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Invasive Implants. Destruction and replacement of the preexistent lobular architecture of the adipose tissue by fibroblastic and/ or desmoplastic stroma and chronic inflammation associated with irregular nests of serous epithelium. The epithelial proliferation is seen as irregular glands, papillary formations or single cells (Figures 1-6) which frequently show nuclear features of malignancy (high nuclear/cytoplasmic ratio, nuclear hyperchromatism, and prominent nucleoli) (Figure 7). Submitted by Esther Oliva, MD