Conjunctival Biopsy - Benign Epithelial Neoplasms

The most common benign epithelial neoplasm of the conjunctiva encountered clinically is the squamous papilloma. Be sure to submit these lesions for histologic examination as they may harbor epithelial dysplasia or carcinoma in situ.

Conjunctival papilloma. There was no evidence of disturbed epithelial architecture and no evidence of cytologic atypia. In other words, there was no evidence of dysplasia (conjunctival intraepithelial neoplasia).

It is especially important for the ophthalmologist to prepare the biopsy properly for submission to the laboratory so that the pathologist can render an accurate diagnosis and check margins for involvement in the event of malignancy.