Fundamentals of Immunology & Microbiology MIM 425 - Spring '09
Course Director: Ananda Chakrabarty , Ph.D.
Course Objectives:
Students learn the basic properties of medically relevant bacteria, viruses and fungi and how these organism cause disease. The course covers basic aspects of microbiology, including bacterial structure and function, genetics, drug resistance, mechanisms of virulence, viral structure and viral replication. Several of the most important pathogens are covered in detail with emphasis on integrating the properties of the microbe, epidemiology and the mechanisms of pathogenesis.
Students in the course learn mechanisms of the body's immune resistance to infectious viruses and pathogenic bacteria. The course covers the structure of antibodies, the cellular mechanisms of response, and the genetic origin of the body's capacity to respond immunologically to an extraordinarily wide variety of foreign substances.
Textbook:
- Janeway's Immunobiology by Murphy, Travers, & Walport ; 7th Edition; Garland Science
- Medical Microbiology by Murray, Rosenthal, & Pfaller; 5th Edition; Elsevier Mosby
| # | Date | Time | Lecture Title | Lecturer |
|---|---|---|---|---|
| 1 | 3/10 | 9:30 | Introduction to Immunology (ch 1-2) | Prabhakar |
| 2 | 3/10 | 10:30 | Introduction to Immunology (ch 1-2) | Prabhakar |
| 3 | 3/11 | 9:30 | Introduction to Immunology (ch 1-2) | Prabhakar |
| 4 | 3/12 | 9:30 | Complement (ch 2) | Ucker |
| 5 | 3/12 | 10:30 | Antigen Recognition by B Cells (ch 3) | Kenter |
| 6 | 3/13 | 8:30 | Generation of Diversity I | Kenter |
| 7 | 3/16 | 9:30 | Rearrangements and Development (ch 7) | Kenter |
| 8 | 3/17 | 9:30 | Generation of Diversity II (ch 4) | Kenter |
| 9 | 3/17 | 10:30 | The Humoral Immune Response (ch9) | Kenter |
| 10 | 3/18 | 9:30 | MHC Complex and Its Functions (ch 5) | Bouvier |
| 11 | 3/19 | 9:30 | Antigen Presentation to T Cells (ch 5) | Bouvier |
| 12 | 3/20 | 9:30 | Antigen Recognition by T cells (ch 3) | Bouvier |
| 13 | 3/20 | 10:30 | Development of Lymphocytes (ch7) | Ucker |
| 14 | 3/23 | 9:30 | Lymphocyte signaling-1 (ch6) | Kanteti |
| 15 | 3/24 | 9:30 | Lymphocyte signaling-II (ch6) | Kanteti |
| 16 | 3/24 | 10:30 | Cell-Mediated Immunity I (ch 8) | Chen |
| 17 | 3/25 | 9:30 | Cell-Mediated Immunity II (ch8) | Chen |
| 3/26 | 9:00 - 10:20 | Review | All Participating faculty as above | |
| 3/26 | 1:30 | Midterm Exam | ||
| 18 | 3/31 | 9:30 | Bacterial structure, variety | Volz |
| 19 | 4/1 | 9:30 | Bacterial Growth, Nutrition, Death | Volz |
| 20 | 4/2 | 9:30 | Bacterial nutrition,metabolism | Volz |
| 21 | 4/2 | 10:30 | Control of Microbial Growth | Chakrabarty |
| 22 | 4/3 | 9:30 | Antibiotics:Mechanisms of actions and Bacterial Resistance |
Federle |
| 23 | 4/6 | 9:30 | Bacterial Genetics | Freitag |
| 24 | 4/7 | 9:30 | Bacterial Genetics | Freitag |
| 25 | 4/8 | 9:30 | Bacterial Pathogenesis | Freitag |
| 26 | 4/9 | 9:30 | Pathogenesis-mechanisms | Freitag |
| 27 | 4/10 | 9:30 | Gram Positive Cocci | Federle |
| 28 | 4/13 | 9:30 | Gram Positive Cocci | Federle |
| 29 | 4/14 | 9:30 | Pathogenesis-Selected Enterics (E. coli, Salmonella, and Shigella) |
Chakrabarty |
| 30 | 4/15 | 9:30 | RespiratoryInfections(Burkholderia, Pseudomonas,Legionella and Bordetella) |
Chakrabarty |
| 31 | 4/15 | 10:30 | Viral structure and diversity | Rong |
| 32 | 4/16 | 9:30 | Viral Replication | Rong |
| 33 | 4/16 | 10:30 | Viral Pathogenesis | Cook |
| 34 | 4/17 | 10:30 | Bioterrorism | Cook |
| 5/1 | 8:30-12:20 | Final Exam |
Lecture Room 423 CMW