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Sample MEDLINE Searches
These sample MEDLINE searches will give you practice using MeSH,
applying clinical filters, and putting limits on your search retrieval.
Be aware that different MEDLINE search systems have unique functions and
commands.
A Sample MEDLINE Search on Therapy
What is the evidence for the use of antibiotics for
treating otitis media in children?
#1 Otitis Media[MeSH] |
Explode the MeSH
term Otitis
Media to include all types. (PubMed explodes automatically). |
Drug Therapy [sh] |
Add the
subheading Drug Therapy to
focus in on this specific aspect of the subject. |
#2 Antibiotics
[MeSH] |
Explode the MeSH term
Antibiotics to include all antibiotics. |
#1 AND #2 |
Combine terms with AND to
retrieve articles
dealing with both subjects. |
Randomized Controlled Trial
[pt] |
Limit to a specific
publication type for clinically relevant studies. |
Child |
Limit the search to the
specific age
group concerned. |
English |
Limit the search to
English if you wish
to eliminate foreign language articles. |
| Clinical Queries |
Use PubMed's Clinical Queries to easily limit to
Systematic Reviews (there are over 100 RCTs on this topic). |
A Sample MEDLINE Search on Diagnosis
Are there any evidence based articles on the
differential diagnosis of Alzheimer's Disease?
#1 Alzheimer Disease
[majr] |
Limit the MeSH term to Major
focus. |
#2 Dementia, Senile
[MeSH] |
closely
related
term |
#1 OR #2 = #3 |
OR retrieves
one or both
terms |
#4) Sensitivity and Specificity
[MeSH] |
Explode the MeSH
term
to include more specific terms such as Predictive Value of
Tests. |
#5 Differential Diagnosis
[MeSH] |
Differential Diagnosis is a useful MeSH term with closely
related diseases. |
#3 AND #4 AND #5
|
Combine terms with AND. |
Clinical Trials [PT] |
Limit using the Clinical Trials Publication
Type. |
A Sample MEDLINE Search on Prognosis
What is the prognosis for a successful pregnancy in a
young woman with Systemic Lupus Erythamatosus?
#1Lupus Erythematosus, Systemic
[MeSH] |
Limit the MeSH term to
Major Focus |
#2 Pregnancy [MeSH] OR Pregnancy Outcome
[MeSH] |
OR
related
terms. |
#3 Cohort Studies
[MeSH] |
Select
Cohort Studies for a
Prognosis Search. |
#4 Prognosis [MeSH] |
The MeSH
term Prognosis is effective
in
this search. |
( #1 AND #2) AND ( #3 OR
#4) |
Combine search history terms
with AND and OR. "Nest" combined terms with
parentheses. |
A Sample MEDLINE Search on Quality Improvement
Are there any evidence based practice guidelines on the
use of mammography in screening for breast cancer?
#1 Breast Neoplasms [majr]
|
EXPLODE the MeSH term
Breast
Neoplasms and Limit to Major Focus. |
#2
Mammography [majr] |
EXPLODE the MeSH term Mammography and
Limit to
Major
Focus. |
#1 AND #2 |
Combine terms
with AND to retrieve articles
dealing with both concepts. |
Practice Guideline[pt] OR Clinical
Guideline[pt] OR Consensus
Development Conference[pt] |
Limit the search to these
publication
types to find published evidence/consensus on this practice. |
Change Databases and Rerun
Search |
Check other databases
such as www.guidelines.gov to find published
guidelines. |
A Sample MEDLINE search on Etiology
Does hormone replacement therapy increase the risk for pulmonary
embolism in postmenopausal women?
#1 Pulmonary Embolism [majr] |
Limit
the MeSH term to
Major Focus. |
etiology [sh] OR epidemiology
[sh] |
Attach subheadings useful in etiology
questions. |
#2 Hormone Replacement Therapy
[MeSH] |
Explode Hormone Replacement Therapy,
which includes Estrogen Replacement Therapy. |
#1 AND #2 |
AND
combines these
concepts. |
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This page is maintained at www.uic.edu/depts/lib/lhsp/resources/ebm.shtml
by Jo
Dorsch, UIC
Library of the Health Sciences-Peoria. Please send comments to Jo Dorsch jod@uic.edu.
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Last updated: Tuesday, 12-Apr-2005 13:09:33 CDT
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