Clinical Interface Core (CIC)

The Clinical Interface Core and its Clinical Research Center (CRC) at UIC provides a comfortable, safe and effective environment to conduct research involving human subjects. This is achieved by providing the necessary environment, equipment and personnel to optimize research goals. The CIC fosters education in clinical research at all levels of training.
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Protocols

Current Protocols
Completed Protocols

Current Protocols

CRC Protocol # Project Title PI Last Name PI First Name
2012-21 Oxytocin vs Placebo in Autism: Examining Cognitive Effects Jacob Suma
2012-16 Changes in Oxytocin from Pregnancy to after Birth Bell Aleeca
2012-12 Surgical Menopause and Risk for Premature Aging of the Optic Nerve and Glaucome Thasarat Vajaranant
2012-09 Contraceptive Decision-Making: Women's Preferences for IUD-related Health States Harwood Bryna
2012-05 A Phase 3 Randomized, Double Blind, Vehicle Controlled Study Investigating the Ssafety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers Ennis William
2012-03 Regulation of CYP2D6 in Pregnancy and its impact on Perinatal Depression Jeong Hyunyoung
2011-50 Dyspnea in Heart Failure with Preserved Ejection Fraction Vuckovic Karen
2011-49 LIPS-A: Lung Injuray Prevention Study with Aspirin Sadikot Ruxana
2011-48 A Randomized, Open Label, Wait-list Control Trial to Evaluate the Efficacy of Intravenous Iron in Older Adults with Unexplained Anemia and a Serum Ferritin Between 20 and 100 ng/mL Gordeuk Victor
2011-47 Effects of Aging and Physical Activity on Cardiovascular Responses to the Flu Vaccine Fernhall Bo
2011-45 DCVax-Brain for Treatment of Glioblastoma Multiforme Watson Karriem
2011-43 Laporoscopic Adjustable Gastric Banding (Lap-Band) Holterman Mark
2011-40 Neuroendocrine Correlates of Stress and Resilience in Major Depression Ajilore Olusola
2011-38 B Braun, Prontosan wound care Ennis William
2011-37 Roche 24 week Weiden Peter
2011-36 Seaside Open Label Extension Study Cook Edwin
2011-35 A Multicenter, Randomized, Double-Blnd, Pacebo-Controlled, Parallel Group Study to Evaluate the Efficacy, Safety, and Tolerability of Ixmyelocel-T in Subjects with Crticial Limg Ischemia and No Options for Revascularization Ennis William
2011-34 Effects of Oral QLT091001 in Subjects with Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Fishman Gerald
2011-29 Pathways to Preterm Birth: Stress, Inflamation, and Cervical Remodeling White-Traut; McFarlan Rosemary; Barbara
2011-28 Alexion Eculizumab Thielke Patty West
2011-27 Phase III Intravitreal Injections of DE-109 for the Treatment of Active, Non-infectious Uveitis of the Posterior Segment of the Eye Goldstein Debra
2011-26 CAMS Menopause Study Rubin Leah
2011-24 Roche 12 week Weiden Peter
2011-23 ASKP1240 Kidney Transplant Study West Patricia
2011-20 BAILE: Boosting Activity In Latino Elderly Marquez David
2011-17 TrialNet Ize-Ludlow Diego
2011-16 Obesity and Mealtime Behaviors in a Diverse Sample of Low-income Families Fitzgibbon Marian
2011-12 Vitamin D, Inflammation and Relations to Insulin Resistance and Trip-Induced Falls in Obese Pre-Menopausal Women Nguyen Van
2011-08 Study of Novel Genetic Variations in the Vitamin K Epoxide Reductase Gene Cavallari Larisa
2011-07 LCP - Tacro 3002 West Patricia
2011-05 Health Promoters and Pharmacists in Diabetes Team Management Gerber Ben
