Infection & Immunity for MIM 426 - Fall '09

Course Director: Edward P. Cohen , M.D.

Course Objectives:

Students learn the basic properties of medically relevant bacteria, viruses and fungi and how these organisms cause disease.  Clinical aspects of infectious diseases are stressed. In addition, aspects of the immune response such as autoimmunity, hypersensitivity defects in the immune system, and cancer immunology are discussed.  A majority of the important pathogens are covered in detail with emphasis on integrating the properties of the microbe, epidemiology, mechanisms of pathogenesis, clinical diagnosis, and disease outcome.  The laboratory sessions are designed to introduce the student to diagnostic principles as well as reinforce information obtained in lectures. Interactive case presentations will be given to lab groups to focus on infectious diseases.

Textbook:

  1. Janeway's Immunobiology by Murphy, Travers, & Walport ; 7th Edition; Garland Science
  2. Medical Microbiology by Murray, Rosenthal,  & Pfaller; 5th Edition;  Elsevier  Mosby

Optional Textbooks:

Review of Medical Microbiology and Immunology by Levinson, McGraw Hill-Lange

Diagnostic Microbiology: Koneman, et al.,Color Atlas and Textbook of Diagnostic Microbiology, 5th ed., Lippincott, 1997 for laboratory sessions

 

Unless otherwise noted, all lectures are from 11:30 AM to 12:20 PM in Room 221 CMW

#

DATE   

TOPIC  

INSTRUCTOR
1.

Aug 17 

Innate    Immunity

Cohen
2.

Aug 18 

Adoptive Immunity

Cohen
3.

Aug 19 

Allergy and Hypersensitivity-1

Cohen
4.

Aug 20 

Allergy and Hypersensitivity-2

Cohen
5.

Aug 21 

Immuniodeficiencies

Rich
6.

Aug 24 

Bacterial Identification in Clinical Microbiology

Janda
7.

Aug 25 

Neisseria and Hemophilus           

Janda
8.

Aug 26 

Fastidious Gram Negative Bacilli I              

Janda
9.

Aug 27 

Fastidious Gram Negative Bacilli II

Janda
10.

Aug 28 

Anaerobes         

Janda
11.

Aug 31 

Vaccination        

Hendrickson
12.

Sept 1   

Vibrionaceae, Campylobacter Heliobacter         

Freitag
13.

Sept 2   

Non fermenting Gram negatives  

Matsumura
14.

Sept 3   

Enterobacteria-1              

Kenney
15.

Sept 4   

Enterobacteria-2              

Kenney
16.

Sept 8   

Autoimmunity-1 

Cohen
17.

Sept 9   

Autoimmunity-2 

Cohen
18.

Sept 10

Transplantation 

Cohen
19.

Sept 11

Tumor immunity

Cohen
20.

Sept 15

Aerobic/Facultative Gram-Negative Bacilli I

Janda
21.

Sept 17

Aerobic/Facultative Gram-Positive Bacilli I

Janda
22.

Sept 21

Chlamydia/Mycoplasma

Janda
23.

Sept 22

Mycobacteria     

Cook
24.

Sept 23

Spirochetes        

Hendrickson
25.

Sept 24

Cases                  

Hendrickson
26.

Sept 28

Drug discovery-1              

Chakrabarty
27.

Sept 30

Drug discovery-2              

Chakrabarty
Oct 6 10:30 AM - 12:20 PM Review
Oct 13 1:30 - 4:30 PM Midterm Exam
28.

 Oct 26

 Diagnostic virology - Room 106 CMW            

Janda
29.

 Oct 27

 Pathogenic Fungi

Waterman
30.

 Oct 28

 Pathogenic Fungi

Waterman
31.

 Oct 29

 Human Retroviruses-1

Chen
32.

 Nov 3

 Human Retroviruses-2

Chen
33.

 Nov 4

 Orthmyxoviruses              

Shukla
34.

 Nov 5

 Paramyxoviruses

Shukla
35.

 Nov 10

 Rhabdoviruses  

Shukla
36.

 Nov 11

 Hepatitis viruses B and D              

McLachlan
37.

 Nov 12

 Adeno and Parvo, Papilloma                       

McLachlan
38.

 Nov 16

 Picoraviruses                    

Uprichard
39.

 Nov 17

 Respiratory viruses          

Uprichard
40.

Nov 18

 Hepatitis viruses A and C              

Uprichard
41.

Nov 19

 Herpes-1                            

He
42.

Nov 30

 Herpes-2                            

He
43.

Dec 1

 Failure of host defenses

Chen
44.

Dec 2

 Emerging viral pathogens             

He
Dec 10 1:30 PM Case Studies Exam
Dec 15 8:30 AM - 12:30 PM Final Exam