn't Get Along," and "Something to Live for." The last chapter is a discussion of the results with implications.
This is a well-written book based on the author's dissertation. Little has been written on this topic, so this should encourage others to investigate more on the impact of AIDS on this group of children. However, it should be noted, that it was discovered that many of the children did not want to talk about this topic and did not want to participate in any type of healing process such as creating an AIDS quilt panel. This is a recommended book for all academic libraries.
1078. Teen Moms: The Pain and the Promise, by Evenly Legman, illustrated by Jam Motet. 1998. Morning Glory Press, 6595 San Harold Way, Bounce Park, CA 90620-3748. 190p., illus., bibliog., index. ISBN 1-88535. $14.95. (Descriptors: Sex Education; Teens)
Sex education never becomes dated, so this 1998 book has much to provide to the interested reader. Although, the book is not about sex education itself, it does discuss all of the after effects of a teen becoming pregnant. "The book effectively illustrates the harsh realities so many teenage mothers face." More than 500,000 teen women give birth each year, a frightening figure and one that we cannot ignore. Teen pregnancy prevention cannot just be focused on the female, it has to focus on both the male and female teen as well as the parents. This book is about the teen mothers and how having a baby has changed their lives forever, some for the good and others for the worse. Legman discusses such topics as "Why have sex so early," "Teen moms' feelings about men," "The meaning of motherhood," "Feelings about welfare and independence," and "Changed Lives--the pain and the promise." This is a well-written book that should be in all school and public libraries.
1079. Male Lust: Pleasure, Power, and Transformation, edited by Cheering Key, Jill Angle, Barouche Gold. 2000. Haworth Press, 10 Alice St., Binghamton, NY 13904-1580. 363p., bibliog., index. ISBN 1-56023-981-6, 1-56023-982-4 pbk. $49.95, $24.95 pbk. (Descriptors: Sexual Behavior of Men; Sexual Deviation)
Although not an AIDS-specific book, this is a very interesting book that discusses how sex and power mean so much to men: "the portrayal of sex as a competitive game, a matter of scoring and bases; the image of sex as an intrinsically desirable commodity, a reward offered to those who achieve, or who at least buy the right car; the valorization of the always-hard, always-ready dick." The stories that are contained in this collection represent a wide array of male experiences with sex and desire. These are personal essays and poems covering such topics as sexual abuse, S & M, pornography, and racism. Five of the essays are written by women and two by transgendered men. "This book reflects both gay and straight viewpoints and offers a positive sexual vision that moves far beyond the narrow messages offered in mainstream media." It is a recommended book for all academic libraries and most public library. The language that is used in some of the essays, however, may prevent some libraries from purchasing the book.
1080. Protease Inhibitors in AIDS Therapy, edited by Richard C. Ogden, Charles W. Flexner. 2001. Marcel Dekker, 270 Madison Ave., New York, NY 10016. 310p., illus., bibliog., index. (Infectious Disease and Therapy, no. 25) ISBN 0-8247-0461-4. $125.00. (Descriptors: Protease Inhibitors; Therapy)
Antiretroviral therapy began with zidovudine (AZT), followed by aspartyl protease, and now protease inhibitors. There have been many advances in the research and use of protease inhibitors, the most dramatic being the decrease in the number of deaths from opportunistic infections. When first introduced, the protease inhibitors were intended to be the forerunner of a cure, but that has not happened. "This book provides a timely and comprehensive look at the class of HIV protease inhibitors from a scientific and clinical perspective."
The 13 chapters and postscript cover: "HIV-1 Protease as a Target for AIDS Therapy," "Discovery and Early Development of Saquinavir," "Discovery and Early Development of Ritonavir and ABT-378," "Discovery and Early Development of Indinavir," "Discovery and Development of Nelfinavir (Viracept)," "Design and Synthesis of Amprenavir, A Novel HIV Protease Inhibitor," "HIV Protease Inhibitors in Early Development," "Pharmacology and Drug Interactions of HIV Protease Inhibitors," "Beneficial Pharmacokinetic Interactions: Are Two Protease Inhibitors Better Than One," "Protease Inhibitors: Clinical Efficacy," "Toxicities and Adverse Effects of Protease Inhibitors," "Resistance to HIV-1 Protease Inhibitors," "Expedited Drug Approval and HIV Protease Inhibitors," and "Use of Protease Inhibitors in the Management of HIV/AIDS."
