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University of Illinois at Chicago University Library

Library of the Health Sciences
Peoria

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P.O. Box 1649, Peoria Illinois 61656-1649 | Phone: (309)671-8490 | Fax: (309)671-8495

PICO Levels
of Evidence Searching MEDLINE Clinical Filters Other EBM
Databases EBM
Publications WEB Internet Resources HOME

Evidence Based Medicine - UIC
Library -
University of
Illinois at Chicago


Sample MEDLINE Searches

These sample MEDLINE searches will give you practice using MeSH, applying clinical filters, and putting limits on your search retrieval. Be aware that different MEDLINE search systems have unique functions and commands.


A Sample MEDLINE Search on Therapy

What is the evidence for the use of antibiotics for treating otitis media in children?

#1 Otitis Media[MeSH]

Explode the MeSH term Otitis Media to include all types. (PubMed explodes automatically).

Drug Therapy [sh]

Add the subheading Drug Therapy to focus in on this specific aspect of the subject.

#2 Antibiotics [MeSH]

Explode the MeSH term Antibiotics to include all antibiotics.

#1 AND #2

Combine terms with AND to retrieve articles dealing with both subjects.

Randomized Controlled Trial [pt]

Limit to a specific publication type for clinically relevant studies.

Child

Limit the search to the specific age group concerned.

English

Limit the search to English if you wish to eliminate foreign language articles.

Clinical Queries

Use PubMed's Clinical Queries to easily limit to Systematic Reviews (there are over 100 RCTs on this topic).

A Sample MEDLINE Search on Diagnosis

Are there any evidence based articles on the differential diagnosis of Alzheimer's Disease?

#1 Alzheimer Disease [majr]

Limit the MeSH term to Major focus.

#2 Dementia, Senile [MeSH]

closely related term

#1 OR #2 = #3

OR retrieves one or both terms

#4) Sensitivity and Specificity [MeSH]

Explode the MeSH term to include more specific terms such as Predictive Value of Tests.

#5 Differential Diagnosis [MeSH]

Differential Diagnosis is a useful MeSH term with closely related diseases.

#3 AND #4 AND #5

Combine terms with AND.

Clinical Trials [PT]

Limit using the Clinical Trials Publication Type.

A Sample MEDLINE Search on Prognosis

What is the prognosis for a successful pregnancy in a young woman with Systemic Lupus Erythamatosus?

#1Lupus Erythematosus, Systemic [MeSH]

Limit the MeSH term to Major Focus

#2 Pregnancy [MeSH] OR Pregnancy Outcome [MeSH]

OR related terms.

#3 Cohort Studies [MeSH]

Select Cohort Studies for a Prognosis Search.

#4 Prognosis [MeSH]

The MeSH term Prognosis is effective in this search.

( #1 AND #2) AND ( #3 OR #4)

Combine search history terms with AND and OR. "Nest" combined terms with parentheses.

A Sample MEDLINE Search on Quality Improvement

Are there any evidence based practice guidelines on the use of mammography in screening for breast cancer?

#1 Breast Neoplasms [majr]

EXPLODE the MeSH term Breast Neoplasms and Limit to Major Focus.

#2 Mammography [majr]

EXPLODE the MeSH term Mammography and Limit to Major Focus.

#1 AND #2

Combine terms with AND to retrieve articles dealing with both concepts.

Practice Guideline[pt] OR Clinical Guideline[pt] OR Consensus Development Conference[pt]

Limit the search to these publication types to find published evidence/consensus on this practice.

Change Databases and Rerun Search

Check other databases such as www.guidelines.gov to find published guidelines.

A Sample MEDLINE search on Etiology

Does hormone replacement therapy increase the risk for pulmonary embolism in postmenopausal women?

#1 Pulmonary Embolism [majr]

Limit the MeSH term to Major Focus.

etiology [sh] OR epidemiology [sh]

Attach subheadings useful in etiology questions.

#2 Hormone Replacement Therapy [MeSH]

Explode Hormone Replacement Therapy, which includes Estrogen Replacement Therapy.

#1 AND #2

AND combines these concepts.

PICO Levels
of Evidence Searching MEDLINE Clinical Filters Other EBM
Databases EBM
Publications WEB Internet Resources HOME


This page is maintained at www.uic.edu/depts/lib/lhsp/resources/ebm.shtml by Jo Dorsch, UIC Library of the Health Sciences-Peoria. Please send comments to Jo Dorsch jod@uic.edu.

Last updated: Tuesday, 12-Apr-2005 13:09:33 CDT
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