University of Illinois at Chicago

Head:Jose R. Manaligod, M.D., Ph.D.

Director:R. Prasad, Ph.D.

A.Program of Study

The objectives of the departments graduate program are to develop in the student a confidence in and an enthusiasm for research in pathology and a capacity for independent scientific thought that will enable the graduate to conduct original research in the study of human disease. Since pathology is the scientific study of the alterations produced by disease, the programs general goals include providing students with a solid foundation in the basic pathophysiologic principles underlying disease and in the use of the scientific method to elucidate the causes, pathogenesis, and consequences of disease.

Pathology offers research opportunities to students of diverse scientific interests. The M.S. and Ph.D. degrees are awarded, and a combined professional/graduate degree program is available for medical students. The M.S. degree in pathology is ordinarily completed in two years. Most students are expected to take the Ph.D. track (bypassing the M.S. degree). Such a program usually requires four to five years of study. Students holding professional degrees (M.D., D.D.S., D.V.M.) can generally fulfill the Ph.D. degree requirements in three years. The graduate program in experimental pathology provides an opportunity for the scholar who already has a medical, dental, or veterinary degree to further his or her intellectual skills in the study of disease mechanisms.

Career opportunities differ according to individual training and interests. For example, an M.D., D.D.S., or D.V.M. graduate (or prospective graduate) might want to pursue teaching, a service assignment, or research. For the liberal arts graduate or medical technologist, the goal could be advanced opportunities in laboratory medicine, teaching, research, or any combination of these.



The department provides the following courses for M.S. and Ph.D. degrees. The students also have to take courses from other departments (required and or/elective) to complete the minimum requirements for the degree.

Pathology CoursesCourse Coordinator or Instructor

425General Path, 3hrsH. Polet

426 Organ Path, 5hrsH. Polet

427Clinical Path, 4hrs Bradlow

501Experimental Path, 3hrsR. Prasad

503Molecular Path, 2hrsR. Prasad/M.Mihalov

504Ultrastructural PathR. Buschmann

505Quantitative Morphology, 2hrsR. Buschmann

506Medical Immunology, 2hrsM. Mihalov/R. Prasad

508Pathophysiology I, 3hrsH. Polet

509Pathophysiology II, 3hrsH. Polet

520General Clinical Chemistry, 3hrsR. Williams

522Clinical Biochemistry, 5hrsS. Millner/R. Prasad

527Clinical Laboratory Method Evaluation, 3hrs.R. Williams

534Med. Myco., Parasit. & Vir., 3hrsP. Schreckenberger/W.Janda

595Path Seminar & Journal Club, 2hrsS. Millner/R. Prasad

598Masters Thesis Research, 0-16hrsGraduate Faculty

599Ph.D. Thesis Research, 0-16 hrsGraduate Faculty

530Medical Microbiology, 3 hrsP. Schreckenberger/W. Janda


C.Faculty and Their Research

Shahid M. Ashrafi, PhD, DSc, Associate Professor of Oral Pathology and Histology, Director of Electron Microscopy Facility. Transmission and scanning electron microscopy; cytochemical x-ray micro analysis; calcium transport in relation to mineralization; ultrastructural oral pathology.

Larry D. Brace, Ph.D., Associate Professor of Pathology, Associate Director of Hematology, and Head of the Coagulation Laboratory. Hypercoagulable states; influence of diet and cholesterol-lowering agents on cardiovascular risk factors; anticoagulant, antiplatelet, and antithrombotic agents: thrombosis platelet function.

Basil A. Bradlow, M.D., Professor of Pathology, Director of Clinical Pathology. Thrombosis; atherosclerosis; anticoagulation and lipoproteins; nutrition and cardiovascular disease.

Robert J. Buschmann, Ph.D., Associate Professor of Pathology and Assistant Chief of Operations for Anatomic Pathology, VA Chicago Health Care System-West Side Division.

Phillip J. DeChristopher, M.D., Ph.D., Assistant Professor of Pathology and Director, Blood Bank/Transfusion Medicine. Adverse effects of transfusion; RBC alloimmunization and autoimmunization; stem cell apheresis and transplantation.

Eugene E. Emeson, M.D., Professor of Pathology. Role of cellular immunity in atherosclerosis; transgenic mice as models of human disease.

