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Physiology,
biochemistry, molecular biology, and pharmacology of cardiac
muscle contraction.
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Electrophysiological
studies of dopaminergic neurons of the ventral tegmental
area; drug and neurotransmitter effects; mechanism of
action of alcohol; potassium channels.
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Electrophysiology of neurons of the ventral tegmental area studied in brain slices, actions of ethanol on the central nervous system; electrophysiological actions of drugs of abuse on brain neurons.
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Microperfusion
and electrophysical studies of cellular mechanisms underlying
hormonal action on renal tubular function; renal regulation
of acid-base balance.
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Nuclear
Myosin I. GTPase-myosin interactions in cell signaling.
Vascular biology/gene therapy
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Cardiovascular
physiology, muscle contraction, cardiac energetics, ventricular-arterial coupling,
cardiac pump function.
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Nuclear
magnetic resonance theory and its biomedical applications
at cellular, subcellular and molecular levels.
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JONNA FRASOR
Ph.D., Assistant Professor
1097 COMRB
312-355-2583
jfrasor@uic.edu |
inflammation modulates estrogen receptor activity. In particular, I am interested in the molecular crosstalk between estrogen and cytokine signaling and how this interaction may be involved in the initiation and progression of breast cancer. |
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Molecular
mechanisms of excitation-contraction coupling in skeletal
and cardiac muscle; neuronal regulation of gene expression
in muscle.
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Reproductive
endocrinology, regulation of ovarian and placental function;
molecular mechanism of hormone action.
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Molecular
endocrinology, immune control of male reproductive function,
regulatory mechanisms of Leydig cell steroid hormone biosynthesis,
reproductive immunology and toxicology.
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Regulation
of Ion transport across epithelia; membrane transport,
volume regulation, calcium mineralization, microelectrophysiology.
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Mechanisms
of steroid hormone action; Interaction of thyroid hormones
with receptors and their role in growth and differentiation;
hormonal control of gene expression.
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JOHN
M. KENNEDY
Ph.D., Associate
Professor
332 CMW
312-996-7992
jkennedy@uic.edu
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Regulation
of gene expression in skeletal and cardiac muscle.
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Metabolic
basis for cardiac dysfunction in heart disease; Metabolic
flux regulation by transporter protein and enzyme isoform
expression in cardiovascular disease; NMR spectroscopy
and imaging (MRS / MRI) of cardiac viability and
metabolism; Isotope kinetics; Mitochondrial function and
metabolic communication between subcellular compartments.
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Mechanisms
of nerve growth in synaptic transmission.
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Regulation
of water and electrolyte transport across epithelia: role
of calcium and cyclic nucleotides, electrophysiological,
pathophysiological, biochemical and molecular studies.
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Cellular
neurobiology, neurotransmitter receptors; adenylate cyclase,
GTP-binding proteins, and the cytoskeleton; cyclic nucleotides
and cellular signal transduction.
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Molecular
and subcellular mechanisms involved in muscle growth and
adaptation: cardiac and skeletal.
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LARRY TOBACMAN
M.D., Professor
901
CSB
312-413-1010
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Regulation
of cardiac and skeletal muscle contraction by troponin and
tropomyosin.
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RESEARCH
FACULTY
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SAMUEL
BOATENG
Ph.D., Research Assistant
Professor
E-208 MSB
312-996-7477
sboateng@uic.edu
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Nuclear Magnetic Resonance
localized spectroscopy
Magnetic Resonance microimaging
cardiac imaging
cardiac tagging
myocardial strain analysis
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YUNBO
KE
Ph.D., Research Assistant
Professor
2080 COMTN
312-996-6063
yke@uic.edu
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Function
of P21-Activated Kinase-1 (Pak1) in Heart
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Molecular,
functional and structural aspects of contractile and thin
filament; regulatory proteins in cardiac and vascular
smooth muscle.
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Biochemistry,
physiology, and molecular biology studies integrating
cardiac metabolism, calcium handling, and enzyme expression
in heart disease. Utilizing methods of NMR spectroscopy,
fluorescence microscopy, and in vivo gene transfer.
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Cellular and molecular biology,
biochemistry and pharmacology of phospholipase signaling and the cytoskeleton;
mechanisms of
crossregulation between intracellular signaling and cytoskeletal dynamics.
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BRIAN
B. ROMAN
Ph.D., Research Assistant
Professor
1133 CSB
312-355-1647
broman@uic.edu
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MARIUS
SUMANDEA
Ph.D., Research Assistant
Professor
E-204 MSB
312-996-8906
psuman1@uic.edu
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DALIA
URBONIENE
Ph.D., Research Assistant
Professor
408 CSN
312-996-3749
durboni@uic.edu
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JOHN
S. WALKER
Ph.D., Research Assistant
Professor
2141 COMRB
312-355-0150
jsw9c@uic.edu
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LORI
A. WALKER
Ph.D., Research Assistant
Professor
1125 CSB
312-413-1818
lw7t@uic.edu
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Signal
transduction mechanisms of G protein-coupled receptors in
cardiac myocytes.
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JIANG-ZHOU
YU
Ph.D., Research Assistant
Professor
2160 COMRB
312-413-8240
yuzj64@uic.edu
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