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NIH Lung Biology and Pathobiology Training Faculty

Name/Degree
Rank
Primary (& Secondary)
Appointment(s)
Research Interests
Asrar B Malik., PhD Distinguished Professor and Head Pharmacology
(Center for Lung and Vascular Biology)
Regulation of barrier property of lung endothelial cells; cellular and molecular basis of lung endothelial activation and injury; neutrophil/endothelial interactions.
Steven J. Ackerman, PhD Professor Biochemistry and
Molecular Genetics
(Medicine)
Transcriptional mechanisms regulating development and gene expression; biology of eosinophils and their role in inflammation.
Richard V. Benya, MD Professor Medicine- Section of Digestive Disease and Nutrition Heptahelical G protein-coupled receptor activation mechanisms and their role in cell activation and proliferation.
Scott T. Brady, PhD Professor and Head Cell Biology Molecular motors (kinesins) and regulation of intracellular vesicle trafficking.
David W. Carley, PhD Professor Pharmacology
(Medicine-Section of Pulmonary, Critical Care, and Sleep Medicine)
Pathogenesis of sleep apnea syndrome and regulation of breathing.
Athar Chishti, PhD Professor Pharmacology Organization and regulation of cytoskeleton; role of calpain in platelet and neutrophil activation, and in inflammation.
John Christman, MD Professor and Section Chief Medicine-Section of Pulmonary, Critical Care, and Sleep Medicine
(Pharmacology)
(Center for Lung and Vascular Biology)
Regulation of NF-kappaB activation and role in lung inflammation.
Oscar Colamonici, MD Associate Professor Pharmacology Characterization of structure of interferon receptor and cytokine signaling.
James L. Cook, MD Professor and Section Chief Medicine - Section of Infectious Diseases
(Microbiology and Immunology)
Regulation of apoptosis by adenoviral E1A oncogene; macrophage interaction with anthrax and development of novel therapeutics.
Primal de Lanerolle, PhD Professor Physiology and Biophysics Mechanisms and molecular pharmacology of platelet activation; platelet and endothelial cell interactions.
Xiaoping Du, M.D., PhD Professor Pharmacology Mechanisms and molecular pharmacology of platelet activation; platelet and endothelial cell interactions.
Peter G.W. Gettins, DPhil Professor Biochemistry and Molecular Genetics
(Center for Structural Biology)
Structure and function of serpins such as anti-thrombin and role in thrombosis.
Nissim Hay, PhD Professor Biochemistry and Molecular Genetics Mechanisms of cell survival and cell cycle control; Akt regulation of cell function.
Gail Hecht, MD Professor and Section Chief Medicine-Section of Digestive Disease and Nutrition
(Microbiology and Immunology)
Pathogenesis of E. coli sepsis; E. coli interactions with epithelial cells.
Ronald Hoffman, MD. Professor Medicine-Section of Hematology and Oncology, Cancer Center Biology of stem cells.
Jack Kaplan, PhD Professor and Head Biochemistry and Molecular Genetics Molecular studies of ATPases or ion pumps.
Tohru Kozasa, M.D., PhD Associate Professor Pharmacology Biochemical investigations of
G protein-mediated signal transduction pathways.
Stephen C.-T. Lam, PhD Associate Professor Pharmacology Role of platelet adhesive functions in hemostasis and thrombosis.
Lester F. Lau, Ph.D. Professor Biochemistry and Molecular Genetics Angiogenesis, cell growth, and differentiation.
Guy C. Le Breton, PhD Professor Pharmacology Mechanisms in platelet activation via thromoxane A2 receptors and its inhibition; pharmacological prevention and management of thrombosis.
Theodore Mazzone, MD Professor and Section Chief Medicine- Section of Endocrinology and Metabolism
(Pharmacology)
Biology of macrophages; activation and function of scavenger receptors.
Dolly Mehta, PhD Assistant Professor Pharmacology
(Center for Lung and Vascular Biology)
Role of actin polymerization in activation of endothelial cells and endothelial permeability regulation.
Richard D. Minshall, PhD Associate Professor Anesthesiology
(Pharmacology)
(Center for Lung and Vascular Biology)
Paracellular and transcellular transport; signaling mechanisms regulating permeability of lung endothelium to macromolecules.
Miodrag Radulovacki, MD, PhD Professor Pharmacology
(Medicine-Section of Pulmonary, Critical Care, and Sleep Medicine)
Pathogenic mechanisms of sleep apnea.
Mark M. Rasenick, PhD Professor Physiology and Biophysics Cytoskeletal modulation of G protein signal transduction.
Pradip Raychaudhuri, PhD Professor Biochemistry and Molecular Genetics Regulators of mammalian replication genes.
Randal A. Skidgel, PhD Professor Pharmacology
(Anesthesiology)
(Center for Lung and Vascular Biology)
Analysis of enzymes controlling activity of peptide hormones in lung; regulation of NO production in endothelial cells via carboxypeptidases.
Karen Snapp, PhD Assistant Professor Pharmacology Adhesion and migration mediated by P-selectin and its ligands.
Chinnaswamy Tiruppathi, PhD Associate Professor Pharmacology
(Center for Lung and Vascular Biology)
Synergistic actions of TNFalpha and thrombin in endothelial cell activation; role of Ca2+ signaling in NF-kappaB activation.
Angela Tyner, PhD Professor Biochemistry and Molecular Genetics
(Medicine- Section of Digestive Disease and Nutrition)
Epithelial cell differentiation.
David Ucker, PhD Professor Microbiology and Immunology Control of cellular apoptosis by caspases.
Tatyana Voyno-Yasenetskaya, MD, PhD Associate Professor Pharmacology
(Center for Lung and Vascular Biology)
Study of heterotrimeric G proteins involved in endothelial activation.
Richard Ye, MD, PhD Professor Pharmacology
(Microbiology and Immunology)
(Center for Lung and Vascular Biology)
Chemoattractant activation of phagocytes and generation of directed cell migration and degranulation.

 

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