Egil Fosslien, M.D., Professor of Pathology. Regulation of cell proliferation and apoptosis.

Luna Ghosh, M.D., Professor of Pathology and Chief, Surgical Pathology. Immunochemistry of breast tumors; bone tumors; soft-tissue tumors, diagnostic electron microscopy.

Ronald Hoffman, M.D., Professor of Medicine and Chief of Hematology/Oncology. Hematopoietic stem biology.

William M. Janda, Ph.D., Associate Professor of Pathology and Associate Director of Clinical Microbiology. Pathogenic neisseria; sexually transmitted diseases; retroviral serology; parasitology; anaerobic bacteriology; staphylococci; streptococci.

Wellington Jao, M.D., Professor of Pathology, Chief of Electron Microscopy Laboratory, and Director, Residency Training Program. Ultrastructural pathology and renal diseases and transplantation.

John L. Kennedy, M.D., Clinical Associate Professor of Pathology and Director of Laboratories, Veterans Affairs West Side Medical Center. Bon3-marrow and lymph-node morphology, immunopathology as related to hematology; flow cytometry.

Samuel J. Levin, Ph.D., Assistant Professor of Pathology and Director, Chemical Pathology Laboratory. Clinical chemistry; diagnostic enzymology; toxicology; laboratory test utilization.

Jose R. Manaligod, M.D., Ph.D., Professor of Pathology, Interim Head, and Director, Anatomical Pathology. Renal diseases and transplantation; diagnostic electron microscopy.

Michael L. Mihalov, M.D., Assistant Professor of Pathology., Director of Diagnostic Molecular Pathology. Molecular pathology of lymphoproliferative disorders and viral infection; liver and gastrointestinal pathology.

Seymon N. Millner, Ph.D. , Assistant Professor of Pathology and Section Head, Special Chemistry. Clinical

chemistry; chromatography and electrophoresis: antenatal diagnosis; therapeutic drug monitoring; posttranslational modifications of proteins.

Richard M. Novak, M.D., Associate Professor of Medicine and Director, Infectious Disease Clinic. HIV pathogenesis, antiretroviral agent screening, and development.

Herman Polet, M.D., Professor of Pathology. Consulant, Chemical Pathology laboratory.Growth control of mammalian cells; cellular immunology; cellular pharmacology.

Raymond Pollak, M.D., Professor of Surgery and Chief, Division of Transplantation Surgery. Transplantation immunology research; clinical research in general and organ transplantation surgery.

Rameshwar Prasad, Ph.D., Professor and Director, Pathology Graduate Program. Immunochemistry; structural molecular biology, molecular bisis of human cancer

Salve G. Ronan, M.D., Professor of Pathology and Dermatology. Malignant melanoma and other pigmented lesions.

Paul C. Schreckenberger, Ph.D., Associate Professor of Pathology and Director of Clinical Microbiology Laboratory. Clinical microbiology; pathogenesis of mobiluncus and bacterial vaginosis. Helicobacter pylori disease; nonfermenting bacteria.

Marin Sekosan, M.D., Assistant Professor of Pathology. Lung diseases and transplantation; sleep apnea; lung microvasculature.

Steven D. Sosler, M.S., Assistant Professor of Pathology and Associate Director, Transfusion Medicine Research and Education; SBB (ASCP). Human blood groups; significance of blood group antibodies; immune hemolytic anemias; RBC alloimmunization.

Carol A. Westbrook, M.D., Ph.D., Associate Professor of Medicine and Molecular Genetics. Gene discovery and genomic analysis; tumor suppresor genes in leukemia and breast, colon, and prostate cancer.

Amittha Wickrema, Ph.D., Assistant Professor of Medicine and Pathology and Director, stem Cell/Bone Marrow Processing Laboratory. Gene regulation during hematopoiesis.

Robert H. Williams, Ph.D., Assistant Professor of Pathology and Medical Laboratory Sciences and Section Head, General Chemistry and Toxicology. Clinical chemistry, toxicology, method evaluation, atherosclerosis and renal disease.

D.Correspondence and Information

The University of Illinois at ChicagoDirector of Graduate Studies

1819 W. Polk St.Department of Pathology M/C 847

Chicago, IL 60612-7335Tel: (312)996-2954 Fax: (312)996-7586



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