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Primary Faculty
- Marcelo Bonini, PhD
Assistant Professor
- Graeme Carnegie, PhD
Assistant Professor
- Jaehyung 'Gus' Cho, PhD
Assistant Professor
- Oscar Colamonici, MD
Associate Professor
- Xiaoping Du, MD, PhD
Professor
- Tohru Fukai, MD, PhD
Associate Professor
- Thomas M. Guenthner, PhD
Professor
- Guochang Hu, MD, PhD
Assistant Professor
- Yulia Komarova, PhD
Assistant Professor
- Tohru Kozasa, MD, PhD
Associate Professor
- Stephen C.-T. Lam, PhD
Associate Professor
- Guy C. Le Breton, PhD
Professor
- Asrar B. Malik, PhD
Distinguished Professor and Department Head
- Dolly Mehta, PhD
Associate Professor
- Richard D. Minshall, PhD
Associate Professor
- Shigehiro Nakajima, MD, PhD
Professor
- Viswanathan Natarajan, PhD
Professor
- John P. O'Bryan, PhD
Assistant Professor
- Changwon Park, PhD
Assistant Professor
- Miodrag Radulovacki, MD, PhD
Professor
- Randal A. Skidgel, PhD
Professor
- Chinnaswamy Tiruppathi, PhD
Associate Professor
- Masuko Ushio-Fukai, PhD
Associate Professor
- Kishore K. Wary, PhD
Assistant Professor
- Jingsong Xu, PhD
Assistant Professor
- Richard D. Ye, MD, PhD
Professor
- Jason X.-J.Yuan, PhD
Professor
- You-Yang Zhao, PhD
Assistant Professor
Research Faculty
- Kurt Bachmaier, PhD
- Viktor Brovkovych, PhD
- Anke Di, MD, PhD
- Laila Elsherif, PhD
- Panfeng Fu, PhD
- Xiaopei Gao, MD
- Claudie Hecquet, PhD
- Guochang Hu, MD, PhD
- Rajasingh Johnson, PhD
- Kasim Kabirov, PhD
- Fei Li, PhD
- Xuerong Li, PhD
- Guoquan Liu, PhD
- Yuru Liu, PhD
- Fozia Mir, PhD
- Srikanth Pendyala, MD
- Raudel Sandoval, PhD
- Peter Usatyuk, PhD
- Stephen M. Vogel, PhD
- Zhenjia Wang, PhD
- Kaori Yamada, PhD
- Alexander Zakharov, PhD
- Yidan Zhao, MD, PhD
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Shigehiro Nakajima, MD, PhD
Professor of Pharmacology
Dr. Nakajima's laboratory focuses on the mechanisms involved in the excitation of brain neurons by slow-acting transmitters such as neurotensin and
dopamine. The research addresses the signaling pathways initiated by neurotransmitters that influence ion channel activity, leading to slow excitation of neurons. We are
interested in two types of ion channels which are the principal determinants of excitability, a type of potassium channels (G protein-coupled inward-rectifier K+ channels), and
the other TRPC (transient receptor potential canonical) channels. The investigators work on primary cultured neurons from specific nuclei of the rat brain, such as the nucleus
basalis of Meynert (the main cholinergic neurons of the brain, related to Alzheimer's disease), and the substantia nigra and the ventral tegmental area (dopamine containing
neurons, related to Parkinson's disease and psychiatric disorders). The laboratory uses electro-physiological and the molecular biological approaches to address these questions.
406D CMW
1853 W. Polk St.
(312) 996-0003
Lab home page
Publications
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