Macromolecular Structure Facility (RRC/MSF)
The MSF houses instrumentation to collect and analyze x-ray diffraction images from single crystal samples. Typically a protein can be crystallized under certain conditions, and flash-cooled to liquid nitrogen temperatures. When the sample is exposed to x-rays, a pattern of deflected x-rays will be generated, and that pattern is representative of the electron density of the protein, much like an atomic image of the protein. Several researchers on campus take advantage of this technique to determine an atomic representation of their protein target.