News

Recent notable publications from the Department

• Nitric oxide-dependent Src activation and caveolin-1 phosphorylation promotes eNOS/Cav-1 binding and eNOS inhibition. Chen Z, Bakhshi F, Shajahan AN, Mao M, Trane A, Sharma T, Bernatchez P, van NieuwAmerongen GP, Bonini M, Skidgel RA, Malik AB, Minshall RD.  Mol. Biol. Cell 23(7):1388-1398, 2012.


• Cooperative role of caveolin-1 and Cbp in Csk-mediated negative regulation of c-Src. Place AT, Chen Z, Bakhshi F, Liu G, O’Bryan JP, Minshall RD. Mol. Pharmacol 80(4):665-72, 2011.


• Src-dependent phosphorylation of endothelial cell surface ICAM-1 mediates neutrophil adhesion and contributes to the mechanism of lung inflammation. Liu G, Vogel SM, Gao X-P, Javaid K,  Hu G, Danilov SM, Malik AB, Minshall RD. Arterioscler., Thromb., Vasc. Biol. 31(6):1342-50, 2011.


• Sphingosine Kinase 1 Mediation of Expression of the Anaphylatoxin Receptor C5L2 Dampens the Inflammatory Response to Endotoxin. Bachmaier K, Guzman E, Kawamura T, Gao X, Malik AB. PLoS One. 2012;7(2):e30742.


• FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin.
  Mirza MK, Sun Y, Zhao YD, Potula SK, Frey RS, Vogel SM, Malik AB, and Zhao YY. The Journal of Experimental Medicine. 207:1675-1685. 2010.


• NADPH oxidase 2 regulates bone marrow microenvironment following hindlimb ischemia: role in reparative mobilization of progenitor cells. Urao N, McKinney RD, Fukai T, Ushio-Fukai M. Stem Cells. 2012 May;30(5):923-34. doi: 10.1002/stem.1048.


• G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling.
  Gong H, Shen B, Flevaris P, Chow C, Lam SC, Voyno-Yasenetskaya TA, Kozasa T, Du X. Science. 2010 Jan 15;327(5963):340-3.


• Erythrocyte scaffolding protein p55/MPP1 functions as an essential regulator of neutrophil polarity.
  Quinn BJ, Welch EJ, Kim AC, Lokuta MA, Huttenlocher A, Khan AA, Kuchay SM, Chishti AH. Proc Natl Acad Sci(USA). 106: 19842-7, 2009.
  

• Requirement of alpha(4)beta(1) and alpha(5)beta(1) Integrin Expression in Bone-Marrow-Derived Progenitor Cells in Preventing Endotoxin-Induced Lung Vascular Injury and Edema in Mice. Wary KK, Vogel SM, Garrean S, Zhao YD, Malik AB. Stem Cells. 27: 3112-3120. [Epub ahead of print]

• Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration. Zhao YY, Zhao YD, Mirza MK, Huang JH, Potula HH, Vogel SM, Brovkovych V, Yuan JX, Wharton J, Malik AB. J Clin Invest.119: 2009-18, 2009.

• The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin. Knezevic N, Tauseef M, Thennes T, Mehta D. J Exp Med. 206: 2761-77, 2009.

• Filamin A regulates caveolae internalization and trafficking in endothelial cells. Sverdlov M, Shinin V, Place AT, Castellon M, Minshall RD. Mol Biol Cell. 20: 4531-40, 2009.

New Funding/Faculty Awards

• Yuru Liu – R01


• Graeme Carnegie –

CCTS/RRC Supplemental Funding
Faculty Scholarship Support Program-$1K
AHA Scientist Development Grant

• Xiaoping Du – NIH Diversity grant


• Asrar Malik –

  NIH PPG
  Schweppe Investiture (April 2011)
  Microcirculatory Societies Wiederhelm Award
  NIH Diversity supplement
  

• Dolly Mehta – NIH Diversity supplement


• Yulia Komarova – NIH R01


• Viswanathan Natarajan – NIH PPG


• John O’Bryan – CCTS/RRC Supplemental Funding


• Changwon Park – AHA National Scientist Development Grant


• Miodrag Radulovacki – 2010 Co-Inventor of the Year


• Sophie Toya – Parker B. Francis grant 


• Zhenjia Wang –

CCTS/RRC Supplemental Funding
AHA National Scientist Development grant

• Kishore Wary- CCTS/RRC Supplemental Funding   

• Jingsong Xu – NIH Diversity supplement


• Jason Yuan – University Scholar

Department Ranking

The UIC Department of Pharmacology was awarded $10,846,443 in grants and contracts by the NIH for fiscal year 2005. The Department ranks 10^th nationally by dollars awarded medical school pharmacology departments.

Upcoming Conferences

Recent Awards - Congratulations !

STUDENTS AWARDS

• Erin Kohler
  Chancellor's Graduate Research Fellowship Recipient – Fall 2011

• Bo Shen
  Chancellor’s Graduate Research Fellowship  for Spring- Summer 2012

• M Nazir Okur
  Fondation Jerome LeJeune Award (France) – Fall 2011

• Jessica Wilson
  NIH F30 individual predoctoral fellowship

• Xiaowen Liu
  Dean’s Scholar Award, Graduate College Spring 2012

• Chrissie Chow
  Chicago Biomedical Consortium Scholar

• Michael Keegan Delaney
  AHA Predoctoral Fellowship 

• Ram Naikawadi
  AHA Predoctoral Fellowship

• Tracy Thennes
  ASPET Graduate Student Travel Award 2011
  

POSTDOC AWARDS

• Tobias Piegeler
  Eur. Soc. Regional Anesthesia 2011 (Dresden), Best Free Resident PaperMidwest Anesthesia Residents Conference, 2012 (Chicago), 1st Prize, Basic Science


• Uzma Saqib
  Young Scientist Travel Award to the ASPET annual meeting at Experimental Biology 2012 in San Diego, CA – Spring 2012
  

• Nathan Sieracki
  Mirus Research Award in the amount of $2,000. Spring 2012
  
  
• Olga Chernaya
  CCTS/RRC Supplemental Funding

• Mohammad Tauseef
  ASPET Young Scientist Travel Award 2011

Recent Graduates

• Jingyan Han
  Tatyana Voyno-Yasenetskaya, Advisor
  Postdoctoral Fellow, Dept. of Pharmacology, University of Pennsylvania

• Irene Klein
  Asrar Malik, Advisor
  Resident in Internal Medicine at the Mayo School of Graduate Medical Education
  

• Mark Pilkinton
  Oscar Colamonici, Advisor
  Resident in Internal Medicine at Vanderbilt University Med. Center

• Emily Welch
  Richard Ye, Advisor
  Postdoctoral Associate, Dept. of Pharmacology, University of Washington

• Morvarid Mohseni
  Athar H. Chishti, Advisor
  Post-Doctoral Research Fellow, Dept. of Stem Cell and Regenerative Biology at Harvard University

• Hong Yin (Spring 2010)
  Xiaoping Du, Advisor
  Scientist, Stem Cell &Regenerative Medicine International