| Frazier was one of the first groups of American pioneers who created neurosurgery a new branch of general surgery. From early training in surgery, neurology and pathology, he went on to devote himself exclusively to neurosurgery during World War I reporting at one time on 500 cases of peripheral nerve injury and reconstruction and on 200 cases of gunshot wounds of the head. Frazier’s early achievements were in his surgical approach to intracranial and intraspinal tumors. He changed the approach methodology to trigeminal neuralgia surgery. He proved that the pre-ganglionic section of the sensory root of cranial V was a permanent cure for trigeminal neuralgias, as was avulsion of the ganglion. He inaugurated spinal cord surgery for pain and popularized cordotomy. |  |