Born in Spain, he did all his studies there and rose in stature to become Professor of Anatomy at Valencia, later histology in normal and pathologic histology at Barcelona and then to Madrid as Professor of normal histology and pathological anatomy. He and Camillo Golgi received the Nobel Prize in 1906 for introduction of the silver-chromate stain. Later he set out carefully to explore the finer aspects of the brain. With his reduced silver nitrate technique he demonstrated neurons and their connections so easily. His introduction of his gold chloride- mercury bichloride technique to demonstrate astrocytes was a monumental contribution as was his work on degeneration and regeneration of the nervous system later. He will be remembered as a world famous neuropathologist.
Drawing of cortical layers by Cajal

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