This is an excellent book that provides a history of protease inhibitors for the researcher. It is not a book for the layperson. "Many issues make HIV/AIDS a singular medical syndrome, in both the developed and developing worlds. The drugs described in this book--when used in combination with other antiretroviral agents--have extended and improved the lives of those living with the virus in many areas of the developed world. Their use has helped us understand the disease and to stimulate further AIDS research, the impact of which will be more global." This is a highly recommended book for all academic and health science libraries.
1081. AIDS Movie: Representing a Pandemic in Film and Television, by Kylo-Patrick R. Hart. 2000. Haworth Press, 10 Alice St., Binghamton, NY 13904-1580. 120p., bibliog., index. ISBN 0-7890-1107-7, 0-7890-1108-5pbk. $39.95, $27.95pbk. (Descriptors: AIDS in Motion Pictures)
Beverly Hills 90210 made a disaster of representing AIDS as a leading cause of death among young Americans of all sexual orientations and race. It instead depicted the character with AIDS as a gay white male character named Jimmy who disappeared after three weeks and was never mentioned again. This stereotyping of AIDS caused the author to devote three years to locating and analyzing as many representations of AIDS in American movies as he could find. He hopes that what he found will "guide the creators of influential media messages in producing more effective representations of HIV/AIDS that can help stem the tide of the AIDS pandemic as we enter its third decade and (if necessary) beyond." Of the 40 AIDS movies, he analyzed 32. This is an interesting book that provides some well-documented facts on the depiction of AIDS in U.S. movies, most of which is stereotyped as the gay white male. A recommended book for all academic libraries.
1082. Small, Good Thing: Stories of Children with HIV and Those Who Care for Them, by Anne Hunsaker Hawkins. 2000. W. W. Norton, 500 Fifth Ave., New York, NY 10110. 286p., bibliog. ISBN 0-393-04944-2. $23.95. (Descriptors: Children; Patients; Biography; Popular Works)
There have been many books written by physicians about their adult patients such as Abraham Verghese's My Own Country, Abigail Zuger's Strong Shadows, Peter Selwyn's Surviving the Fall, and Daniel Baxter's The Least of These My Brethren. There have not been any written about the children that physicians and caregivers have cared for. This is the book about those young and courageous people. The book contains six extended narratives. "Each begins with a vignette of a clinic visit, a reconstruction of conversations and events based on lengthy notes I took during the actual visit." These are stories about children with HIV and their caregivers. They are moving stories that make you wonder why this dreadful virus has decided to raise its ugly head and infect young people such as it has. It is a book that anyone who has doubts about why we are spending so much money on research should read and re-read. Maybe they will then understand what it is to be like to have the virus that Angelina Morales has or Carlos or Tommy Wheeler or Alyssa. This is a highly recommended book for all school and public libraries and a research source for academic libraries.
1083. Nutrition and AIDS, 2nd edition edited by Ronald R. Watson. 2001. CRC Press, 2000 N.W. Corporate Blvd, Boca Raton, FL 33431. 231p., bibliog., index. (Modern Nutrition). ISBN 0-8493-0272-2. $131.95. (Descriptors: Nutritional Aspects; Dietary Supplements)
Proper nutrition is one key to fighting the HIV virus. Without proper nutrition, immunosuppressive conditions can take over and prevent any drug therapies from working the way they should. Individuals have to eat right, at the right time, and supplement their nutrition with dietary supplements. "The goal of this book is to define recent advances in understanding the nutritional deficiencies of AIDS patients and explore the ways nutritional and dietary changes and herbal medicines benefit or harm them." A further goal "is to provide the most current, concise scientific appraisal of the efficacy of nutrients, foods, and herbal (alternative) medicines in preventing or treating AIDS and its symptoms and improving the quality of life."