2011-04 Seaside Autism Study Cook Edwin
2010-66 SciClone Feldman Lawrence
2010-59 Retinoid & Carotenoid Depletion in Patients at High-Risk for Liver Cancer Gann Peter
2010-58 Low Carb Diet Study Phillips Shane
2010-56 Regulatory T Cells in ALS Rowin Julie
2010-55 TRIO Abcarian Herand
2010-51 Regulatory T Cells in the Pathogenesis of Human Myasthenia Gravis Meriggioli Matthew
2010-49 Measurement of Insulin Resistance on Older Adolescents and Young Adults with Type 1 Diabetes-Pilot Study Nemeth Pamela Martyn
2010-48 Intravenous Carbamazepine in Adults with Epilepsy Fischer James
2010-43 Efficacy of Massage Therapy in Attenuating Vascular Dysfunction After Exertion-Induced Muscle Injury Phillips Shane
2010-38 Vitamin D Deficiency and Treatment in Male Veterans at Risk for Diabetes Barengolts Elena
2010-37 GM-CSF Myasthenia Gravis Meriggioli Matthew
2010-35 Developing Brain Function in Adolescent Bipolar Disorder Bishop Jeff
2010-34 SPRINT Lash James
2010-29 Centering Pregnancy for Healthy Pregnancy Vonderheid Susan
2010-22 "Identification and Impact of Age Related Changes in Neutrophilis During an Asthma Exacerbation" Nyenhuis Sharmilee
2010-13 ”Pilot Study – Mast Cell, Macroshage & Eosinophil Interactions in Asthma” Christman John
2010-12 CONCERT Lee Todd
2010-10.1 Efficacy of Lithium in Pediatric Mood Disorder – “CoLT 2” Pavuluri Mani
2010-05 Effects of Estradiol and Soy on Menopausal Symptoms Maki Pauline
2010-03 A weight loss intervention for African-American breast cancer survivors Stolley Melinda
2010-01
Resistance Training, Exertional Hypertension, and Vascular Dysfunction
Phillips Shane
2009-24 Cortical/Subcortical Circuits in Late-Life Depression Kumar Anand
2009-23
Mycophenolate vs. Oral Cyclophosphamide in Scleroderma Interstitial Lung Disease
Volkov Suncica
2009-22
External Nutrition in ALS patients with Ventilatory failure: minimizing the work of breathing
Rowin Julie
2009-19 Myelin, Glia and Depression in Type 2 Diabetes Kumar Anand
2009-17
Phase II Study of Single-Agent Cetuximab for Treatment of High-Risk Pre-Malignant Upper Aerodigestive Lesions
Epstein Joel
2009-12
Clinical Phenotyping Resource and Biobank Core (C-PROBE)
Perumal Kalyani
2009-10 Affective Neuroscience of Pediatric Bipolar Disorder Bishop Jeff
2009-05
Effects of Carrageenan-Elimination Diet on Ulcerative Colitis Disease Activity
Tobacman Joanne
2009-01
Adiposity and Outcomes of Clinically Localized Prostate Cancer
Freeman Vince
2008-05 CIT 07 Islet Alone - Phase 3 Oberholzer Jose
2008-04 CIT06 Islet After Kidney Transplant Oberholzer Jose
2008-03 CIT02 Strategies to Improve Long Term Islet Graft Survival Oberholzer Jose
2007-10 Exertional Hypertension and Vascular Dysfunction Phillips Shane
2007-07
Adipose Tissue and Insulin Resistance in Polycystic Ovary Syndrome
Sam Susan
2007-04 Chronic Kidney Disease in Children Study John Eunice
2007-03
Islet Transplantation in Type I Diabetic patients Using the UIC Protocol
Oberholzer Jose
2005-14
Hispanic Chronic Renal Insufficiency Cohort "CRIC" Study
Lash James
2004-14
Islet Transplantation in Type 1 Diabetic Patients using the UIC Protocol
Oberholzer Jose
2003-09 Chronic Renal Insufficiency Cohort Study Lash James
2003-08 Neurobiology of Pediatric Unipolar and Bipolar Disorders: Role of Cellular Signaling Pandey Ghanshyam
2002-21 PKC Substrates & transcription factors in mood disorders Pandey Ghanshyam


