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UIBiorepository
The Use of Human Biospecimens in Clinical and Translational Research
A growing collection of human tissue and non-tissue samples centralized in the UI Biorepository is answering a burgeoning demand for readily accessible biospecimens including tissues, blood, urine and bone. Clinical and translational investigators increasingly look to consolidation of such samples to facilitate studies involving proteomics and genomics, genome screening (sequencing) used in drug discovery and genome-wide association (GWAS), all of which have been made possible by new technology. GWAS can help researchers recognize patterns of disorders, which provide clues in determining individual risk of developing particular disorders or diseases.
The CCTS provides support for the Biorepository through collaboration with its Bioinformatics Core (BI) and use of the BI Clinical Research Data Warehouse, which consolidates data from a variety of sources that investigators might not otherwise access.
Biorepository services include:
Whole blood processing
- iPrep genomic DNA isolation
- RNA isolation
- PBMC isolation
- Serum separation
- Buffy coat isolation
- Whole blood freezing
Tissue
Sample preparation, including frozen section fixation or chemical
fixation, dehydration, embedding (FFPE), sectioning, staining.
Frozen or FFPE tissue samples can be retrieved from the archives, with
roughly 50 types of tissue available.
Other tissue procedures can be determined, in collaboration with pathology.
Protocols can be adopted on other samples, e.g., semen, saliva/sputum.
Learn more about the UI Biorepository at http://biorepository.uic.edu or contact
Lauren Walsh, Clinical Interface Coordinator - CCTS
Phone : 312-413-7316
Email : laurenw@uic.edu
Bernie Santarsiero, Associate Director - Biorepository
Phone : 312-413-0339
Email : UIBiorep@uic.edu