TLE8: Dermatology

Questions: DIRECTIONS: Each of the incomplete statements or questions below is followed by five suggested answers or completions. Select the ONE that is BEST in each case.
1.	One of the following is not a characteristic Tissue Reaction Pattern.
A. Lichenoid B. Psoriasiform C. Spongiosis D. Vesico- bullous E.Panniculitis

2.	One of the following disorders falls into the lichenoid tissue reaction patterns
A. Psoriasis B. Lupus Erythematoshs C. Eczema D. Bullous Remphigoid

3.	The single most critical histologic factor determining the prognosis of malignant melanoma:
A. Number of mitotic figures B. Poor cohesiveness of cells C. Breslow’s depth of invasion D. Clarks levels E. Host Response

4.	All but one of the following histologic criteria are helpful in the pathologic diagnosis of malignant melanoma.
A. Junctional nests of melanocytes B. Single cell melanocytic hyperplasia at the dermal epidermal junction C. A typical melanocyte D. Mitotic figures at the base of lesion E. Asymmetry of proliferating nests of cells in the dermis.

5.	A suprabasalar cell separation is most characteristic of:
A. Bullous pemphigoid B. Dermatitis herpetiforms C. Erythema multiforme D. Pemphigus vulgaris E. Impetigo

6.	The definition of psoriasiform reaction pattern is :
A. Vacuolization of the basal layer B. Subepidermal separation C. Uniform elongation of Rete ridges D. Intraepidermal edema E. Vascular inflammmation

7.	The least important information needed for a proper dermatopathologic diagnosis is :
A. Adequate size of specimen B. Proper processing of specimen C. Family history D. Clinical information of patient E. Expertise of dermatopathologist

8.	The disorder most characteristic of a vasculopathic reation pattern is:
A. Dermatitis herpetiformis B. Intravascular lymphoma C. Psoriasis D. Blastomycosis E. Henoch-Schoulein purpura

9.	A foreign type tissue reaction is characterized histologically by:
A. Diffuse lymphoid infiltrate B. Multinucleated giant cells C. Intraepidermal microabcesses D. Vasculitis E. Spongiosis

10.	Lichen Planus shows all but one of the following histologic changes:
A. Obscuring of dermal-epidermal juntion B. Colloid bodies C. "Saw-toothing" of rete ridges D. Intraepidermal separation E. Lymphoid infilitrate

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Please direct questions, comments, suggestions to Deb Moulton (dmoult1@uic.edu)