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Completed protocols

CRC Protocol # Project Title PI Last Name PI First Name
2011-27 Phase III Intravitreal Injections of DE-109 for the Treatment of Active, Non-infectious Uveitis of the Posterior Segment of the Eye Goldstein Debra
2011-16 Obesity and Mealtime Behaviors in a Diverse Sample of Low-income Families Fitzgibbon Marian
2010-23 Phase 3, Double-Blind, Randomized, Multicenter, Placebo-Controlled, Dose Optimization Study Evaluating the Tolerability and Efficacy of AM and PM Once Daily Dosing with Extended-Release Guanfacine Hydrochloride in children 6-12 with Diagnosis of ADHD Stein Mark
2010-20 Cognition and Brain Functions in Psychiatric Disorders Sweeney John
2010-19
Bipolar & Schizophrenia Consortium for Parsing Intermediate Endophenotypes
Sweeney John
2010-16
Vitamin D, Inflammation and Relations to Insulin Resistance and Trip-Induced Falls in Obese Pre-Menopausal Women
Nguyen Van
2010-07
Obesity Reduction Black Intervention Trial (ORBIT)
Fitzgibbon Marian
2009-28
A Double-Blind, Double-Dummy, Randomized, Active-Comparator, Arthritis Non-Inferiority Study of LT-NS001 versus NaprosynR for 12 wks in Osteoarthritis Patients to Compare Endoscopic Gastric Ulcer Rates ( LT Pharmaceuticals)
Goldstein Jay
2009-27
Open-Label Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-Steroidal Anti-Inflammatory Drug Treatment Protocol#: HZ-CA-401 (Horizon)
Goldstein Jay
2009-26
A 6-Month, Phase 3, Randomized, Double-Blind, Parallel-Group, Controlled, Multi-Center Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PA32540 or Enteric Coated ASA 325 mg Subjects at Risk for Ulcers (Pozen)
Goldstein Jay
2009-25
THE IMPROVE TRIAL: Improving Pain Management and Outcomes with Various Strategies of Patient-Controlled Analgesia (PCA)
Labotka Richard
2009-21
A Phase 3, Open-Label, Multicenter, Prospective, Randomized Study of the Efficacy and Safety of Conversion From Prograf Capsules Twice Daily to LCP-TACRO Tablets Once Daily for the Prevention of Acute Allograft Rejection in Stable Kidney Transplant Patients
West Patricia
2009-18
Study to evaluate the safety, tolerability and pharmacokinetics of HQK-1001 in subjects with sickle cell disease
Labotka Richard
2009-17
Phase II Study of Single-Agent Cetuximab for Treatment of High-Risk Pre-Malignant Upper Aerodigestive Lesions
Epstein Joel
2009-15
A Phase 2, Multi-center, Randomized, Double-blind, Placebo-controlled, Dose Ranging Study to Assess the Safety and Efficacy of SCV-07 for the Delay to Onset of Severe Oral Mucositis in Subjects Receiving Chemoradiation Therapy for the Treatment of Cancers of the Head and Neck
Epstein Joel
2009-08
A Prospective, Multi-center, Randomized, Controlled, Third Party-Blinded Study of StratticeT Fascial Inlay to Prevent Parastomal Hernia Formation in Patients Undergoing Surgery for Permanent Abdominal Wall Ostomies (PriSm)
Abcarian Herand
2009-04
Study of the Pharmacokinetics, Safety, Efficacy, & Tolerability of Menantine in Pediatric Patients with Autism
Najjar Fedra
2008-12
A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Group, Active-Control Studyto Evaluate the Safety and Efficacy of a Single Administration of SKY0402 for Prolonged Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy
Singer Marc
2008-11
A PHASE 2, OPEN-LABEL, MULTI-CENTER, RANDOMIZED TRIAL TO DEMONSTRATE THE PHARMACOKINETICS OF LCP-TACRO TABLETS ONCE DAILY AND PROGRAFR CAPSULES TWICE DAILY IN ADULT DE NOVO KIDNEY TRANSPLANT
West Patricia
2008-10
Randomized, double-blind, placebo controlled study of the safety and efficacy of Marinol in patients with obstructive sleep apnea syndrome
Carley David
2008-09 Effects of Corticosteroids on Oral Healing Enegland Chris
2008-08
A Phase II, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety and Efficacy of Ipamorelin Compared to Placebo for the Management of Post-Operative Ileus in Patients Who Have Undergone Partial Bowel Resection Surgery
Singer Marc
2008-07
A Double-Blind, Randomized, Active Comparator Study of LT-NS001 versus Naprosyn for Seven Days in Healthy Subjects with Endoscopic Evaluation
Goldstein Jay
2008-06
Treatment of Pulmonary Hypertension and Sickle Cell Disease with Sildenafil Therapy Walk-PHaSST
Schramufnagel Dean
2008-02
Safety and Efficacy of Alefacept in de novo Kidney Transplant Patients
West Patricia
2007-08
A Sequential Open-Label Study of the Pharmacokinetics and Safety of Intravenous Carbamazepine Relative to Oral Carbamazepine in Adult Patients with Epilepsy (Ovation Protocol 1015, Amendment #2)
Fischer James
2005-24
Measuring and Predicting Responses to Atomoxetine (ATX) and Methylphenidate (MPH)
Stein Mark
2003-08
Monoamine receptor function in children with mood disorders
Pandey Ghanshyam
2002-21 PKC Substrates & transcription factors in mood disorders Pandey Ghanshyam

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Completed Protocols as GCRC

To view the protocols completed in CRC (prior to CCTS funding) click here