The 15 chapters cover: "Wasting and AIDS in the Era of Highly Active Antiretroviral Therapy," "Supplementation and Undernutrition Affect Survival in Murine AIDS," "Antioxidants in Human AIDS," "Trace Elements, Free Radicals, and HIV Progression," "Use of Herbs and Non-Nutritive Supplements in HIV- Positive and AIDS Patients," "AIDS and Food Safety," "Thiols to Treat AIDS," "Drugs of Abuse Modulate Immune and Nutritional Status in AIDS," "Cigarette Smoking and AIDS," "Lipodystrophy: The Most Recent Development in HIV Nutrition Care," "Vitamins in HIV Infection," "Nutrition and HIV/AIDS Patients in Japan," "Nutrition and HIV Infection/AIDS in Sub-Saharan Africa," "Traditional and Popular Uses of Food as Therapy for HIV/AIDS," and "HIV and Infant Growth."
These are well written and easy to understand essays that provide the results of tests and studies that are ongoing throughout the world. There is no doubt that proper nutrition is an aid in combating the virus and the more that individuals realize this the better life those who are HIV positive will live. This is a highly recommended book for all heal science libraries and would be a good resource for academic libraries.
1084. AIDS Pathogenesis, edited by Hanneke Schuitemaker, Frank Miedema. 2000. Kluwer Academic Publishers, P.O. Box 17, 3300 AA Dordrecht, The Netherlands. 282p., illus., bibliog., index. (Immunology and Medicine Series, v. 28). ISBN 0-7923-6196-2. $133.00. (Descriptors: Pathogenesis; Dementia; Therapy)
This book is a collection of research articles concerned with the development of AIDS in humans or the pathogenesis of AIDS in humans. Each year more and more is known about AIDS. Unfortunately, not enough is yet known to conquer this virus and prevent it from killing thousands and thousands of individuals worldwide. Each researcher in performing his or her research unlocks a small part of the knowledge about the virus and passes that knowledge along to other researchers in the hope that the cumulated knowledge will help to discover a cure or vaccine. The articles in this book are intended to add to what is already known and possibly create more research avenues in the study of this complex virus and all the complications that it creates. The largest number of the articles are by researchers from the Netherlands, but other parts of the world are represented such as Sweden, France, Denmark, United States, Australia, Italy, Canada, and the United Kingdom.
Topics covered in the articles include HIV-1 transmission, biological variability of HIV-1, long-term non-progressive HIV infection, opportunistic infections, AIDS dementia complex, Anti-retroviral therapy and resistance to anti-retroviral drugs, prognostic markers and immunological reconstitution during HIV-1 infection and HIV-viral load. These are important articles that will be of interest to anyone who is doing research on the HIV virus. It is a highly recommended book for all academic and health science libraries.
1085. Personal and the Political: Women's Activism in Response to the Breast Cancer and AIDS Epidemics, by Ulrike Boehmer. 2000. State University of New York Press, State University Plaza, Albany, NY 12246. 208p., bibliog., index. ISBN 0-7914-4550-Xpbk. $18.95pbk. (Descriptors: Breast Cancer; Political Aspects; Women Political Activists)
This is a book about activism as it touches on breast cancer and AIDS. It tells of the conflicts that individuals face when they support both types of activism. When anyone supports something such as breast cancer or AIDS in the form of walks, concerts, etc., the immediate reaction from those who have not ever supported such activism is that "Do you have cancer?" or "Do you have AIDS?" The author has done extensive interviewing to compare activists in the AIDS and breast cancer movements. She has shown the similarities and differences between activists from the two movements. Probably the most important finding is that women are motivated by both personal and political reasons.
The book begins with a history of AIDS and breast cancer activism followed by a definition of activism and activists. It then delves into the political culture of AIDS and breast cancer activism; the personal and the political aspects of such activism, and finally the diversity and movement strategies that each activism uses. This is a very interesting look at how women activists become involved, why they become involved, and how they can change along the way and become active in more than one cause. A recommended book for all academic libraries.