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Questions:
1.	Acute oliguria may be seen with all of the following except:
a. lipoid nephrosis (minimal change glomerulonephritis) b. hemolytic transfusion reaction c. crush injury with myoglobinuria d. hemorrhagic shock e. bilateral ureteral calculi

2.	In a consideration of adult polycystic disease of the kidney, all of the following statements are known to be true except:
a. the disease if familial b. the disease is at times unilateral c. the disease is generally asymptomatic until early adult and middle life hematuria, d. hypotension and palpable abdominal masses are frequent clinical findings in symptomatic patients

3.	In consideration of the disease, chronic pyelonephritis, all of the following statements are correct except:
a. This disease must be considered in the differential diagnosis of any patient with nephrotic syndrome. b. There is usually dilatation of the pelvis and calces. c. Patients with this disease may have small contracted kidneys late in the clinical course. d. The gross appearance of the kidneys of patients with this disease are characterized by an uneven scarring.

4.	In the glomberular disease is hematuria most prominent?
a. membranous nephropathy b. acute post-streptococcal glomerulonephritis c. lupus nephritis (membranous type Ñ type V) d. lipoid nephrosis (minimal change glomerulonephritis) e. diabetic glomerulonephropathy

5.	The majority of patients with acute post-streptococcal glomerulonephritis:
a. die from renal failure in a few weeks b. recover completely c. progress through a subacute phase to chronic glomerulonephritis d. pass through a latent period but eventually develop chronic glomerulonephritis e. die from congestive heart failure in a few weeks.

6.	By electronmicroscopy, electron dense deposits can be seen in the glomeruli of patients with the following diseases except
a. BergerÕs disease (IgA nephropathy) b. Post-infectious glomerulonephritis c. Lipoid nephrosis (minimal change disease) d. Membranoproliferative glomerulonephritis, type I e. Diffuse proliferative lupus glomerulonephritis (type IV)

7.	In membranous nephropathy the immune complexes are located:
a. on both sides of the glomerular capillary basement membrane (CBM) b. on the epithelial side of the GBM c. ont the endothelial side of the GBM d. throughout the GBM area e. only in the mesangium

8.	Which of the following is the principal morphologic lesion in analgesic nephropathy?
a. endothelial cell proliferation b. crescent formation c. papillary necrosis d. necrosis of proximal tubular epithelial cells

9.	Pinpoint cortical hemorrhages are a feature of
a. benign nephrosclerosis b. malignant nephrosclerosis c. both d. neither

10.	Onion-skin appearance of the intima of renal arterioles is a feature of :
a. benign nephrosclerosis b. malignant nephrosclerosis c. both d. neither

11.	A 50 year old man has a chief complaint of passing blood in the urine. When questioned further, he states that no pain has been associated with the episodes of bleeding. At this stage, it would be logical to consider in the differential diagnosis all of the following except
a. polyscstic disease of the kidneys b. carcinoma of the kidney c. WilmÕs tumor of the kidney (nephroblastoma) d. Carcinoma of the urinary bladder

12.	Carcinoma of the bladder is most likely to occur in workers exposed to:
a. aniline dyes b. creosote c. nickel d. petroleum waxes e. ultraviolet radiation

13.	The most common tumor of the urinary bladder is:
a. adenocarcinoma b. squamous cell carcinoma c. benign papilloma d. transitional cell carcinoma e. leiomyosarcoma

14.	Which of the following is not a property or a feature of mesangial cells:
a. phagocytosis b. Ia antigen c. Weibel-Palade body d. Actomyosin filaments e. Continuous with tunica media of afferent arteriole


15.	A patient with systemic lupus erythematosus develops an indolent type of nephrotic syndrome. Of the known forms of renal disease in SLE, the most likely type with this clinical setting is:
a. mesangial lupus b. membranous lupus c. tubulo-interstitial nephritis d. focal lupus glomerulonephritis e. diffuse lupus flomerulonephritis

16.	The formation of crescents is one of the ways glomeruli reacts to injury. Crescents are formed by:
a. proliferation of epithelial cells and monocytes b. proliferation of endothelial and mesangial cells c. proliferation of juxtaglomerular cells d. proliferation of parietal epithelial cells only e. herniation of proximal tubular epithelial cells into urinary space

17.	A 12-year old female was admitted for the 8th time because of the nephrotic syndrome. This last hospitalization differed from the others in that steroids were no longer effective in reducing the proteinuria. The likely diagnosis is:
a. chronic glomerulonephritis b. focal segmental glomerulosclerosis c. concersion to membranous glomerulonephritis d. superimposed lupus nephritis e. chronic pyelonephritis

18.	A known heroin addict is admitted for the nephrotic syndrome and the most likely cause is:
a. amyloidosis of the kidney b. BergerÕs disease c. AlportÕs syndrome d. Membranous glomerulonephritis e. Minimal change glomerulonephritis

19.	a. A young patient is noted to have elevated levels of serum alpha feto protein (AFP). After the removal of a unilateral testicular mass, the increased level of AFP decreases and eventually is undetected. The most likely testicular tumor is:
a. seminomal b. mature teratoma c. Sertoli-Leydig cell tumor d. Embryonal cell carcinoma e. Epidermal inclusion cyst of the testes

Please check back periodically, to review updated TLEs. Thanks.

Please direct questions, comments, suggestions to Deb Moulton (dmoult1@uic.edu)